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Related papers: The Learnability Gap in Medical Latent Diffusion

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Generative models based on deep learning have shown significant potential in medical imaging, particularly for modality transformation and multimodal fusion in MRI-based brain imaging. This study introduces GM-LDM, a novel framework that…

Image and Video Processing · Electrical Eng. & Systems 2025-06-17 Hu Xu , Yang Jingling , Jia Sihan , Bi Yuda , Calhoun Vince

Latent diffusion models (LDMs) power state-of-the-art high-resolution generative image models. LDMs learn the data distribution in the latent space of an autoencoder (AE) and produce images by mapping the generated latents into RGB image…

Computer Vision and Pattern Recognition · Computer Science 2025-01-22 Tariq Berrada , Pietro Astolfi , Melissa Hall , Marton Havasi , Yohann Benchetrit , Adriana Romero-Soriano , Karteek Alahari , Michal Drozdzal , Jakob Verbeek

Latent diffusion models (LDMs) dominate high-quality image generation, yet integrating representation learning with generative modeling remains a challenge. We introduce a novel generative image modeling framework that seamlessly bridges…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Theodoros Kouzelis , Efstathios Karypidis , Ioannis Kakogeorgiou , Spyros Gidaris , Nikos Komodakis

Multi-modal data-sets are ubiquitous in modern applications, and multi-modal Variational Autoencoders are a popular family of models that aim to learn a joint representation of the different modalities. However, existing approaches suffer…

Machine Learning · Computer Science 2023-12-19 Mustapha Bounoua , Giulio Franzese , Pietro Michiardi

Neuroimaging data, particularly from techniques like MRI or PET, offer rich but complex information about brain structure and activity. To manage this complexity, latent representation models - such as Autoencoders, Generative Adversarial…

Computer Vision and Pattern Recognition · Computer Science 2024-12-31 C. Vázquez-García , F. J. Martínez-Murcia , F. Segovia Román , Juan M. Górriz

Generative modeling frameworks have emerged as an effective approach to capture high-dimensional image distributions from large datasets without requiring domain-specific knowledge, a capability essential for longitudinal disease…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Ayantika Das , Arunima Sarkar , Keerthi Ram , Mohanasankar Sivaprakasam

Latent diffusion models have emerged as the leading approach for generating high-quality images and videos, utilizing compressed latent representations to reduce the computational burden of the diffusion process. While recent advancements…

Computer Vision and Pattern Recognition · Computer Science 2025-06-10 Ivan Skorokhodov , Sharath Girish , Benran Hu , Willi Menapace , Yanyu Li , Rameen Abdal , Sergey Tulyakov , Aliaksandr Siarohin

Generative learning is a powerful tool for representation learning, and shows particular promise for problems in biomedical imaging. However, in this context, sampling from the distribution is secondary to finding representations of real…

Image and Video Processing · Electrical Eng. & Systems 2022-09-07 Simon Myles Thomas

Medical image segmentation is crucial for clinical diagnosis and treatment planning. Traditional methods typically produce a single segmentation mask, failing to capture inherent uncertainty. Recent generative models enable the creation of…

Computer Vision and Pattern Recognition · Computer Science 2026-02-27 Huynh Trinh Ngoc , Toan Nguyen Hai , Ba Luong Son , Long Tran Quoc

Diffusion models have achieved great success in modeling continuous data modalities such as images, audio, and video, but have seen limited use in discrete domains such as language. Recent attempts to adapt diffusion to language have…

Computation and Language · Computer Science 2023-11-08 Justin Lovelace , Varsha Kishore , Chao Wan , Eliot Shekhtman , Kilian Q. Weinberger

Diffusion models (DMs) have achieved state-of-the-art results for image synthesis tasks as well as density estimation. Applied in the latent space of a powerful pretrained autoencoder (LDM), their immense computational requirements can be…

Computer Vision and Pattern Recognition · Computer Science 2022-10-21 Jeremias Traub

Generative models have achieved remarkable progress with the emergence of flow matching (FM). It has demonstrated strong generative capabilities and attracted significant attention as a simulation-free flow-based framework capable of…

Computer Vision and Pattern Recognition · Computer Science 2026-04-01 Huynh Trinh Ngoc , Hoang Anh Nguyen Kim , Toan Nguyen Hai , Long Tran Quoc

Deep learning has become a popular tool for medical image analysis, but the limited availability of training data remains a major challenge, particularly in the medical field where data acquisition can be costly and subject to privacy…

Image and Video Processing · Electrical Eng. & Systems 2024-06-11 Aghiles Kebaili , Jérôme Lapuyade-Lahorgue , Su Ruan

Despite the surge of deep learning in the past decade, some users are skeptical to deploy these models in practice due to their black-box nature. Specifically, in the medical space where there are severe potential repercussions, we need to…

Computer Vision and Pattern Recognition · Computer Science 2022-04-19 Amil Dravid , Florian Schiffers , Boqing Gong , Aggelos K. Katsaggelos

Deep learning methods have impacted almost every research field, demonstrating notable successes in medical imaging tasks such as denoising and super-resolution. However, the prerequisite for deep learning is data at scale, but data sharing…

Medical Physics · Physics 2024-02-16 Yongyi Shi , Wenjun Xia , Chuang Niu , Christopher Wiedeman , Ge Wang

Diffusion Probabilistic Models (DPMs) suffer from inefficient inference due to their slow sampling and high memory consumption, which limits their applicability to various medical imaging applications. In this work, we propose a novel…

Computer Vision and Pattern Recognition · Computer Science 2025-01-22 Fahim Ahmed Zaman , Mathews Jacob , Amanda Chang , Kan Liu , Milan Sonka , Xiaodong Wu

The lack of large labeled medical imaging datasets, along with significant inter-individual variability compared to clinically established disease classes, poses significant challenges in exploiting medical imaging information in a…

Computer Vision and Pattern Recognition · Computer Science 2022-09-27 Matteo Ferrante , Tommaso Boccato , Simeon Spasov , Andrea Duggento , Nicola Toschi

Large occlusions result in a significant decline in image classification accuracy. During inference, diverse types of unseen occlusions introduce out-of-distribution data to the classification model, leading to accuracy dropping as low as…

Computer Vision and Pattern Recognition · Computer Science 2024-02-13 Ketan Kotwal , Tanay Deshmukh , Preeti Gopal

Modern segmentation models achieve strong predictive performance but remain largely opaque, limiting our ability to diagnose failures, understand dataset shift, or intervene in a principled manner. We introduce Med-SegLens, a model-diffing…

Computer Vision and Pattern Recognition · Computer Science 2026-02-12 Salma J. Ahmed , Emad A. Mohammed , Azam Asilian Bidgoli

In real-world clinical settings, data distributions evolve over time, with a continuous influx of new, limited disease cases. Therefore, class incremental learning is of great significance, i.e., deep learning models are required to learn…

Computer Vision and Pattern Recognition · Computer Science 2024-09-13 Yifei Yao , Hanrong Zhang
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