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This paper proposes a new framework and algorithms to address the problem of diffeomorphic registration on a general class of geometric objects that can be described as discrete distributions of local direction vectors. It builds on both…

Optimization and Control · Mathematics 2018-02-15 Hsi-Wei Hsieh , Nicolas Charon

The individual course of white matter fiber tracts is an important key for analysis of white matter characteristics in healthy and diseased brains. Uniquely, diffusion-weighted MRI tractography in combination with region-based or…

Computer Vision and Pattern Recognition · Computer Science 2018-08-21 Jakob Wasserthal , Peter Neher , Klaus H. Maier-Hein

In shape analysis, finding an optimal 1-1 correspondence between surfaces within a large class of admissible bijective mappings is of great importance. Such process is called surface registration. The difficulty lies in the fact that the…

Optimization and Control · Mathematics 2010-05-19 L. M. Lui , T. W. Wong , W. Zeng , X. F. Gu , P. M. Thompson , T. F. Chan , S. T. Yau

The brain white matter consists of a set of tracts that connect distinct regions of the brain. Segmentation of these tracts is often needed for clinical and research studies. Diffusion-weighted MRI offers unique contrast to delineate these…

Image and Video Processing · Electrical Eng. & Systems 2023-07-06 Hamza Kebiri , Ali Gholipour , Meritxell Bach Cuadra , Davood Karimi

Predicting interactions between biomolecules, such as protein-protein complexes, remains a challenging problem. Despite the many advancements done so far, the performances of docking protocols are deeply dependent on their capability of…

Biomolecules · Quantitative Biology 2025-08-19 Greta Grassmann , Lorenzo Di Rienzo , Giancarlo Ruocco , Mattia Miotto , Edoardo Milanetti

We present cortical surface parcellation using spherical deep convolutional neural networks. Traditional multi-atlas cortical surface parcellation requires inter-subject surface registration using geometric features with high processing…

White matter tract microstructure has been shown to influence neuropsychological scores of cognitive performance. However, prediction of these scores from white matter tract data has not been attempted. In this paper, we propose a…

Computer Vision and Pattern Recognition · Computer Science 2022-07-07 Yuqian Chen , Fan Zhang , Chaoyi Zhang , Tengfei Xue , Leo R. Zekelman , Jianzhong He , Yang Song , Nikos Makris , Yogesh Rathi , Alexandra J. Golby , Weidong Cai , Lauren J. O'Donnell

Surface-based cortical analysis is valuable for a variety of neuroimaging tasks, such as spatial normalization, parcellation, and gray matter (GM) thickness estimation. However, most tools for estimating cortical surfaces work exclusively…

Accurate cortical surface reconstruction from magnetic resonance imaging (MRI) data is crucial for reliable neuroanatomical analyses. Current methods have to contend with complex cortical geometries, strict topological requirements, and…

Image and Video Processing · Electrical Eng. & Systems 2025-10-22 Kaveh Moradkhani , R Jarrett Rushmore , Sylvain Bouix

The proliferation and ubiquity of temporal data across many disciplines has sparked interest for similarity, classification and clustering methods specifically designed to handle time series data. A core issue when dealing with time series…

Machine Learning · Computer Science 2023-09-26 Iñigo Martinez

Many algorithms for surface registration risk producing significant errors if surfaces are significantly nonisometric. Manifold learning has been shown to be effective at improving registration quality, using information from an entire…

Graphics · Computer Science 2021-01-13 Robert J. Ravier

Accurately registering breast MR images from different time points enables the alignment of anatomical structures and tracking of tumor progression, supporting more effective breast cancer detection, diagnosis, and treatment planning.…

Image and Video Processing · Electrical Eng. & Systems 2026-01-01 Yaqian Chen , Hanxue Gu , Haoyu Dong , Qihang Li , Yuwen Chen , Nicholas Konz , Lin Li , Maciej A. Mazurowski

Streamline classification is essential to identify anatomically meaningful white matter tracts from diffusion MRI (dMRI) tractography. However, current streamline classification methods rely primarily on the geometric features of the…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Haotian Yan , Bocheng Guo , Jianzhong He , Nir A. Sochen , Ofer Pasternak , Lauren J O'Donnell , Fan Zhang

The human visual system exhibits non-uniform spatial resolution across the visual field, which is characterized by the cortical magnification factor (CMF) that reflects its anatomical basis. However, current approaches for quantifying CMF…

Neurons and Cognition · Quantitative Biology 2025-12-09 Yujian Xiong , Negar Jalili Mallak , Yanshuai Tu , Zhong-Lin Lu , Yalin Wang

The majority of current research in deep learning based image registration addresses inter-patient brain registration with moderate deformation magnitudes. The recent Learn2Reg medical registration benchmark has demonstrated that…

Computer Vision and Pattern Recognition · Computer Science 2022-03-02 Mattias P. Heinrich , Lasse Hansen

Currently, cortical surface registration techniques based on classical methods have been well developed. However, a key issue with classical methods is that for each pair of images to be registered, it is necessary to search for the optimal…

Computer Vision and Pattern Recognition · Computer Science 2024-10-22 Ruoyu Zhang , Lihui Wang , Kun Tang , Jingwen Xu , Hongjiang Wei

Cortical thickness measurements from magnetic resonance imaging, an important biomarker in many neurodegenerative and neurological disorders, are derived by many tools from an initial voxel-wise tissue segmentation. White matter (WM)…

Image and Video Processing · Electrical Eng. & Systems 2025-03-27 Vinzenz Uhr , Ivan Diaz , Christian Rummel , Richard McKinley

Registration, which aims to find an optimal one-to-one correspondence between different data, is an important problem in various fields. This problem is especially challenging when large deformations occur. In this paper, we present a novel…

Differential Geometry · Mathematics 2013-10-08 Lam Ka Chun , Lok Ming Lui

Diffusion magnetic resonance imaging (dMRI) and tractography provide means to study the anatomical structures within the white matter of the brain. When studying tractography data across subjects, it is usually necessary to align, i.e. to…

Machine Learning · Statistics 2016-02-01 Thien Bao Nguyen , Emanuele Olivetti , Paolo Avesani

Cortical surface registration plays a crucial role in aligning cortical functional and anatomical features across individuals. However, conventional registration algorithms are computationally inefficient. Recently, learning-based…

Image and Video Processing · Electrical Eng. & Systems 2023-07-04 Jianxun Ren , Ning An , Youjia Zhang , Danyang Wang , Zhenyu Sun , Cong Lin , Weigang Cui , Weiwei Wang , Ying Zhou , Wei Zhang , Qingyu Hu , Ping Zhang , Dan Hu , Danhong Wang , Hesheng Liu