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Implementing an autonomous vehicle that is able to output feasible, smooth and efficient trajectories is a long-standing challenge. Several approaches have been considered, roughly falling under two categories: rule-based and learning-based…

Robotics · Computer Science 2022-03-22 Branka Mirchevska , Moritz Werling , Joschka Boedecker

Learning effective reinforcement learning (RL) policies to solve real-world complex tasks can be quite challenging without a high-fidelity simulation environment. In most cases, we are only given imperfect simulators with simplified…

Machine Learning · Computer Science 2025-10-16 Haoyi Niu , Shubham Sharma , Yiwen Qiu , Ming Li , Guyue Zhou , Jianming Hu , Xianyuan Zhan

Simultaneously optimizing multiple, frequently conflicting, molecular properties is a key bottleneck in the development of novel therapeutics. Although a promising approach, the efficacy of multi-task learning is often compromised by…

Machine Learning · Computer Science 2025-10-01 Mason Minot , Gisbert Schneider

Reinforcement Learning (RL) has proven largely effective in obtaining stable locomotion gaits for legged robots. However, designing control algorithms which can robustly navigate unseen environments with obstacles remains an ongoing problem…

Robotics · Computer Science 2025-03-17 Jose-Luis Holgado-Alvarez , Aryaman Reddi , Carlo D'Eramo

Object goal navigation is an important problem in Embodied AI that involves guiding the agent to navigate to an instance of the object category in an unknown environment -- typically an indoor scene. Unfortunately, current state-of-the-art…

Computer Vision and Pattern Recognition · Computer Science 2023-05-29 Junting Chen , Guohao Li , Suryansh Kumar , Bernard Ghanem , Fisher Yu

Synthesizable molecular design (also known as synthesizable molecular optimization) is a fundamental problem in drug discovery, and involves designing novel molecular structures to improve their properties according to drug-relevant oracle…

Machine Learning · Computer Science 2026-05-07 Dannong Wang , Jintai Chen , Yingzhou Lu , Minjie Shen , Lulu Chen , Zhiding Liang , Tianfan Fu , Xiao-Yang Liu

Accurate prediction of energy and forces for 3D molecular systems is one of fundamental challenges at the core of AI for Science applications. Many powerful and data-efficient neural networks predict molecular energies and forces from…

Chemical Physics · Physics 2026-04-23 Ali Mollahosseini , Mohammed Haroon Dupty , Wee Sun Lee

This study presents a benchmark for evaluating action-constrained reinforcement learning (RL) algorithms. In action-constrained RL, each action taken by the learning system must comply with certain constraints. These constraints are crucial…

Machine Learning · Computer Science 2023-06-30 Kazumi Kasaura , Shuwa Miura , Tadashi Kozuno , Ryo Yonetani , Kenta Hoshino , Yohei Hosoe

Safe and effective motion planning is crucial for autonomous robots. Diffusion models excel at capturing complex agent interactions, a fundamental aspect of decision-making in dynamic environments. Recent studies have successfully applied…

Robotics · Computer Science 2025-07-18 Giwon Lee , Daehee Park , Jaewoo Jeong , Kuk-Jin Yoon

Reinforcement learning (RL) and Deep Reinforcement Learning (DRL), in particular, have the potential to disrupt and are already changing the way we interact with the world. One of the key indicators of their applicability is their ability…

Machine Learning · Computer Science 2024-08-20 Nikolai Rozanov

Deep Reinforcement Learning (DRL) has become a powerful methodology to solve complex decision-making problems. However, DRL has several limitations when used in real-world problems (e.g., robotics applications). For instance, long training…

Robotics · Computer Science 2019-08-15 Rodrigo Pérez-Dattari , Carlos Celemin , Javier Ruiz-del-Solar , Jens Kober

Two less addressed issues of deep reinforcement learning are (1) lack of generalization capability to new target goals, and (2) data inefficiency i.e., the model requires several (and often costly) episodes of trial and error to converge,…

Computer Vision and Pattern Recognition · Computer Science 2016-09-19 Yuke Zhu , Roozbeh Mottaghi , Eric Kolve , Joseph J. Lim , Abhinav Gupta , Li Fei-Fei , Ali Farhadi

Mobile manipulation tasks remain one of the critical challenges for the widespread adoption of autonomous robots in both service and industrial scenarios. While planning approaches are good at generating feasible whole-body robot…

Robotics · Computer Science 2021-11-05 Daniel Honerkamp , Tim Welschehold , Abhinav Valada

A central challenge in quantum information science and technology is achieving real-time estimation and feedforward control of quantum systems. This challenge is compounded by the inherent inhomogeneity of quantum resources, such as qubit…

Machine Learning · Computer Science 2024-05-28 Linsen Li , Pratyush Anand , Kaiming He , Dirk Englund

Defects in extrusion additive manufacturing remain common despite its prevalent use. While numerous AI-driven approaches have been proposed to improve quality assurance, the inherently dynamic nature of the printing process poses persistent…

Systems and Control · Electrical Eng. & Systems 2026-01-21 Xiaohan Li , Sebastian Pattinson

The fundamental goal of generative drug design is to propose optimized molecules that meet predefined activity, selectivity, and pharmacokinetic criteria. Despite recent progress, we argue that existing generative methods are limited in…

Chemical Physics · Physics 2020-12-17 Julien Horwood , Emmanuel Noutahi

Goal-directed Reinforcement Learning (RL) traditionally considers an agent interacting with an environment, prescribing a real-valued reward to an agent proportional to the completion of some goal. Goal-directed RL has seen large gains in…

Machine Learning · Computer Science 2020-10-28 Sharath Chandra Raparthy , Bhairav Mehta , Florian Golemo , Liam Paull

A reinforcement learning (RL) framework is introduced for the efficient synthesis of quantum circuits that generate specified target quantum states from a fixed initial state, addressing a central challenge in both the Noisy…

Quantum Physics · Physics 2026-02-18 Sara Giordano , Kornikar Sen , Miguel A. Martin-Delgado

We develop an optimization framework centered around a core idea: once a (parametric) policy is specified, control authority is transferred to the policy, resulting in an autonomous dynamical system. Thus we should be able to optimize…

Machine Learning · Computer Science 2025-06-11 Emo Todorov

One of the bottlenecks preventing Deep Reinforcement Learning algorithms (DRL) from real-world applications is how to explore the environment and collect informative transitions efficiently. The present paper describes bounded exploration,…

Machine Learning · Computer Science 2024-12-10 Ting Qiao , Henry Williams , David Valencia , Bruce MacDonald
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