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We propose ProtoArgNet, a novel interpretable deep neural architecture for image classification in the spirit of prototypical-part-learning as found, e.g., in ProtoPNet. While earlier approaches associate every class with multiple…

Computer Vision and Pattern Recognition · Computer Science 2025-04-16 Hamed Ayoobi , Nico Potyka , Francesca Toni

Large language models (LLMs) are increasingly recognized as valuable tools across the medical environment, supporting clinical, research, and administrative workflows. However, strict privacy and network security regulations in hospital…

Computation and Language · Computer Science 2026-01-09 Seokhwan Ko , Donghyeon Lee , Jaewoo Chun , Hyungsoo Han , Junghwan Cho

The BioModels database is one of the premier databases for computational models in systems biology. The database contains over 1000 curated models and an even larger number of non-curated models. All the models are stored in the…

Molecular Networks · Quantitative Biology 2026-02-02 Bhavyahshree Navaneetha Krishnan , Adel Heydarabadipour , Herbert Sauro

Retrieval-Augmented Generation (RAG) utilizes external knowledge to augment Large Language Models' (LLMs) reliability. For flexibility, agentic RAG employs autonomous, multi-round retrieval and reasoning to resolve queries. Although recent…

Information Retrieval · Computer Science 2025-11-10 Chao Zhang , Yuhao Wang , Derong Xu , Haoxin Zhang , Yuanjie Lyu , Yuhao Chen , Shuochen Liu , Tong Xu , Xiangyu Zhao , Yan Gao , Yao Hu , Enhong Chen

We propose a novel inherently interpretable machine learning method that bases decisions on few relevant examples that we call prototypes. Our method, ProtoAttend, can be integrated into a wide range of neural network architectures…

Machine Learning · Computer Science 2019-09-27 Sercan O. Arik , Tomas Pfister

Survival analysis is critical for cancer prognosis and treatment planning, yet existing methods lack the transparency essential for clinical adoption. While recent pathology agents have demonstrated explainability in diagnostic tasks, they…

Computer Vision and Pattern Recognition · Computer Science 2025-11-21 Guolin Huang , Wenting Chen , Jiaqi Yang , Xinheng Lyu , Xiaoling Luo , Sen Yang , Xiaohan Xing , Linlin Shen

The integration of deep learning-based glaucoma detection with large language models (LLMs) presents an automated strategy to mitigate ophthalmologist shortages and improve clinical reporting efficiency. However, applying general LLMs to…

Multiagent Systems · Computer Science 2025-12-18 Philip R. Liu , Sparsh Bansal , Jimmy Dinh , Aditya Pawar , Ramani Satishkumar , Shail Desai , Neeraj Gupta , Xin Wang , Shu Hu

Medical Large Vision-Language Models (Med-LVLMs) have been widely adopted for medical report generation. Despite Med-LVLMs producing state-of-the-art performance, they exhibit a bias toward predicting all findings as normal, leading to…

Multiagent Systems · Computer Science 2025-05-27 Pengyu Wang , Shuchang Ye , Usman Naseem , Jinman Kim

Emergency departments worldwide face rising patient volumes, workforce shortages, and variability in triage decisions that threaten the delivery of timely and accurate care. Current triage methods rely primarily on vital signs, routine…

Quantitative Methods · Quantitative Biology 2025-10-21 Kerem Delikoyun , Qianyu Chen , Win Sen Kuan , John Tshon Yit Soong , Matthew Edward Cove , Oliver Hayden

Large language model (LLM) agents extend generative models with reasoning, tool use, and persistent memory, thereby enabling the automation of complex tasks. In healthcare, such systems could support documentation, care coordination, and…

Artificial Intelligence · Computer Science 2026-03-24 Wenxian Yang , Hanzheng Qiu , Bangqun Zhang , Chengquan Li , Zhiyong Huang , Xiaobin Feng , Rongshan Yu , Jiahong Dong

Large Language Models (LLMs) achieve competitive results compared to human experts in medical examinations. However, it remains a challenge to apply LLMs to complex clinical decision-making, which requires a deep understanding of medical…

LLM-based agents have emerged as transformative tools capable of executing complex tasks through iterative planning and action, achieving significant advancements in understanding and addressing user needs. Yet, their effectiveness remains…

Human-Computer Interaction · Computer Science 2025-08-26 Mithat Can Ozgun , Jiahuan Pei , Koen Hindriks , Lucia Donatelli , Qingzhi Liu , Junxiao Wang

Background: Patient-facing medical chatbots based on retrieval-augmented generation (RAG) are increasingly promoted to deliver accessible, grounded health information. AI-assisted development lowers the barrier to building them, but they…

Cryptography and Security · Computer Science 2026-05-04 Alfredo Madrid-García , Miguel Rujas

Large Language Models (LLMs) have been widely adopted in conversational applications. However, their reliance on parametric knowledge limits reliability in real-world scenarios that require dynamic or domain-specific information.…

Computation and Language · Computer Science 2026-05-26 Kaiqiao Han , LuAn Tang , Renliang Sun , Peng Yuan , Wei Cheng , Haoyu Wang , Wei Wang , Yizhou Sun , Haifeng Chen

Interactive medical questioning is essential in real-world clinical consultations, where physicians must actively gather information from patients. While medical Large Language Models (LLMs) have shown impressive capabilities in static…

Computation and Language · Computer Science 2025-08-20 Hongxin Ding , Baixiang Huang , Yue Fang , Weibin Liao , Xinke Jiang , Zheng Li , Junfeng Zhao , Yasha Wang

Multimodal artificial intelligence (AI) systems have the potential to enhance clinical decision-making by interpreting various types of medical data. However, the effectiveness of these models across all medical fields is uncertain. Each…

In meta-learning approaches, it is difficult for a practitioner to make sense of what kind of representations the model employs. Without this ability, it can be difficult to both understand what the model knows as well as to make meaningful…

Machine Learning · Computer Science 2022-04-05 Pedro Sandoval-Segura , Wallace Lawson

The adoption of Deep Learning algorithms in the medical imaging field is a prominent area of research, with high potential for advancing AI-based Computer-aided diagnosis (AI-CAD) solutions. However, current solutions face challenges due to…

Computer Vision and Pattern Recognition · Computer Science 2024-12-30 Iury B. de A. Santos , André C. P. L. F. de Carvalho

We introduce a novel graph-based Retrieval-Augmented Generation (RAG) framework specifically designed for the medical domain, called \textbf{MedGraphRAG}, aimed at enhancing Large Language Model (LLM) capabilities for generating…

Computer Vision and Pattern Recognition · Computer Science 2024-10-17 Junde Wu , Jiayuan Zhu , Yunli Qi , Jingkun Chen , Min Xu , Filippo Menolascina , Vicente Grau

Memory-Augmented Generation (MAG) extends Large Language Models with external memory to support long-context reasoning, but existing approaches largely rely on semantic similarity over monolithic memory stores, entangling temporal, causal,…

Artificial Intelligence · Computer Science 2026-04-17 Dongming Jiang , Yi Li , Guanpeng Li , Bingzhe Li
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