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Clinical trials are critical for advancing medical treatments but remain prohibitively expensive and time-consuming. Accurate prediction of clinical trial outcomes can significantly reduce research and development costs and accelerate drug…
Large language models (LLMs) remain unreliable for high-stakes claim verification due to hallucinations and shallow reasoning. While retrieval-augmented generation (RAG) and multi-agent debate (MAD) address this, they are limited by…
Large Language Model (LLM)-based recommendation systems have demonstrated remarkable capabilities in understanding user preferences and generating personalized suggestions. However, existing approaches face critical challenges in…
Evaluating large language models (LLMs) has recently emerged as a critical issue for safe and trustworthy application of LLMs in the medical domain. Although a variety of static medical question-answering (QA) benchmarks have been proposed,…
The adoption of large language models (LLMs) in healthcare has attracted significant research interest. However, their performance in healthcare remains under-investigated and potentially limited, due to i) they lack rich domain-specific…
Retrieval-augmented generation (RAG) has emerged as a promising approach to enhance the performance of large language models (LLMs) in knowledge-intensive tasks such as those from medical domain. However, the sensitive nature of the medical…
While state-of-the-art language models (LMs) surpass the vast majority of humans in certain domains, their reasoning remains largely opaque, undermining trust in their output. Furthermore, while autoregressive LMs can output explicit…
The vast amount of biomedical information available today presents a significant challenge for investigators seeking to digest, process, and understand these findings effectively. Large Language Models (LLMs) have emerged as powerful tools…
Misdiagnosis causes significant harm to healthcare systems worldwide, leading to increased costs and patient risks. MedRAG is a smart multimodal healthcare copilot equipped with powerful large language model (LLM) reasoning, designed to…
Recent advances in autonomous digital agents from industry (e.g., Manus AI and Gemini's research mode) highlight potential for structured tasks by autonomous decision-making and task decomposition; however, it remains unclear to what extent…
The rapid spread of memes makes harmful content detection increasingly crucial, as effective identification can curb the circulation of misinformation. However, existing methods rely heavily on high-volume annotated data, which leads to…
Large Language Models (LLMs) exhibit high reasoning capacity in medical question-answering, but their tendency to produce hallucinations and outdated knowledge poses critical risks in healthcare fields. While Retrieval-Augmented Generation…
Advanced Persistent Threats (APTs) pose critical challenges to modern cybersecurity due to their multi-stage and stealthy nature. While provenance-based detection approaches show promise in capturing causal attack semantics, current threat…
Large language models (LLMs) offer new opportunities for constructing knowledge graphs (KGs) from unstructured clinical narratives. However, existing approaches often rely on structured inputs and lack robust validation of factual accuracy…
Large language models (LLMs) have shown promise in medical question answering but often struggle with hallucinations and shallow reasoning, particularly in tasks requiring nuanced clinical understanding. Retrieval-augmented generation (RAG)…
Multimodal Retrieval-Augmented Generation (MRAG) enhances large language models (LLMs) by integrating multimodal data (text, images, videos) into retrieval and generation processes, overcoming the limitations of text-only…
Multimodal Retrieval-Augmented Generation (MRAG) systems enhance LMMs by integrating external multimodal databases, but introduce unexplored privacy vulnerabilities. While text-based RAG privacy risks have been studied, multimodal data…
Retrieval-Augmented Generation (RAG) enables large language models (LLMs) to access external knowledge sources, but the effectiveness of RAG relies on the coordination between the retriever and the generator. Since these components are…
Large-scale single-cell and Perturb-seq investigations routinely involve clustering cells and subsequently annotating each cluster with Gene-Ontology (GO) terms to elucidate the underlying biological programs. However, both stages,…
Autonomous agents utilizing Large Language Models (LLMs) have demonstrated remarkable capabilities in isolated medical tasks like diagnosis and image analysis, but struggle with integrated clinical workflows that connect diagnostic…