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Large language models (LLMs) trained with next-word-prediction have achieved success as clinical foundation models. Representations from these language backbones yield strong linear probe performance across biomedical tasks, suggesting that…

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Ophthalmologists typically require multimodal data sources to improve diagnostic accuracy in clinical decisions. However, due to medical device shortages, low-quality data and data privacy concerns, missing data modalities are common in…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Chengzhi Liu , Zile Huang , Zhe Chen , Feilong Tang , Yu Tian , Zhongxing Xu , Zihong Luo , Yalin Zheng , Yanda Meng

The availability of large and deep electronic healthcare records (EHR) datasets has the potential to enable a better understanding of real-world patient journeys, and to identify novel subgroups of patients. ML-based aggregation of EHR data…

Machine Learning · Computer Science 2022-08-03 Owen Parsons , Nathan E Barlow , Janie Baxter , Karen Paraschin , Andrea Derix , Peter Hein , Robert Dürichen

While recent multimodal large language models (MLLMs) have advanced automated ECG interpretation, they still face two key limitations: (1) insufficient multimodal synergy between time series signals and visual ECG representations, and (2)…

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The abundance of intestinal flora is closely related to human diseases, but diseases are not caused by a single gut microbe. Instead, they result from the complex interplay of numerous microbial entities. This intricate and implicit…

Artificial Intelligence · Computer Science 2024-08-01 Dingkun Liu , Hongjie Zhou , Yilu Qu , Huimei Zhang , Yongdong Xu

Mental disorders present challenges in diagnosis and treatment due to their complex and heterogeneous nature. Electroencephalogram (EEG) has shown promise as a potential biomarker for these disorders. However, existing methods for analyzing…

Methodology · Statistics 2024-01-30 Xingche Guo , Bin Yang , Ji Meng Loh , Qinxia Wang , Yuanjia Wang

Foundation large language models (LLMs) have shown an impressive ability to solve tasks across a wide range of fields including health. To effectively solve personalized health tasks, LLMs need the ability to ingest a diversity of data…

Multi-institutional electronic health record (Multi-EHR) data have emerged as a powerful resource for developing predictive models to support clinical decisions and for generating reliable real-world evidence. By aggregating information…

Methodology · Statistics 2026-05-12 Yuming Zhang , Congyuan Duan , Dong Xia , Doudou Zhou , Tianxi Cai

Radiology report generation (RRG) models typically focus on individual exams, often overlooking the integration of historical visual or textual data, which is crucial for patient follow-ups. Traditional methods usually struggle with long…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Tengfei Liu , Jiapu Wang , Yongli Hu , Mingjie Li , Junfei Yi , Xiaojun Chang , Junbin Gao , Baocai Yin

Multi-view graph embedding has become a widely studied problem in the area of graph learning. Most of the existing works on multi-view graph embedding aim to find a shared common node embedding across all the views of the graph by combining…

Machine Learning · Computer Science 2017-09-13 Guixiang Ma , Chun-Ta Lu , Lifang He , Philip S. Yu , Ann B. Ragin

Electronic health records (EHR) contain narrative notes that provide extensive details on the medical condition and management of patients. Natural language processing (NLP) of clinical notes can use observed frequencies of clinical terms…

Computation and Language · Computer Science 2023-07-04 Bryan Cai , Sihang Zeng , Yucong Lin , Zheng Yuan , Doudou Zhou , Lu Tian

Medical deep learning models depend heavily on domain-specific knowledge to perform well on knowledge-intensive clinical tasks. Prior work has primarily leveraged unimodal knowledge graphs, such as the Unified Medical Language System…

Artificial Intelligence · Computer Science 2025-05-26 Xiaochen Wang , Yuan Zhong , Lingwei Zhang , Lisong Dai , Ting Wang , Fenglong Ma

Multimodal recommendation combines the user historical behaviors with the modal features of items to capture the tangible user preferences, presenting superior performance compared to the conventional ID-based recommender systems. However,…

Information Retrieval · Computer Science 2026-01-27 Yuzhuo Dang , Xin Zhang , Zhiqiang Pan , Yuxiao Duan , Wanyu Chen , Fei Cai , Honghui Chen

Clinical outcome prediction plays an important role in stroke patient management. From a machine learning point-of-view, one of the main challenges is dealing with heterogeneous data at patient admission, i.e. the image data which are…

Image and Video Processing · Electrical Eng. & Systems 2022-05-12 Nima Hatami , Tae-Hee Cho , Laura Mechtouff , Omer Faruk Eker , David Rousseau , Carole Frindel

The integration of diverse clinical modalities such as medical imaging and the tabular data extracted from patients' Electronic Health Records (EHRs) is a crucial aspect of modern healthcare. Integrative analysis of multiple sources can…

Computer Vision and Pattern Recognition · Computer Science 2025-04-22 Daniel Duenias , Brennan Nichyporuk , Tal Arbel , Tammy Riklin Raviv

Measures to predict 30-day readmission are considered an important quality factor for hospitals as accurate predictions can reduce the overall cost of care by identifying high risk patients before they are discharged. While recent deep…

Machine Learning · Computer Science 2023-04-06 Siyi Tang , Amara Tariq , Jared Dunnmon , Umesh Sharma , Praneetha Elugunti , Daniel Rubin , Bhavik N. Patel , Imon Banerjee

Human motion plays an important role in many fields. Large databases exist that store and make available recordings of human motions. However, annotating each motion with multiple labels is a cumbersome and error-prone process. This…

Machine Learning · Computer Science 2016-05-06 Matthias Plappert

Modeling temporal multimodal data poses significant challenges in classification tasks, particularly in capturing long-range temporal dependencies and intricate cross-modal interactions. Audiovisual data, as a representative example, is…

Machine Learning · Computer Science 2025-08-05 Feng Xu , Hui Wang , Yuting Huang , Danwei Zhang , Zizhu Fan

Results from multiple diagnostic tests are usually combined to improve the overall diagnostic accuracy. For binary classification, maximization of the empirical estimate of the area under the receiver operating characteristic (ROC) curve is…

Methodology · Statistics 2026-04-16 Raju Maiti , Jialiang Li , Priyam Das , Lei Feng , Derek Hausenloy , Bibhas Chakraborty

Computational pathology models that use digitized histopathology whole-slide images have the potential to become a cost-effective and scalable alternative to molecular assays for the prediction of genomic biomarkers, a key task in precision…

Quantitative Methods · Quantitative Biology 2026-03-03 Ekaterina Redekop , Eric Zimmermann , Ava P Amini , Alex X Lu , Neil Tenenholtz , James Brian Hall , Lorin Crawford , Kristen A Severson