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Auscultation, particularly heart sound, is a non-invasive technique that provides essential vital sign information. Recently, self-supervised acoustic representation foundation models (FMs) have been proposed to offer insights into…

Cardiac arrhythmogenesis is governed by complex electromechanical interactions that are not directly observable in vivo, motivating the development of non-invasive computational approaches for reconstructing three-dimensional activation…

Medical Physics · Physics 2026-03-05 Nathan Dermul , Hans Dierckx

An important paradigm in smart health is developing diagnosis tools and monitoring a patient's heart activity through processing Electrocardiogram (ECG) signals is a key example, sue to high mortality rate of heart-related disease. However,…

Signal Processing · Electrical Eng. & Systems 2018-11-02 Jiaming Chen , Ali Valehi , Abolfazl Razi

Recently, deep generative models have been used for posterior inference in inverse problems, including high-stakes applications in medical imaging and scientific discovery, where the uncertainty of a prediction can matter as much as the…

Machine Learning · Computer Science 2026-05-15 Yuxin Guo , Dongrui Deng , Pulkit Grover

Cardiovascular disease has become one of the most significant threats endangering human life and health. Recently, Electrocardiogram (ECG) monitoring has been transformed into remote cardiac monitoring by Holter surveillance. However, the…

Signal Processing · Electrical Eng. & Systems 2022-01-26 Peng Wang , Zihuai Lin , Xucun Yan , Zijiao Chen , Ming Ding , Yang Song , Lu Meng

Advances in computational science offer a principled pipeline for predictive modeling of cardiovascular flows and aspire to provide a valuable tool for monitoring, diagnostics and surgical planning. Such models can be nowadays deployed on…

Machine Learning · Computer Science 2019-09-19 Georgios Kissas , Yibo Yang , Eileen Hwuang , Walter R. Witschey , John A. Detre , Paris Perdikaris

Despite of the pain and limited accuracy of blood tests for early recognition of cardiovascular disease, they dominate risk screening and triage. On the other hand, heart rate variability is non-invasive and cheap, but not considered…

Neural and Evolutionary Computing · Computer Science 2016-12-30 Tamas Madl

Deep learning-based cardiac segmentation has seen significant advancements over the years. Many studies have tackled the challenge of anatomically incorrect segmentation predictions by introducing auxiliary modules. These modules either…

Computer Vision and Pattern Recognition · Computer Science 2025-02-24 Zahid Ullah , Jihie Kim

Accurate simulation of brain deformation is a key component for developing realistic, interactive neurosurgical simulators, as complex nonlinear deformations must be captured to ensure realistic tool-tissue interactions. However,…

The inverse mechano-electrical problem in cardiac electrophysiology is the attempt to reconstruct electrical excitation or action potential wave patterns from the heart's mechanical deformation that occurs in response to electrical…

Image and Video Processing · Electrical Eng. & Systems 2021-11-10 Jan Christoph , Jan Lebert

Our evolving understanding of the heterocellular cardiac environment demands innovative tools for its study. While murine models are lauded for their versatility and accessibility, they are constrained by scale; tools designed for larger…

Biological Physics · Physics 2023-12-12 Gavin Tumlinson , Enaam Chleilat , Josef Madl , Peter Kohl , Viviane Timmermann

Mapping resolution has recently been identified as a key limitation in successfully locating the drivers of atrial fibrillation. Using a simple cellular automata model of atrial fibrillation, we demonstrate a method by which re-entrant…

Tissues and Organs · Quantitative Biology 2020-01-27 Max Falkenberg McGillivray , William Cheng , Nicholas S. Peters , Kim Christensen

Electrocardiogram (ECG) signals are often degraded by various noise sources such as baseline wander, motion artifacts, and electromyographic interference, posing a major challenge in clinical settings. This paper presents a lightweight deep…

Signal Processing · Electrical Eng. & Systems 2025-11-18 Mahdi Pirayesh Shirazi Nejad , David Hicks , Matt Valentine , Ki H. Chon

Solving inverse problems in cardiac electrophysiology consists in the recovery of physiological parameters from surface electrocardiogram (ECG) measurements, a task which is often computationally unfeasible due to the severe ill-posedness…

Numerical Analysis · Mathematics 2026-05-05 Edoardo Centofanti , Giovanni Ziarelli , Simone Scacchi , Luca Franco Pavarino

Remote patient monitoring based on wearable single-lead electrocardiogram (ECG) devices has significant potential for enabling the early detection of heart disease, especially in combination with artificial intelligence (AI) approaches for…

Signal Processing · Electrical Eng. & Systems 2024-04-30 Aruna Mohan , Danne Elbers , Or Zilbershot , Fatemeh Afghah , David Vorchheimer

Inverse problems can be described as limited-data problems in which the signal of interest cannot be observed directly. A physics-based forward model that relates the signal with the observations is typically needed. Unfortunately, unknown…

Signal Processing · Electrical Eng. & Systems 2025-07-08 Alexandra Koulouri , Ville Rimpilainen

Electroencephalography provides a non-invasive window into brain activity, offering valuable insights for neurological research, brain-computer interfaces, and clinical diagnostics. However, the development of robust machine learning models…

Signal Processing · Electrical Eng. & Systems 2025-02-26 Chi-Sheng Chen , Ying-Jung Chen , Aidan Hung-Wen Tsai

Cardiac arrhythmia is a prevalent and significant cause of morbidity and mortality among cardiac ailments. Early diagnosis is crucial in providing intervention for patients suffering from cardiac arrhythmia. Traditionally, diagnosis is…

Signal Processing · Electrical Eng. & Systems 2020-04-14 Sricharan Vijayarangan , Balamurali Murugesan , Vignesh R , Preejith SP , Jayaraj Joseph , Mohansankar Sivaprakasam

Interpretation of electrocardiography (ECG) signals is required for diagnosing cardiac arrhythmia. Recently, machine learning techniques have been applied for automated computer-aided diagnosis. Machine learning tasks can be divided into…

Probabilistic estimation of cardiac electrophysiological model parameters serves an important step towards model personalization and uncertain quantification. The expensive computation associated with these model simulations, however, makes…