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Analyzing the motion of multiple biological agents, be it cells or individual animals, is pivotal for the understanding of complex collective behaviors. With the advent of advanced microscopy, detailed images of complex tissue formations…

Biological Physics · Physics 2024-11-19 Masahito Uwamichi , Simon K. Schnyder , Tetsuya J. Kobayashi , Satoshi Sawai

Bayesian approaches have become increasingly popular in causal inference problems due to their conceptual simplicity, excellent performance and in-built uncertainty quantification ('posterior credible sets'). We investigate Bayesian…

Machine Learning · Statistics 2019-09-27 Kolyan Ray , Botond Szabo

Ensemble learning is a mainstay in modern data science practice. Conventional ensemble algorithms assign to base models a set of deterministic, constant model weights that (1) do not fully account for individual models' varying accuracy…

Methodology · Statistics 2019-04-02 Jeremiah Zhe Liu , John Paisley , Marianthi-Anna Kioumourtzoglou , Brent A. Coull

Optimal experimental design (OED) provides a systematic approach to quantify and maximize the value of experimental data. Under a Bayesian approach, conventional OED maximizes the expected information gain (EIG) on model parameters.…

Computation · Statistics 2026-04-08 Shijie Zhong , Wanggang Shen , Tommie Catanach , Xun Huan

Objective: We present a technique for identification and statistical analysis of quasiperiodic spatiotemporal pressure signals recorded from multiple closely spaced sensors in the human colon. Methods: Identification is achieved by…

Applications · Statistics 2019-12-06 Lukasz Wiklendt , Marcello Costa , Simon Brookes , Phil G. Dinning

Conditional Density Estimation (CDE) models deal with estimating conditional distributions. The conditions imposed on the distribution are the inputs of the model. CDE is a challenging task as there is a fundamental trade-off between model…

Machine Learning · Statistics 2018-10-31 Vincent Dutordoir , Hugh Salimbeni , Marc Deisenroth , James Hensman

Bayesian nonparametric models offer a flexible and powerful framework for statistical model selection, enabling the adaptation of model complexity to the intricacies of diverse datasets. This survey intends to delve into the significance of…

Machine Learning · Computer Science 2024-04-02 Bahman Moraffah

Often the regression function is specified by a system of ordinary differential equations (ODEs) involving some unknown parameters. Typically analytical solution of the ODEs is not available, and hence likelihood evaluation at many…

Statistics Theory · Mathematics 2016-02-23 Prithwish Bhaumik , Subhashis Ghosal

One of the goals of neuroscience is to study interactions between different brain regions during rest and while performing specific cognitive tasks. The Multivariate Bayesian Autoregressive Decomposition (MBMARD) is proposed as an intuitive…

Methodology · Statistics 2023-05-16 Guillermo Granados-Garcia , Raquel Prado , Hernando Ombao

This research proposes a flexible Bayesian extension of the composite Gaussian process (CGP) model of Ba and Joseph (2012) for predicting (stationary or) non-stationary $y(\mathbf{x})$. The CGP generalizes the regression plus stationary…

Methodology · Statistics 2019-06-27 Casey B. Davis , Christopher M. Hans , Thomas J. Santner

Analysis of heterogeneous patterns in complex spatio-temporal data finds usage across various domains in applied science and engineering, including training autonomous vehicles to navigate in complex traffic scenarios. Motivated by…

Machine Learning · Statistics 2021-02-16 Sunrit Chakraborty , Aritra Guha , Rayleigh Lei , XuanLong Nguyen

Motivated by the need to study the molecular mechanism underlying Type 1 Diabetes (T1D) with the gene expression data collected from both the patients and healthy controls at multiple time points, we propose an innovative method for jointly…

Methodology · Statistics 2018-12-10 Bochao Jia , Faming Liang , the TEDDY Study Group

Uncertainty in the prediction of future weather is commonly assessed through the use of forecast ensembles that employ a numerical weather prediction model in distinct variants. Statistical postprocessing can correct for biases in the…

Applications · Statistics 2016-06-16 Annette Möller , Thordis L. Thorarinsdottir , Alex Lenkoski , Tilmann Gneiting

Intuitive human-machine interfaces may be developed using pattern classification to estimate executed human motions from electromyogram (EMG) signals generated during muscle contraction. The continual use of EMG-based interfaces gradually…

Signal Processing · Electrical Eng. & Systems 2023-10-03 Seitaro Yoneda , Akira Furui

High-dimensional mediation analysis aims to identify mediating pathways and to estimate indirect effects linking an exposure to an outcome. In this paper, we propose a Bayesian framework to address key challenges in these analyses,…

Methodology · Statistics 2026-02-13 Youngho Bae , Chanmin Kim , Fenglei Wang , Qi Sun , Kyu Ha Lee

The estimation of patient-specific tissue properties in the form of model parameters is important for personalized physiological models. However, these tissue properties are spatially varying across the underlying anatomical model,…

Machine Learning · Statistics 2020-05-19 Jwala Dhamala , Sandesh Ghimire , John L. Sapp , B. Milan Horácek , Linwei Wang

The capture of changes in dynamic systems, especially ordinary differential equations (ODEs), is an important and challenging task, with multiple applications in biomedical research and other scientific areas. This article proposes a fast…

Applications · Statistics 2024-11-20 Yan Sun , Yeping Wang , Zhaohui Li , Shihao Yang

We present the interpretable meta neural ordinary differential equation (iMODE) method to rapidly learn generalizable (i.e., not parameter-specific) dynamics from trajectories of multiple dynamical systems that vary in their physical…

Machine Learning · Computer Science 2023-09-28 Qiaofeng Li , Tianyi Wang , Vwani Roychowdhury , M. Khalid Jawed

We propose a novel Bayesian model framework for discrete ordinal and count data based on conditional transformations of the responses. The conditional transformation function is estimated from the data in conjunction with an a priori chosen…

Methodology · Statistics 2022-05-19 Manuel Carlan , Thomas Kneib

The definition of partial differential equation (PDE) models usually involves a set of parameters whose values may vary over a wide range. The solution of even a single set of parameter values may be quite expensive. In many cases, e.g.,…

Numerical Analysis · Mathematics 2016-11-17 Max Gunzburger , Nan Jiang , Michael Schneier