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Alzheimer's disease affects over 55 million people worldwide and is projected to more than double by 2050, necessitating rapid, accurate, and scalable diagnostics. However, existing approaches are limited because they cannot achieve…

Computer Vision and Pattern Recognition · Computer Science 2025-07-29 Ahmed Sharshar , Yasser Ashraf , Tameem Bakr , Salma Hassan , Hosam Elgendy , Mohammad Yaqub , Mohsen Guizani

In medical vision, different imaging modalities provide complementary information. However, in practice, not all modalities may be available during inference or even training. Previous approaches, e.g., knowledge distillation or image…

Computer Vision and Pattern Recognition · Computer Science 2023-08-23 Aishik Konwer , Xiaoling Hu , Joseph Bae , Xuan Xu , Chao Chen , Prateek Prasanna

Multimodal magnetic resonance imaging (MRI) constitutes the first line of investigation for clinicians in the care of brain tumors, providing crucial insights for surgery planning, treatment monitoring, and biomarker identification.…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Lucas Robinet , Ahmad Berjaoui , Elizabeth Cohen-Jonathan Moyal

Automated incident management is critical for microservice reliability. While recent unified frameworks leverage multimodal data for joint optimization, they unrealistically assume perfect data completeness. In practice, network…

Machine Learning · Computer Science 2026-03-30 Wenzhuo Qian , Hailiang Zhao , Ziqi Wang , Zhipeng Gao , Jiayi Chen , Zhiwei Ling , Shuiguang Deng

Cognitive decline is highly heterogeneous across individuals, which complicates prognosis, trial design, and treatment planning. We present the Personalized Cognitive Decline Assessment Digital Twin (PCD-DT), a multimodal and…

Artificial Intelligence · Computer Science 2026-05-01 Bulent Soykan , Gulsah Hancerliogullari Koksalmis , Hsin-Hsiung Huang , Laura J. Brattain

Multimodal learning, which integrates data from diverse sensory modes, plays a pivotal role in artificial intelligence. However, existing multimodal learning methods often struggle with challenges where some modalities appear more dominant…

Machine Learning · Computer Science 2024-04-02 Xiaohui Zhang , Jaehong Yoon , Mohit Bansal , Huaxiu Yao

Multimodal Sentiment Analysis (MSA) seeks to understand human emotions by integrating textual, acoustic, and visual signals. Although multimodal fusion is designed to leverage cross-modal complementarity, real-world scenarios often exhibit…

Machine Learning · Computer Science 2025-11-26 Kang He , Boyu Chen , Yuzhe Ding , Fei Li , Chong Teng , Donghong Ji

Multimodal learning seeks to combine data from multiple input sources to enhance the performance of different downstream tasks. In real-world scenarios, performance can degrade substantially if some input modalities are missing. Existing…

Machine Learning · Computer Science 2024-10-10 Niki Nezakati , Md Kaykobad Reza , Ameya Patil , Mashhour Solh , M. Salman Asif

Alzheimer disease (AD) diagnosis and prognosis increasingly rely on machine learning (ML) models. Although these models provide good results, clinical adoption is limited by the need for technical expertise and the lack of trustworthy and…

Machine Learning · Computer Science 2026-03-11 Pablo Guillén , Enrique Frias-Martinez

Multimodal language models now integrate text, audio, and video for unified reasoning. Yet existing RL post-training pipelines treat all input signals as equally relevant, ignoring which modalities each task actually requires. This…

Artificial Intelligence · Computer Science 2026-02-13 Nikhil Verma , Minjung Kim , JooYoung Yoo , Kyung-Min Jin , Manasa Bharadwaj , Kevin Ferreira , Ko Keun Kim , Youngjoon Kim

Alzheimer's Disease (AD) is a progressive neurological disorder that can result in significant cognitive impairment and dementia. Accurate and timely diagnosis is essential for effective treatment and management of this disease. In this…

Image and Video Processing · Electrical Eng. & Systems 2024-12-10 Mozhgan Naderi , Maryam Rastgarpour , Amir Reza Takhsha

Omni-modal large language models (omni LLMs) have recently achieved strong performance across audiovisual understanding tasks, yet they remain highly susceptible to cross-modal hallucinations arising from spurious correlations and dominant…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Ashutosh Chaubey , Jiacheng Pang , Mohammad Soleymani

Multi-view or even multi-modal data is appealing yet challenging for real-world applications. Detecting anomalies in multi-view data is a prominent recent research topic. However, most of the existing methods 1) are only suitable for two…

Machine Learning · Computer Science 2023-11-02 Hao Wang , Zhi-Qi Cheng , Jingdong Sun , Xin Yang , Xiao Wu , Hongyang Chen , Yan Yang

Neurobiological and neurodegenerative diseases are inherently multifactorial, arising from coupled influences spanning genetic susceptibility, brain alterations, and environmental and behavioral factors. Multimodal modeling has therefore…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Shaowen Wan , Yanjun Lv , Lu Zhang , Dajiang Zhu , Bharat Biswal , Tianming Liu , Xiaobo Li , Lin Zhao

Alzheimer's disease (AD) is a growing global health challenge as populations age, and timely, accurate diagnosis is essential to reduce individual and societal burden. However, real-world AD assessment is hampered by incomplete,…

Alzheimer's disease (AD) is an incurable neurodegenerative condition leading to cognitive and functional deterioration. Given the lack of a cure, prompt and precise AD diagnosis is vital, a complex process dependent on multiple factors and…

Computer Vision and Pattern Recognition · Computer Science 2024-03-26 Guangqian Yang , Kangrui Du , Zhihan Yang , Ye Du , Yongping Zheng , Shujun Wang

A mediation analysis approach is proposed for multiple exposures, multiple mediators, and a continuous scalar outcome under the linear structural equation modeling framework. It assumes that there exist orthogonal components that…

Methodology · Statistics 2022-09-12 Yi Zhao

Alzheimer's disease is estimated to affect around 50 million people worldwide and is rising rapidly, with a global economic burden of nearly a trillion dollars. This calls for scalable, cost-effective, and robust methods for detection of…

Audio and Speech Processing · Electrical Eng. & Systems 2020-09-03 Utkarsh Sarawgi , Wazeer Zulfikar , Nouran Soliman , Pattie Maes

Multimodal physiological data powers clinical AI systems from intensive care units to wearable devices, but sensors routinely fail in practice. Two failure modes are common: modality missing, where an entire channel is absent, and…

Machine Learning · Computer Science 2026-05-18 Wugeng Zheng , Ziwen Kan , Tianlong Chen , Chen Chen , Song Wang

Early and reliable detection of Alzheimer's disease (AD) is crucial for timely clinical intervention and improved patient management. It also supports the evaluation of emerging therapeutic strategies. In this paper, we propose a Low-Rank…

Machine Learning · Computer Science 2026-05-07 Wu Wang , Yuang Cheng , Fouzi Harrou , Ying Sun
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