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Risk thresholds provide a measure of the level of risk exposure that a society or individual is willing to withstand, ultimately shaping how we determine the safety of technological systems. Against the backdrop of the Cold War, the first…

Computers and Society · Computer Science 2025-04-22 Heidy Khlaaf , Sarah Myers West

The rapid growth of Artificial Intelligence (AI) in healthcare has sparked interest in Trustworthy AI and AI Implementation Science, both of which are essential for accelerating clinical adoption. However, strict regulations, gaps between…

Quantitative Methods · Quantitative Biology 2026-03-06 Benoit L. Marteau , Andrew Hornback , Shaun Q. Tan , Christian Lowson , Jason Woloff , May D. Wang

Generative AI systems achieve impressive performance on standard benchmarks yet fail to deliver real-world utility, a disconnect we identify across 28 deployment cases spanning education, healthcare, software engineering, and law. We argue…

Machine Learning · Computer Science 2026-05-12 Ishani Mondal , Shweta Bhardwaj

As the deployment of Artificial Intelligence (AI) systems in high-stakes sectors - like healthcare, finance, education, justice, and infrastructure has increased - the possibility and impact of failures of these systems have significantly…

Cryptography and Security · Computer Science 2025-08-28 Aoun E Muhammad , Kin Choong Yow , Jamel Baili , Yongwon Cho , Yunyoung Nam

Artificial intelligence (AI) is increasingly being used to augment and automate cyber operations, altering the scale, speed, and accessibility of malicious activity. These shifts raise urgent questions about when AI systems introduce…

Cryptography and Security · Computer Science 2026-01-27 Krystal Jackson , Deepika Raman , Jessica Newman , Nada Madkour , Charlotte Yuan , Evan R. Murphy

Existing benchmarks for LLM-based vulnerability detection compress model performance into a single metric, which fails to reflect the distinct priorities of different stakeholders. For example, a CISO may emphasize high recall of critical…

Cryptography and Security · Computer Science 2026-04-03 Subho Halder , Siddharth Saxena , Kashinath Kadaba Shrish , Thiyagarajan M

Responsible Artificial Intelligence (RAI) addresses the ethical and regulatory challenges of deploying AI systems in high-risk scenarios. This paper proposes a comprehensive framework for the design of an RAI system (RAIS) that integrates…

Following the AI Seoul Summit in 2024, twelve AI companies published frontier AI safety frameworks (Frameworks) outlining their approaches to managing catastrophic risks from advanced AI systems. Emerging legislation increasingly treats…

Computers and Society · Computer Science 2026-05-01 Lily Stelling , Malcolm Murray , Bruno Galizzi , Max Schaffelder , Siméon Campos , Henry Papadatos

As artificial intelligence (AI) systems approach and surpass expert human performance across a broad range of tasks, obtaining high-quality human supervision for evaluation and training becomes increasingly challenging. Our focus is on…

Machine Learning · Computer Science 2026-02-25 Ren Yin , Takashi Ishida , Masashi Sugiyama

Large Language Models (LLMs) have shown impressive potential in clinical question answering (QA), with Retrieval Augmented Generation (RAG) emerging as a leading approach for ensuring the factual accuracy of model responses. However,…

Computation and Language · Computer Science 2025-07-21 Mohita Chowdhury , Yajie Vera He , Jared Joselowitz , Aisling Higham , Ernest Lim

InvisibleBench is a deployment gate for caregiving-relationship AI, evaluating 3-20+ turn interactions across five dimensions: Safety, Compliance, Trauma-Informed Design, Belonging/Cultural Fitness, and Memory. The benchmark includes…

Computers and Society · Computer Science 2025-11-27 Ali Madad

Current approaches to AI safety define red lines at the case level: specific prompts, specific outputs, specific harms. This paper argues that red lines can be set more fundamentally -- at the level of value, evidence, and source…

Artificial Intelligence · Computer Science 2026-04-14 Seulki Lee

As AI-based clinical decision support (AI-CDS) is introduced in more and more aspects of healthcare services, HCI research plays an increasingly important role in designing for complementarity between AI and clinicians. However, current…

Human-Computer Interaction · Computer Science 2025-04-11 Venkatesh Sivaraman , Katelyn Morrison , Will Epperson , Adam Perer

Large healthcare institutions typically operate multiple business intelligence (BI) teams segmented by domain, including clinical performance, fundraising, operations, and compliance. Due to HIPAA, FERPA, and IRB restrictions, these teams…

Machine Learning · Computer Science 2026-03-10 Mohammed Omer Shakeel Ahmed

Artificial intelligence systems are increasingly deployed in biomedical research. However, current evaluation frameworks may inadequately assess their effectiveness as research collaborators. This rapid review examines benchmarking…

AI companions powered by large language models (LLMs) are increasingly integrated into users' daily lives, offering emotional support and companionship. While existing safety systems focus on overt harms, they rarely address early-stage…

Human-Computer Interaction · Computer Science 2025-10-21 Ziv Ben-Zion , Paul Raffelhüschen , Max Zettl , Antonia Lüönd , Achim Burrer , Philipp Homan , Tobias R Spiller

Ensuring fairness in AI systems is critical, especially in high-stakes domains such as lending, hiring, and healthcare. This urgency is reflected in emerging global regulations that mandate fairness assessments and independent bias audits.…

Machine Learning · Computer Science 2025-08-19 Varsha Ramineni , Hossein A. Rahmani , Emine Yilmaz , David Barber

The rapid expansion of large language model (LLM) safety evaluation has produced a substantial benchmark ecosystem, but not a correspondingly coherent measurement ecosystem. We present AISafetyBenchExplorer, a structured catalogue of 195 AI…

Artificial Intelligence · Computer Science 2026-04-24 Abiodun A. Solanke

As frontier AI systems advance toward transformative capabilities, we need a parallel transformation in how we measure and evaluate these systems to ensure safety and inform governance. While benchmarks have been the primary method for…

Artificial Intelligence · Computer Science 2025-05-12 Markov Grey , Charbel-Raphaël Segerie

The potential presented by Artificial Intelligence (AI) for healthcare has long been recognised by the technical community. More recently, this potential has been recognised by policymakers, resulting in considerable public and private…

Artificial Intelligence · Computer Science 2021-04-15 Jessica Morley , Caroline Morton , Kassandra Karpathakis , Mariarosaria Taddeo , Luciano Floridi