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Clinical trials are critical for drug development. Constructing the appropriate eligibility criteria (i.e., the inclusion/exclusion criteria for patient recruitment) is essential for the trial's success. Proper design of clinical trial…

Computation and Language · Computer Science 2023-10-10 Zifeng Wang , Cao Xiao , Jimeng Sun

Recent years have seen particular interest in using electronic medical records (EMRs) for secondary purposes to enhance the quality and safety of healthcare delivery. EMRs tend to contain large amounts of valuable clinical notes. Learning…

Computation and Language · Computer Science 2022-07-25 Hoda Memarzadeh , Nasser Ghadiri , Maryam Lotfi Shahreza

Clinical outcome prediction based on the Electronic Health Record (EHR) plays a crucial role in improving the quality of healthcare. Conventional deep sequential models fail to capture the rich temporal patterns encoded in the longand…

Machine Learning · Computer Science 2019-08-27 Luchen Liu , Haoran Li , Zhiting Hu , Haoran Shi , Zichang Wang , Jian Tang , Ming Zhang

A long-running goal of the clinical NLP community is the extraction of important variables trapped in clinical notes. However, roadblocks have included dataset shift from the general domain and a lack of public clinical corpora and…

Computation and Language · Computer Science 2022-12-01 Monica Agrawal , Stefan Hegselmann , Hunter Lang , Yoon Kim , David Sontag

Medical consultation dialogues contain critical clinical information, yet their unstructured nature hinders effective utilization in diagnosis and treatment. Traditional methods, relying on rule-based or shallow machine learning techniques,…

Computation and Language · Computer Science 2025-04-24 Shuguang Zhao , Qiangzhong Feng , Zhiyang He , Peipei Sun , Yingying Wang , Xiaodong Tao , Xiaoliang Lu , Mei Cheng , Xinyue Wu , Yanyan Wang , Wei Liang

Long-term adherence to medication is a critical factor in preventing chronic diseases, such as cardiovascular disease. To address poor adherence, physicians may recommend adherence-improving interventions; however, such interventions are…

Optimization and Control · Mathematics 2026-02-24 Daniel Otero-Leon , Mariel Lavieri , Brian Denton , Jeremy Sussman , Rodney Hayward

The MEDIQA-CORR 2024 shared task aims to assess the ability of Large Language Models (LLMs) to identify and correct medical errors in clinical notes. In this study, we evaluate the capability of general LLMs, specifically GPT-3.5 and GPT-4,…

Computation and Language · Computer Science 2024-05-29 Aryo Pradipta Gema , Chaeeun Lee , Pasquale Minervini , Luke Daines , T. Ian Simpson , Beatrice Alex

Humans perceive discrete events such as "restaurant visits" and "train rides" in their continuous experience. One important prerequisite for studying human event perception is the ability of researchers to quantify when one event ends and…

Computation and Language · Computer Science 2023-01-26 Sebastian Michelmann , Manoj Kumar , Kenneth A. Norman , Mariya Toneva

Accurate prediction of clinical outcomes using Electronic Health Records (EHRs) is critical for early intervention, efficient resource allocation, and improved patient care. EHRs contain multimodal data, including both structured data and…

Machine Learning · Computer Science 2025-08-29 Rituparna Datta , Jiaming Cui , Zihan Guan , Vishal G. Reddy , Joshua C. Eby , Gregory Madden , Rupesh Silwal , Anil Vullikanti

Recently, pretrained language models based on BERT have been introduced for the French biomedical domain. Although these models have achieved state-of-the-art results on biomedical and clinical NLP tasks, they are constrained by a limited…

Computation and Language · Computer Science 2024-02-27 Adrien Bazoge , Emmanuel Morin , Beatrice Daille , Pierre-Antoine Gourraud

Automatic International Classification of Diseases (ICD) coding aims to assign multiple ICD codes to a medical note with average length of 3,000+ tokens. This task is challenging due to a high-dimensional space of multi-label assignment…

Computation and Language · Computer Science 2022-10-14 Zhichao Yang , Shufan Wang , Bhanu Pratap Singh Rawat , Avijit Mitra , Hong Yu

We investigate how agents built on pretrained large language models (LLMs) can learn target classification functions from labeled examples without parameter updates. While conventional approaches like fine-tuning are often costly,…

Computation and Language · Computer Science 2026-05-06 Jackson Hassell , Dan Zhang , Hannah Kim , Tom Mitchell , Estevam Hruschka

The utilization of Electronic Health Records (EHRs) for clinical risk prediction is on the rise. However, strict privacy regulations limit access to comprehensive health records, making it challenging to apply standard machine learning…

Computation and Language · Computer Science 2023-12-08 Angeela Acharya , Sulabh Shrestha , Anyi Chen , Joseph Conte , Sanja Avramovic , Siddhartha Sikdar , Antonios Anastasopoulos , Sanmay Das

Large vision-language models (VLMs) have evolved from general-purpose applications to specialized use cases such as in the clinical domain, demonstrating potential for decision support in radiology. One promising application is assisting…

Computer Vision and Pattern Recognition · Computer Science 2026-02-25 Zhifan Jiang , Dong Yang , Vishwesh Nath , Abhijeet Parida , Nishad P. Kulkarni , Ziyue Xu , Daguang Xu , Syed Muhammad Anwar , Holger R. Roth , Marius George Linguraru

The advent of the Internet era has led to an explosive growth in the Electronic Health Records (EHR) in the past decades. The EHR data can be regarded as a collection of clinical events, including laboratory results, medication records,…

Machine Learning · Computer Science 2019-11-14 Zichang Wang , Haoran Li , Luchen Liu , Haoxian Wu , Ming Zhang

With the rise of medical foundation models and the growing availability of imaging data, scalable pretraining techniques offer a promising way to identify imaging biomarkers predictive of future disease risk. While current self-supervised…

Heart failure hospitalization is a severe burden on healthcare. How to predict and therefore prevent readmission has been a significant challenge in outcomes research. To address this, we propose a deep learning approach to predict…

Computation and Language · Computer Science 2019-12-24 Xiong Liu , Yu Chen , Jay Bae , Hu Li , Joseph Johnston , Todd Sanger

Writing clinical notes and documenting medical exams is a critical task for healthcare professionals, serving as a vital component of patient care documentation. However, manually writing these notes is time-consuming and can impact the…

Computation and Language · Computer Science 2025-06-17 Yizhan Li , Sifan Wu , Christopher Smith , Thomas Lo , Bang Liu

Prediction of medical codes from clinical notes is a practical and essential need for every healthcare delivery organization within current medical systems. Automating annotation will save significant time and excessive effort that human…

Machine Learning · Computer Science 2022-11-01 Byung-Hak Kim

Although machine learning has become a powerful tool to augment doctors in clinical analysis, the immense amount of labeled data that is necessary to train supervised learning approaches burdens each development task as time and resource…