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Related papers: Training Large Language Models to Predict Clinical…

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This paper proposes a forecast-centric adaptive learning model that engages with the past studies on the order book and high-frequency data, with applications to hypothesis testing. In line with the past literature, we produce brackets of…

Statistical Finance · Quantitative Finance 2021-03-02 Parley Ruogu Yang

Large language models are trained in two stages: (1) unsupervised pretraining from raw text, to learn general-purpose representations, and (2) large scale instruction tuning and reinforcement learning, to better align to end tasks and user…

Computation and Language · Computer Science 2023-05-22 Chunting Zhou , Pengfei Liu , Puxin Xu , Srini Iyer , Jiao Sun , Yuning Mao , Xuezhe Ma , Avia Efrat , Ping Yu , Lili Yu , Susan Zhang , Gargi Ghosh , Mike Lewis , Luke Zettlemoyer , Omer Levy

The Large Scale Visual Recognition Challenge based on the well-known Imagenet dataset catalyzed an intense flurry of progress in computer vision. Benchmark tasks have propelled other sub-fields of machine learning forward at an equally…

Machine Learning · Computer Science 2020-10-06 David Bellamy , Leo Celi , Andrew L. Beam

Healthcare providers usually record detailed notes of the clinical care delivered to each patient for clinical, research, and billing purposes. Due to the unstructured nature of these narratives, providers employ dedicated staff to assign…

Computation and Language · Computer Science 2022-08-03 Chufan Gao , Mononito Goswami , Jieshi Chen , Artur Dubrawski

Large language models (LLMs) have recently showcased remarkable capabilities, spanning a wide range of tasks and applications, including those in the medical domain. Models like GPT-4 excel in medical question answering but may face…

Computation and Language · Computer Science 2025-07-02 Bowen Wang , Jiuyang Chang , Yiming Qian , Guoxin Chen , Junhao Chen , Zhouqiang Jiang , Jiahao Zhang , Yuta Nakashima , Hajime Nagahara

Machine learning systems show significant promise for forecasting patient adverse events via risk scores. However, these risk scores implicitly encode assumptions about future interventions that the patient is likely to receive, based on…

Clinical event sequences consist of thousands of clinical events that represent records of patient care in time. Developing accurate prediction models for such sequences is of a great importance for defining representations of a patient…

Machine Learning · Computer Science 2021-04-07 Jeong Min Lee , Milos Hauskrecht

When training clinical prediction models from electronic health records (EHRs), a key concern should be a model's ability to sustain performance over time when deployed, even as care practices, database systems, and population demographics…

Clinical prediction is an essential task in the healthcare industry. However, the recent success of transformers, on which large language models are built, has not been extended to this domain. In this research, we explore the use of…

Computation and Language · Computer Science 2023-05-08 Zekai Chen , Mariann Micsinai Balan , Kevin Brown

$\textbf{Objective}$ Develop an automatic diagnostic system which only uses textual admission information from Electronic Health Records (EHRs) and assist clinicians with a timely and statistically proved decision tool. The hope is that the…

Computation and Language · Computer Science 2017-12-08 Christy Li , Dimitris Konomis , Graham Neubig , Pengtao Xie , Carol Cheng , Eric Xing

Large-scale pretraining has transformed modeling of language and other data types, but its potential remains underexplored in healthcare with structured electronic health records (EHRs). We present a novel generative pretraining strategy…

Large Language Models have revolutionized various fields and industries, such as Conversational AI, Content Generation, Information Retrieval, Business Intelligence, and Medical, to name a few. One major application in the field of medical…

Computation and Language · Computer Science 2024-02-06 Ata Mustafa

Large clinical datasets derived from insurance claims and electronic health record (EHR) systems are valuable sources for precision medicine research. These datasets can be used to develop models for personalized prediction of risk or…

Methodology · Statistics 2021-10-20 Liang Liang , Jue Hou , Hajime Uno , Kelly Cho , Yanyuan Ma , Tianxi Cai

In healthcare, the emphasis on patient safety and the minimization of medical errors cannot be overstated. Despite concerted efforts, many healthcare systems, especially in low-resource regions, still grapple with preventing these errors…

Computation and Language · Computer Science 2023-12-21 M Tran , C Sun

The shift to electronic medical records (EMRs) has engendered research into machine learning and natural language technologies to analyze patient records, and to predict from these clinical outcomes of interest. Two observations motivate…

Computation and Language · Computer Science 2019-04-09 Sarthak Jain , Ramin Mohammadi , Byron C. Wallace

Large Language Models (LLMs) have demonstrated substantial progress in biomedical and clinical applications, motivating rigorous evaluation of their ability to answer nuanced, evidence-based questions. We curate a multi-source benchmark…

Computation and Language · Computer Science 2025-09-16 Can Wang , Yiqun Chen

Although recent advances in scaling large language models (LLMs) have resulted in improvements on many NLP tasks, it remains unclear whether these models trained primarily with general web text are the right tool in highly specialized,…

Large language models (LLMs) excel at text generation, but their ability to handle clinical classification tasks involving structured data, such as time series, remains underexplored. In this work, we adapt instruction-tuned LLMs using…

Computation and Language · Computer Science 2025-09-18 Iyadh Ben Cheikh Larbi , Ajay Madhavan Ravichandran , Aljoscha Burchardt , Roland Roller

The ability to predict drug overdose risk from a patient's medical records is crucial for timely intervention and prevention. Traditional machine learning models have shown promise in analyzing longitudinal medical records for this task.…

Artificial Intelligence · Computer Science 2025-04-17 Md Sultan Al Nahian , Chris Delcher , Daniel Harris , Peter Akpunonu , Ramakanth Kavuluru

Recent works on large language models (LLMs) have demonstrated the impact of prompting strategies and fine-tuning techniques on their reasoning capabilities. Yet, their effectiveness on clinical natural language inference (NLI) remains…

Computation and Language · Computer Science 2025-07-08 Mael Jullien , Marco Valentino , Leonardo Ranaldi , Andre Freitas
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