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Self-supervised representation learning often relies on deterministic predictive architectures to align context and target views in latent space. While effective in many settings, such methods are limited in genuinely multi-modal inverse…

Machine Learning · Computer Science 2026-03-31 Yongchao Huang

SMILES-based molecular generative models have been pivotal in drug design but face challenges in fragment-constrained tasks. To address this, the Sequential Attachment-based Fragment Embedding (SAFE) representation was recently introduced…

Machine Learning · Computer Science 2024-10-29 Yassir El Mesbahi , Emmanuel Noutahi

Estimating racial disparity requires individual-level race data, which are often unavailable due to the sensitivity of collecting such information. To address this problem, many researchers utilize Bayesian Improved Surname Geocoding…

Computation and Language · Computer Science 2026-04-29 Noah Dasanaike , Kosuke Imai

The rise of graph-structured data has driven major advances in Graph Machine Learning (GML), where graph embeddings (GEs) map features from Knowledge Graphs (KGs) into vector spaces, enabling tasks like node classification and link…

Machine Learning · Computer Science 2026-01-27 Rosario Napoli , Gabriele Morabito , Antonio Celesti , Massimo Villari , Maria Fazio

The fast and affordable sequencing of large clinical and environmental metagenomic datasets opens up new horizons in medical and biotechnological applications. It is believed that today we have described only about 1\% of the microorganisms…

Genomics · Quantitative Biology 2017-10-31 Balazs Szalkai , Vince Grolmusz

Mobile edge generation (MEG) is an emerging technology that allows the network to meet the challenging traffic load expectations posed by the rise of generative artificial intelligence~(GAI). A novel MEG model is proposed for deploying GAI…

Information Theory · Computer Science 2024-09-11 Ruikang Zhong , Xidong Mu , Mona Jaber , Yuanwei Liu

Biological sequence analysis is an essential step toward building a deeper understanding of the underlying functions, structures, and behaviors of the sequences. It can help in identifying the characteristics of the associated organisms,…

Machine Learning · Computer Science 2023-03-07 Taslim Murad , Sarwan Ali , Murray Patterson

Discrete data such as counts of microbiome taxa resulting from next-generation sequencing are routinely encountered in bioinformatics. Taxa count data in microbiome studies are typically high-dimensional, over-dispersed, and can only reveal…

Methodology · Statistics 2022-06-23 Yuan Fang , Sanjeena Subedi

Co-occurrence network inference algorithms have significantly advanced our understanding of microbiome communities. However, these algorithms typically analyze microbial associations within samples collected from a single environmental…

Machine Learning · Computer Science 2025-10-15 Daniel Agyapong , Briana H. Beatty , Peter G. Kennedy , Jane C. Marks , Toby D. Hocking

Low-dimensional embeddings of nodes in large graphs have proved extremely useful in a variety of prediction tasks, from content recommendation to identifying protein functions. However, most existing approaches require that all nodes in the…

Social and Information Networks · Computer Science 2018-09-11 William L. Hamilton , Rex Ying , Jure Leskovec

In sequence-based predictions, conventionally an input sequence is represented by a multiple sequence alignment (MSA) or a representation derived from MSA, such as a position-specific scoring matrix. Recently, inspired by the development in…

Quantitative Methods · Quantitative Biology 2021-10-18 Nabil Ibtehaz , Daisuke Kihara

Sparse generalized matrix-matrix multiplication (SpGEMM) is a fundamental operation for real-world network analysis. With the increasing size of real-world networks, the single-machine-based SpGEMM approach cannot perform SpGEMM on…

Data Structures and Algorithms · Computer Science 2023-08-29 Myung-Hwan Jang , Yunyong Ko , Hyuck-Moo Gwon , Ikhyeon Jo , Yongjun Park , Sang-Wook Kim

Unsupervised attributed graph representation learning is challenging since both structural and feature information are required to be represented in the latent space. Existing methods concentrate on learning latent representation via…

Machine Learning · Computer Science 2021-04-28 Zelin Zang , Siyuan Li , Di Wu , Jianzhu Guo , Yongjie Xu , Stan Z. Li

Accurate identification of protein-nucleotide binding sites is fundamental to deciphering molecular mechanisms and accelerating drug discovery. However, current computational methods often struggle with suboptimal performance due to…

Machine Learning · Computer Science 2026-03-17 Yiming Gao , Liuyi Xu , Pengshan Cui , Yining Qian , An-Yang Lu , Xianpeng Wang

Metagenomics characterizes microbial communities by random shotgun sequencing of DNA isolated directly from an environment of interest. An essential step in computational metagenome analysis is taxonomic sequence assignment, which allows us…

Genomics · Quantitative Biology 2014-04-04 J. Dröge , I. Gregor , A. C. McHardy

There is a growing awareness of the important roles that microbial communities play in complex biological processes. Modern investigation of these often uses next generation sequencing of metagenomic samples to determine community…

Applications · Statistics 2018-01-25 Adrian Dobra , Camilo Valdes , Dragana Ajdic , Bertrand Clarke , Jennifer Clarke

Network embedding aims at projecting the network data into a low-dimensional feature space, where the nodes are represented as a unique feature vector and network structure can be effectively preserved. In recent years, more and more online…

Social and Information Networks · Computer Science 2017-11-28 Jiawei Zhang , Congying Xia , Chenwei Zhang , Limeng Cui , Yanjie Fu , Philip S. Yu

The increasing availability and accessibility of numerous overhead images allows us to estimate and assess the spatial arrangement of groups of geospatial target objects, which can benefit many applications, such as traffic monitoring and…

Computer Vision and Pattern Recognition · Computer Science 2021-12-14 Weiwei Duan , Yao-Yi Chiang , Stefan Leyk , Johannes H. Uhl , Craig A. Knoblock

Image steganography is the art of hiding secret message in grayscale or color images. Easy detection of secret message for any state-of-art image steganography can break the stego system. To prevent the breakdown of the stego system data is…

Multimedia · Computer Science 2022-01-05 Soumendu Chakraborty , Anand Singh Jalal , Charul Bhatnagar

Metagenomic studies have primarily relied on de novo assembly for reconstructing genes and genomes from microbial mixtures. While reference-guided approaches have been employed in the assembly of single organisms, they have not been used in…

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