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Recently, there has been a surging interest in using large language models (LLMs) for Verilog code generation. However, the existing approaches are limited in terms of the quality of the generated Verilog code. To address such limitations,…

Machine Learning · Computer Science 2024-10-08 Bardia Nadimi , Hao Zheng

Large vision-language models (LVLMs) have made substantial advances in reasoning tasks at the Olympiad level. Nevertheless, current Olympiad-level multimodal reasoning benchmarks for these models often emphasize single-image analysis and…

Computer Vision and Pattern Recognition · Computer Science 2026-04-23 Qiguang Chen , Chengyu Luan , Jiajun Wu , Qiming Yu , Yi Yang , Yizhuo Li , Jingqi Tong , Xiachong Feng , Libo Qin , Wanxiang Che

Building on the success of large language models (LLMs), recent advancements such as GPT-4o have enabled real-time speech interactions through LLM-based voice assistants, offering a significantly improved user experience compared to…

Computation and Language · Computer Science 2024-12-12 Yiming Chen , Xianghu Yue , Chen Zhang , Xiaoxue Gao , Robby T. Tan , Haizhou Li

Modern Protein Language Models (PLMs) apply transformer-based model architectures from natural language processing to biological sequences, predicting a variety of protein functions and properties. However, protein language has key…

Machine Learning · Computer Science 2026-02-25 Anna Hart , Chi Han , Jeonghwan Kim , Huimin Zhao , Heng Ji

Real-time human perception is crucial for effective human-robot interaction (HRI). Large vision-language models (VLMs) offer promising generalizable perceptual capabilities but often suffer from high latency, which negatively impacts user…

Large Vision-Language Models (LVLMs) have demonstrated outstanding performance across various multimodal tasks. However, they suffer from a problem known as language prior, where responses are generated based solely on textual patterns…

Artificial Intelligence · Computer Science 2025-02-11 Kang-il Lee , Minbeom Kim , Seunghyun Yoon , Minsung Kim , Dongryeol Lee , Hyukhun Koh , Kyomin Jung

This paper aims to retrieve proteins with similar structures and semantics from large-scale protein dataset, facilitating the functional interpretation of protein structures derived by structural determination methods like cryo-Electron…

Biomolecules · Quantitative Biology 2025-06-11 Qifeng Wu , Zhengzhe Liu , Han Zhu , Yizhou Zhao , Daisuke Kihara , Min Xu

The impact of Transformer-based language models has been unprecedented in Natural Language Processing (NLP). The success of such models has also led to their adoption in other fields including bioinformatics. Taking this into account, this…

Machine Learning · Computer Science 2025-07-21 Nimisha Ghosh , Daniele Santoni , Debaleena Nawn , Eleonora Ottaviani , Giovanni Felici

In the real world, a molecule is a 3D geometric structure. Compared to 1D SMILES sequences and 2D molecular graphs, 3D molecules represent the most informative molecular modality. Despite the rapid progress of autoregressive-based language…

Computational Engineering, Finance, and Science · Computer Science 2025-08-15 Lei Jiang , Shuzhou Sun , Biqing Qi , Yuchen Fu , Xiaohua Xu , Yuqiang Li , Dongzhan Zhou , Tianfan Fu

Identification of protein-protein interactions (PPIs) helps derive cellular mechanistic understanding, particularly in the context of complex conditions such as neurodegenerative disorders, metabolic syndromes, and cancer. Large Language…

Machine Learning · Computer Science 2025-08-18 Sanket Jantre , Tianle Wang , Gilchan Park , Kriti Chopra , Nicholas Jeon , Xiaoning Qian , Nathan M. Urban , Byung-Jun Yoon

We present a benchmark targeting a novel class of systems: semantic query processing engines. Those systems rely inherently on generative and reasoning capabilities of state-of-the-art large language models (LLMs). They extend SQL with…

Emotion understanding is critical for making Large Language Models (LLMs) more general, reliable, and aligned with humans. Art conveys emotion through the joint design of visual and auditory elements, yet most prior work is human-centered…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Dengming Zhang , Weitao You , Jingxiong Li , Weishen Lin , Wenda Shi , Xue Zhao , Heda Zuo , Junxian Wu , Lingyun Sun

Vision-Language Models (VLMs) have achieved remarkable progress across tasks such as visual question answering and image captioning. Yet, the extent to which these models perform visual reasoning as opposed to relying on linguistic priors…

Computer Vision and Pattern Recognition · Computer Science 2025-12-25 Brigitta Malagurski Törtei , Yasser Dahou , Ngoc Dung Huynh , Wamiq Reyaz Para , Phúc H. Lê Khac , Ankit Singh , Sofian Chaybouti , Sanath Narayan

Visually linking matching cues is a crucial ability in daily life, such as identifying the same person in multiple photos based on their cues, even without knowing who they are. Despite the extensive knowledge that vision-language models…

Computation and Language · Computer Science 2025-07-03 Jianshu Zhang , Dongyu Yao , Renjie Pi , Paul Pu Liang , Yi R. Fung

Large language models (LLMs) show significant potential in healthcare, prompting numerous benchmarks to evaluate their capabilities. However, concerns persist regarding the reliability of these benchmarks, which often lack clinical…

Computation and Language · Computer Science 2026-04-30 Wenting Chen , Guo Yu , Yiu-Fai Cheung , Meidan Ding , Jie Liu , Zizhan Ma , Wenxuan Wang , Linlin Shen

The motif-scaffolding problem is a central task in computational protein design: Given the coordinates of atoms in a geometry chosen to confer a desired biochemical function (a motif), the task is to identify diverse protein structures…

Machine Learning · Computer Science 2025-02-20 Zhuoqi Zheng , Bo Zhang , Kieran Didi , Kevin K. Yang , Jason Yim , Joseph L. Watson , Hai-Feng Chen , Brian L. Trippe

Protein Language Models (PLMs), pre-trained on extensive evolutionary data from natural proteins, have emerged as indispensable tools for protein design. While powerful, PLMs often struggle to produce proteins with precisely specified…

Biomolecules · Quantitative Biology 2025-09-15 Long-Kai Huang , Rongyi Zhu , Bing He , Jianhua Yao

Design studies aim to create visualization solutions for real-world problems of different application domains. Recently, the emergence of large language models (LLMs) has introduced new opportunities to enhance the design study process,…

Human-Computer Interaction · Computer Science 2025-08-14 Shaolun Ruan , Rui Sheng , Xiaolin Wen , Jiachen Wang , Tianyi Zhang , Yong Wang , Tim Dwyer , Jiannan Li

Recent years have witnessed a surge in the development of protein structural tokenization methods, which chunk protein 3D structures into discrete or continuous representations. Structure tokenization enables the direct application of…

Quantitative Methods · Quantitative Biology 2025-06-26 Xinyu Yuan , Zichen Wang , Marcus Collins , Huzefa Rangwala

The rapid advancement of Large Language Models (LLMs) has outpaced traditional evaluation methods. Static benchmarks fail to capture the depth and breadth of LLM capabilities and eventually become obsolete, while most dynamic approaches…

Artificial Intelligence · Computer Science 2025-04-11 Vahid Majdinasab , Amin Nikanjam , Foutse Khomh
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