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Multimodal LLMs (MLLMs) are capable of performing complex data analysis, visual question answering, generation, and reasoning tasks. However, their ability to analyze biometric data is relatively underexplored. In this work, we investigate…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Ekta Gavas , Sudipta Banerjee , Chinmay Hegde , Nasir Memon

Virtual cell (VC) models aim to predict cellular responses to any perturbations in silico and have emerged as a promising approach for drug discovery and precision medicine. Yet, a clear gap still remains: while models routinely reported…

Cell Behavior · Quantitative Biology 2026-05-01 Xinjie Mao , Songming Zhang , Qianhong Wen , Xiangyu Wen , Kedu Jin , Hao Wu , Shuizhou Chen , Yuqiang Li , Lei Bai , Qi Liu , Ning Ding , Siqi Sun , Zhangyang Gao

With the integration of large language models (LLMs), embodied agents have strong capabilities to understand and plan complicated natural language instructions. However, a foreseeable issue is that those embodied agents can also flawlessly…

Cryptography and Security · Computer Science 2025-11-03 Sheng Yin , Xianghe Pang , Yuanzhuo Ding , Menglan Chen , Yutong Bi , Yichen Xiong , Wenhao Huang , Zhen Xiang , Jing Shao , Siheng Chen

Recent advances in large language models have enabled LLM-based agents to achieve strong performance on a variety of benchmarks. However, their performance in real-world deployments often that observed on benchmark settings, especially in…

Artificial Intelligence · Computer Science 2026-02-19 Ruipeng Wang , Yuxin Chen , Yukai Wang , Chang Wu , Junfeng Fang , Xiaodong Cai , Qi Gu , Hui Su , An Zhang , Xiang Wang , Xunliang Cai , Tat-Seng Chua

With the rapid development of LLM-based agents, there is a growing trend to incorporate agent-specific data into the pre-training stage of LLMs, aiming to better align LLMs with real-world autonomous task execution. However, current…

Artificial Intelligence · Computer Science 2025-10-29 Jiarui Qin , Yunjia Xi , Junjie Huang , Renting Rui , Di Yin , Weiwen Liu , Yong Yu , Weinan Zhang , Xing Sun

Large Multimodal Models (LMMs) have ushered in a new era in artificial intelligence, merging capabilities in both language and vision to form highly capable Visual Foundation Agents. These agents are postulated to excel across a myriad of…

Computational phenotyping is a central informatics activity with resulting cohorts supporting a wide variety of applications. However, it is time-intensive because of manual data review and limited automation. Since LLMs have demonstrated…

Quantitative Methods · Quantitative Biology 2025-08-18 Sarah Pungitore , Shashank Yadav , Molly Douglas , Jarrod Mosier , Vignesh Subbian

LLM agents are increasingly deployed as executable systems that use tools, modify workspaces, and produce concrete artifacts. In such workflows, performance depends not only on the base model, but also on the harness: the system layer that…

Artificial Intelligence · Computer Science 2026-05-28 Yilun Yao , Xinyu Tan , Chao-Hsuan Liu , Yaoming Li , Zhengyang Wang , Wenhan Yu , Zhewen Tan , Yuxuan Tian , Guangxiang Zhao , Lin Sun , Xiangzheng Zhang , Tong Yang

Evaluating Large Language Models (LLMs) on repository-level feature implementation is a critical frontier in software engineering. However, establishing a benchmark that faithfully mirrors realistic development scenarios remains a…

Computation and Language · Computer Science 2026-02-19 Haorui Chen , Chengze Li , Jia Li

Generative AI agents, software systems powered by Large Language Models (LLMs), are emerging as a promising approach to automate cybersecurity tasks. Among the others, penetration testing is a challenging field due to the task complexity…

Cryptography and Security · Computer Science 2024-10-29 Luca Gioacchini , Marco Mellia , Idilio Drago , Alexander Delsanto , Giuseppe Siracusano , Roberto Bifulco

Proactive agents that anticipate user intentions without explicit prompts represent a significant evolution in human-AI interaction, promising to reduce cognitive load and streamline workflows. However, existing datasets suffer from two…

Human-Computer Interaction · Computer Science 2026-02-11 Yuanbo Tang , Huaze Tang , Tingyu Cao , Lam Nguyen , Anping Zhang , Xinwen Cao , Chunkang Liu , Wenbo Ding , Yang Li

With collective endeavors, multimodal large language models (MLLMs) are undergoing a flourishing development. However, their performances on image aesthetics perception remain indeterminate, which is highly desired in real-world…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Yipo Huang , Quan Yuan , Xiangfei Sheng , Zhichao Yang , Haoning Wu , Pengfei Chen , Yuzhe Yang , Leida Li , Weisi Lin

Large Language Models (LLMs) based autonomous agents demonstrate multifaceted capabilities to contribute substantially to economic production. However, existing benchmarks remain focused on single agentic capability, failing to capture…

Artificial Intelligence · Computer Science 2026-04-24 Keyu Li , Junhao Shi , Yang Xiao , Mohan Jiang , Jie Sun , Yunze Wu , Dayuan Fu , Shijie Xia , Xiaojie Cai , Tianze Xu , Weiye Si , Wenjie Li , Dequan Wang , Pengfei Liu

Large language models are now integrated into many scientific workflows, accelerating data analysis, hypothesis generation, and design space exploration. In parallel with this growth, there is a growing need to carefully evaluate whether…

Autonomous agents powered by large language models (LLMs) are increasingly deployed in real-world applications requiring complex, long-horizon workflows. However, existing benchmarks predominantly focus on atomic tasks that are…

Computation and Language · Computer Science 2025-08-13 Weixuan Wang , Dongge Han , Daniel Madrigal Diaz , Jin Xu , Victor Rühle , Saravan Rajmohan

Large Language Model (LLM) agents have shown great potential for solving real-world problems and promise to be a solution for tasks automation in industry. However, more benchmarks are needed to systematically evaluate automation agents…

Artificial Intelligence · Computer Science 2025-07-16 Yinsheng Li , Zhen Dong , Yi Shao

The emergence of Large Language Models (LLMs) has catalyzed a paradigm shift in programming, giving rise to "vibe coding", where users can build complete projects and even control computers using natural language instructions. This paradigm…

Software Engineering · Computer Science 2026-03-27 Fanheng Kong , Jingyuan Zhang , Yang Yue , Chenxi Sun , Yang Tian , Shi Feng , Xiaocui Yang , Daling Wang , Yu Tian , Jun Du , Wenchong Zeng , Han Li , Kun Gai

Video production workflows offer a rich and demanding arena for evaluating multimodal AI agents: they require composite capabilities across text, image, audio, and video understanding, along with long-horizon planning, and tool use. To this…

Cryptography and Security · Computer Science 2026-05-28 Zongheng Cao , Yi Zheng , Rui Song , Xinyu Hu

In contrast to their remarkable performance on general knowledge QA, the true abilities of Large Language Models (LLMs) in tasks demanding deep, specialized reasoning, such as in protein biology, have yet to be thoroughly investigated.…

Quantitative Methods · Quantitative Biology 2025-12-30 Dingyi Rong , Zijian Chen , Qi Jia , Kaiwei Zhang , Haotian Lu , Guangtao Zhai , Ning Liu

AI agents could accelerate scientific discovery by automating hypothesis formation, experiment design, coding, execution, and analysis, yet existing benchmarks probe narrow skills in simplified settings. To address this gap, we introduce…