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Whole slide imaging (WSI) has transformed digital pathology by enabling computational analysis of gigapixel histopathology images. Recent foundation model advances have accelerated progress in computational pathology, facilitating joint…

Computer Vision and Pattern Recognition · Computer Science 2026-03-20 Peihang Wu , Zehong Chen , Lijian Xu

Hit identification is a central challenge in early drug discovery, traditionally requiring substantial experimental resources. Recent advances in artificial intelligence, particularly large language models (LLMs), have enabled virtual…

Although machine learning (ML) models of AI achieve high performances in medicine, they are not free of errors. Empowering clinicians to identify incorrect model recommendations is crucial for engendering trust in medical AI. Explainable AI…

Artificial Intelligence · Computer Science 2022-12-20 Isil Guzey , Ozlem Ucar , Nukhet Aladag Ciftdemir , Betul Acunas

Existing autonomous robot navigation systems allow robots to move from one point to another in a collision-free manner. However, when facing new environments, these systems generally require re-tuning by expert roboticists with a good…

Robotics · Computer Science 2020-07-17 Xuesu Xiao , Bo Liu , Garrett Warnell , Jonathan Fink , Peter Stone

Recent advances in deep learning are driven by the growing scale of computation, data, and models. However, efficiently training large-scale models on distributed systems requires an intricate combination of data, operator, and pipeline…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-08-22 Jinfan Chen , Shigang Li , Ran Gun , Jinhui Yuan , Torsten Hoefler

The design of alloys is a multi-scale problem that requires a holistic approach that involves retrieving relevant knowledge, applying advanced computational methods, conducting experimental validations, and analyzing the results, a process…

Artificial Intelligence · Computer Science 2024-07-16 Alireza Ghafarollahi , Markus J. Buehler

Whole-slide image analysis via the means of computational pathology often relies on processing tessellated gigapixel images with only slide-level labels available. Applying multiple instance learning-based methods or transformer models is…

Computer Vision and Pattern Recognition · Computer Science 2023-10-20 Joshua Butke , Noriaki Hashimoto , Ichiro Takeuchi , Hiroaki Miyoshi , Koichi Ohshima , Jun Sakuma

Compared to current AI or robotic systems, humans navigate their environment with ease, making tasks such as data collection trivial. However, humans find it harder to model complex relationships hidden in the data. AI systems, especially…

Artificial Intelligence · Computer Science 2022-06-17 Ryan Nguyen , Rahul Rai

Agent-based modeling plays an essential role in gaining insights into biology, sociology, economics, and other fields. However, many existing agent-based simulation platforms are not suitable for large-scale studies due to the low…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-04-25 Lukas Breitwieser , Ahmad Hesam , Fons Rademakers , Juan Gómez Luna , Onur Mutlu

Agent skills provide a lightweight way to adapt LLM agents to specialized domains by storing reusable procedural knowledge in structured files. However, whether downloaded from third parties or self-generated, these skills are often…

Artificial Intelligence · Computer Science 2026-05-28 Hanyu Wang , Yifan Lan , Bochuan Cao , Lu Lin , Jinghui Chen

Automated Machine Learning (AutoML) is a rapidly growing set of technologies that automate the model development pipeline by searching model space and generating candidate models. A critical, final step of AutoML is human selection of a…

Human-Computer Interaction · Computer Science 2021-04-12 Shweta Narkar , Yunfeng Zhang , Q. Vera Liao , Dakuo Wang , Justin D Weisz

Cellular image segmentation is essential for quantitative biology yet remains difficult due to heterogeneous modalities, morphological variability, and limited annotations. We present GenCellAgent, a training-free multi-agent framework that…

Quantitative Methods · Quantitative Biology 2026-05-12 Xi Yu , Yang Yang , Qun Liu , Yonghua Du , Sean McSweeney , Yuewei Lin

Inevitable domain and task discrepancies in real-world scenarios can impair the generalization performance of the pre-trained deep models for medical data. Therefore, we audaciously propose that we should build a general-purpose medical AI…

Computer Vision and Pattern Recognition · Computer Science 2023-03-14 Huahui Yi , Ziyuan Qin , Qicheng Lao , Wei Xu , Zekun Jiang , Dequan Wang , Shaoting Zhang , Kang Li

In pathology image analysis, obtaining and maintaining high-quality annotated samples is an extremely labor-intensive task. To overcome this challenge, mixing-based methods have emerged as effective alternatives to traditional preprocessing…

Computer Vision and Pattern Recognition · Computer Science 2023-07-25 Tianyi Zhang , Zhiling Yan , Chunhui Li , Nan Ying , Yanli Lei , Yunlu Feng , Yu Zhao , Guanglei Zhang

The progress in Computer Aided Diagnosis (CADx) of Wireless Capsule Endoscopy (WCE) is thwarted by the lack of data. The inadequacy in richly representative healthy and abnormal conditions results in isolated analyses of pathologies, that…

Computer Vision and Pattern Recognition · Computer Science 2021-07-01 Anuja Vats , Marius Pedersen , Ahmed Mohammed , Øistein Hovde

Large language models (LLMs) have had a significant impact on diverse research domains, including medicine and healthcare. However, the potential of LLMs as copilots in medical education remains underexplored. Current AI-assisted…

Artificial Intelligence · Computer Science 2024-08-27 Hao Wei , Jianing Qiu , Haibao Yu , Wu Yuan

Recent pathological foundation models have substantially advanced visual representation learning and multimodal interaction. However, most models still rely on a static inference paradigm in which whole-slide images are processed once to…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Shengyi Hua , Jianfeng Wu , Tianle Shen , Kangzhe Hu , Zhongzhen Huang , Shujuan Ni , Zhihong Zhang , Yuan Li , Zhe Wang , Xiaofan Zhang

In digital pathology, whole-slide images (WSIs) are often difficult to handle due to their gigapixel scale, so most approaches train patch encoders via self-supervised learning (SSL) and then aggregate the patch-level embeddings via…

Computer Vision and Pattern Recognition · Computer Science 2025-08-15 Myeongjang Pyeon , Janghyeon Lee , Minsoo Lee , Juseung Yun , Hwanil Choi , Jonghyun Kim , Jiwon Kim , Yi Hu , Jongseong Jang , Soonyoung Lee

Pre-trained encoders for offline feature extraction followed by multiple instance learning (MIL) aggregators have become the dominant paradigm in computational pathology (CPath), benefiting cancer diagnosis and prognosis. However,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-24 Wenhao Tang , Rong Qin , Heng Fang , Fengtao Zhou , Hao Chen , Xiang Li , Ming-Ming Cheng

The automation of chemical research through self-driving laboratories (SDLs) promises to accelerate scientific discovery, yet the reliability and granular performance of the underlying AI agents remain critical, under-examined challenges.…

Artificial Intelligence · Computer Science 2025-10-01 Gihan Panapitiya , Emily Saldanha , Heather Job , Olivia Hess