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Background: Globally we face a projected shortage of 11 million healthcare practitioners by 2030, and administrative burden consumes 50% of clinical time. Artificial intelligence (AI) has the potential to help alleviate these problems.…

Human-Computer Interaction · Computer Science 2025-08-01 Hashim Hayat , Maksim Kudrautsau , Evgeniy Makarov , Vlad Melnichenko , Tim Tsykunou , Piotr Varaksin , Matt Pavelle , Adam Z. Oskowitz

Multiple Instance Learning (MIL) methods allow for gigapixel Whole-Slide Image (WSI) analysis with only slide-level annotations. Interpretability is crucial for safely deploying such algorithms in high-stakes medical domains. Traditional…

Computer Vision and Pattern Recognition · Computer Science 2025-01-07 Susu Sun , Leslie Tessier , Frédérique Meeuwsen , Clément Grisi , Dominique van Midden , Geert Litjens , Christian F. Baumgartner

Vision language models (VLMs) are increasingly deployed as controllers with access to external tools for complex reasoning and decision-making, yet their effectiveness remains limited by the scarcity of high-quality multimodal trajectories…

Computer Vision and Pattern Recognition · Computer Science 2025-10-22 Tajamul Ashraf , Umair Nawaz , Abdelrahman M. Shaker , Rao Anwer , Philip Torr , Fahad Shahbaz Khan , Salman Khan

We present Agent Lightning, a flexible and extensible framework that enables Reinforcement Learning (RL)-based training of Large Language Models (LLMs) for any AI agent. Unlike existing methods that tightly couple RL training with agent or…

Artificial Intelligence · Computer Science 2025-08-06 Xufang Luo , Yuge Zhang , Zhiyuan He , Zilong Wang , Siyun Zhao , Dongsheng Li , Luna K. Qiu , Yuqing Yang

Digital whole slides images contain an enormous amount of information providing a strong motivation for the development of automated image analysis tools. Particularly deep neural networks show high potential with respect to various tasks…

Computer Vision and Pattern Recognition · Computer Science 2023-12-07 Michael Gadermayr , Maximilian Tschuchnig

Pathologists are facing an increasing workload due to a growing volume of cases and the need for more comprehensive diagnoses. Aiming to facilitate workload reduction and faster turnaround times, we developed an artificial intelligence (AI)…

Computer Vision and Pattern Recognition · Computer Science 2024-10-15 Ruben T. Lucassen , Nikolas Stathonikos , Gerben E. Breimer , Mitko Veta , Willeke A. M. Blokx

Developing artificial intelligence (AI) and machine learning (ML) models for medical imaging typically involves extensive training and testing on large datasets, consuming significant computational time, energy, and resources. There is a…

Image and Video Processing · Electrical Eng. & Systems 2024-12-13 Raj Hansini Khoiwal , Alan B. McMillan

In pre-clinical pathology, there is a paradox between the abundance of raw data (whole slide images from many organs of many individual animals) and the lack of pixel-level slide annotations done by pathologists. Due to time constraints and…

Computer Vision and Pattern Recognition · Computer Science 2023-02-06 Marco Bertolini , Van-Khoa Le , Jake Pencharz , Andreas Poehlmann , Djork-Arné Clevert , Santiago Villalba , Floriane Montanari

There has been a rapidly growing interest in Automatic Symptom Detection (ASD) and Automatic Diagnosis (AD) systems in the machine learning research literature, aiming to assist doctors in telemedicine services. These systems are designed…

Computation and Language · Computer Science 2022-10-14 Arsene Fansi Tchango , Rishab Goel , Zhi Wen , Julien Martel , Joumana Ghosn

Agent-based modeling is indispensable for studying complex systems across many domains. However, existing simulation platforms exhibit two major issues: performance and modularity. Low performance prevents simulations with a large number of…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-03-17 Lukas Johannes Breitwieser

AI agents execute complex multi-step processes, but current evaluation falls short: outcome metrics report success or failure without explaining why, and process-level approaches struggle to connect failure types to their precise locations…

Quality assurance is a critical but underexplored area in digital pathology, where even minor artifacts can have significant effects. Artifacts have been shown to negatively impact the performance of AI diagnostic models. In current…

Image and Video Processing · Electrical Eng. & Systems 2025-06-13 Meredith VandeHaar , M. Clinch , I. Yilmaz , M. A. Rahman , Y. Xiao , F. Dogany , H. M. Alazab , A. Nassar , Z. Akkus , B. Dangott

Foundation models for computational pathology are expected to facilitate the development of high-performing, generalisable deep learning systems. However, in addition to biologically relevant features, current foundation models also capture…

Artificial intelligence (AI) techniques are widely applied in the life sciences. However, applying innovative AI techniques to understand and deconvolute biological complexity is hindered by the learning curve for life science scientists to…

Artificial Intelligence · Computer Science 2024-03-28 Nisha Pillai , Athish Ram Das , Moses Ayoola , Ganga Gireesan , Bindu Nanduri , Mahalingam Ramkumar

Computational pathology holds substantial promise for improving diagnosis and guiding treatment decisions. Recent pathology foundation models enable the extraction of rich patch-level representations from large-scale whole-slide images…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Xiangde Luo , Jinxi Xiang , Yuanfeng Ji , Ruijiang Li

While recent advancements in Large Language Models have significantly advanced dermatological diagnosis, monolithic LLMs frequently struggle with fine-grained, large-scale multi-class diagnostic tasks and rare skin disease diagnosis owing…

Computer Vision and Pattern Recognition · Computer Science 2026-03-30 Zhangtianyi Chen , Yuhao Shen , Florensia Widjaja , Yan Xu , Liyuan Sun , Zijian Wang , Hongyi Chen , Wufei Dai , Juexiao Zhou

AI agents have become surprisingly proficient at software engineering over the past year, largely due to improvements in reasoning capabilities. This raises a deeper question: can these systems extend their capabilities to automate AI…

Software Engineering · Computer Science 2026-03-11 Ben Rank , Hardik Bhatnagar , Ameya Prabhu , Shira Eisenberg , Karina Nguyen , Matthias Bethge , Maksym Andriushchenko

As large language models (LLMs) become widespread in various application domains, a critical challenge the AI community is facing is how to train these large AI models in a cost-effective manner. Existing LLM training plans typically employ…

Machine Learning · Computer Science 2024-09-11 Jehyeon Bang , Yujeong Choi , Myeongwoo Kim , Yongdeok Kim , Minsoo Rhu

Machine learning (ML) models are increasingly being used in application domains that often involve working together with human experts. In this context, it can be advantageous to defer certain instances to a single human expert when they…

Artificial Intelligence · Computer Science 2022-06-17 Patrick Hemmer , Sebastian Schellhammer , Michael Vössing , Johannes Jakubik , Gerhard Satzger
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