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Atomic basis sets are widely employed within quantum mechanics based simulations of matter. We introduce a machine learning model that adapts the basis set to the local chemical environment of each atom, prior to the start of self…

Chemical Physics · Physics 2024-04-29 Danish Khan , Maximilian L. Ach , O. Anatole von Lilienfeld

The variational quantum eigensolver (VQE) is an algorithm for finding the ground states of a given Hamiltonian. Its application to binary-formulated combinatorial optimization (CO) has been widely studied in recent years. However, typical…

Quantum Physics · Physics 2025-08-08 Ningyi Xie , Xinwei Lee , Tiejin Chen , Yoshiyuki Saito , Nobuyoshi Asai , Dongsheng Cai

Molecule-optimized basis sets, based on approximate natural orbitals, are developed for accelerating the convergence of quantum calculations with strongly correlated (multi-referenced) electrons. We use a low-cost approximate solution of…

Chemical Physics · Physics 2014-02-12 Gergely Gidofalvi , David A. Mazziotti

This paper presents an easy-to-implement approach to mitigate the challenges posed by barren plateaus (BPs) in randomly initialized parameterized quantum circuits (PQCs) within variational quantum algorithms (VQAs). Recent state-of-the-art…

Quantum Physics · Physics 2024-12-10 Muhammad Kashif , Muhammad Shafique

Quantum variational optimization has been posed as an alternative to solve optimization problems faster and at a larger scale than what classical methods allow. In this paper we study systematically the role of entanglement, the structure…

Quantum Physics · Physics 2021-12-30 Pablo Díez-Valle , Diego Porras , Juan José García-Ripoll

Large-scale eigenvalue problems pose a significant challenge to classical computers. While there are efficient quantum algorithms for unitary or Hermitian matrices, eigenvalue problems for non-normal matrices remain open in quantum…

Quantum Physics · Physics 2026-03-25 Honghong Lin , Yun Shang

The emerging field of quantum simulation of many-body systems is widely recognized as a very important application of quantum computing. A crucial step towards its realization in the context of many-electron systems requires a rigorous…

Atomic Physics · Physics 2021-08-23 Sumeet , V. S. Prasannaa , B. P. Das , B. K. Sahoo

Variational quantum eigensolver ans\"atze hold considerable promise for ground-state energy calculations on near-term quantum hardware, yet most promising ansatz designs currently strongly depend on how well the molecular orbital basis…

Variational quantum algorithms (VQAs) are a modern family of quantum algorithms designed to solve optimization problems using a quantum computer. Typically VQAs rely on a feedback loop between the quantum device and a classical optimization…

Quantum Physics · Physics 2022-08-26 Alexey Uvarov

Variational quantum algorithms provide a direct, physics-based approach to protein structure prediction, but their accuracy is limited by the coarse resolution of the energy landscapes generated on current noisy devices. We propose a hybrid…

Emerging Technologies · Computer Science 2025-10-09 Yuqi Zhang , Yuxin Yang , Feixiong Chen , Cheng-Chang Lu , Nima Saeidi , Samuel L. Volchenboum , Junhan Zhao , Siwei Chen , Weiwen Jiang , Qiang Guan

We present a basis-set-free approach to the variational quantum eigensolver using an adaptive representation of the spatial part of molecular wavefunctions. Our approach directly determines system-specific representations of qubit…

Quantum Physics · Physics 2021-01-05 Jakob S. Kottmann , Philipp Schleich , Teresa Tamayo-Mendoza , Alán Aspuru-Guzik

The paper proposes a method to obtain the optimal basis set for solving the self consistent field (SCF) equations for large atomic systems in order to calculate the energy barriers in tunneling structures, with higher accuracy and speed.…

Mathematical Physics · Physics 2009-12-16 Sever Spanulescu

The potential energy surface (PES) of molecules with respect to their nuclear positions is a primary tool in understanding chemical reactions from first principles. However, obtaining this information is complicated by the fact that…

This work presents a detailed empirical analysis of Bayesian optimisation with information sharing (BOIS) for the variational quantum eigensolver (VQE). The method is applied to computing the potential energy surfaces (PES) of the hydrogen…

Quantum Physics · Physics 2024-05-24 Milena Röhrs , Alexey Bochkarev , Arcesio C. Medina

Quantum systems have historically been formidable to simulate using classical computational methods, particularly as the system size grows. In recent years, advancements in quantum computing technology have offered new opportunities for…

Quantum Physics · Physics 2023-09-06 Jinao Wang , Rimika Jaiswal

We describe a semidefinite relaxation method which finds lower bounds to the ground state energy of a quantum Hamiltonian subject to Hermitian linear constraints along with approximations of ground state expectation values. We show that…

Strongly Correlated Electrons · Physics 2026-05-29 Michael G. Scheer

Hamiltonian simulation is a domain where quantum computers have the potential to outperform their classical counterparts. One of the main challenges of such quantum algorithms is increasing the system size, which is necessary to achieve…

Quantum Physics · Physics 2025-02-07 Erenay Karacan , Yanbin Chen , Christian B. Mendl

Quantum machine learning algorithms have emerged to be a promising alternative to their classical counterparts as they leverage the power of quantum computers. Such algorithms have been developed to solve problems like electronic structure…

Chemical Physics · Physics 2021-10-29 Manas Sajjan , Shree Hari Sureshbabu , Sabre Kais

We demonstrate the importance of symmetries in Variational Quantum Eigensolver (VQE) algorithms to prepare the ground or specific low-lying states of quantum Hamiltonians. We examine two spin problems, one with random all-to-all couplings…

Quantum Physics · Physics 2025-10-09 Ivana Miháliková , Joseph Carlson , Duff Neill , Ionel Stetcu

Parameterized quantum circuits (PQCs) have emerged as a foundational element in the development and applications of quantum algorithms. However, when initialized with random parameter values, PQCs often exhibit barren plateaus (BP). These…

Quantum Physics · Physics 2025-07-02 Muhammad Kashif , Muhammad Rashid , Saif Al-Kuwari , Muhammad Shafique