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When assessing the presence of an exposure causal effect on a given outcome, it is well known that classical measurement error of the exposure can reduce the power of a test of the null hypothesis in question, although its type I error rate…

Methodology · Statistics 2016-10-18 Caleb H. Miles , Joel Schwartz , Eric J. Tchetgen Tchetgen

Network interference amounts to the treatment status of one unit affecting the potential outcome of other units in the population. Testing for spillover effects in this setting makes the null hypothesis non-sharp. An interesting approach to…

Methodology · Statistics 2025-09-24 Supriya Tiwari , Pallavi Basu

Linear mixed-effects models have increasingly replaced mixed-model analyses of variance for statistical inference in factorial psycholinguistic experiments. Although LMMs have many advantages over ANOVA, like ANOVAs, setting them up for…

Applications · Statistics 2017-02-14 Hannes Matuschek , Reinhold Kliegl , Shravan Vasishth , Harald Baayen , Douglas Bates

Randomized experiments on a network often involve interference between connected units; i.e., a situation in which an individual's treatment can affect the response of another individual. Current approaches to deal with interference, in…

Methodology · Statistics 2017-05-17 Guillaume Basse , Edoardo Airoldi

The lack of specifications is a key difference between traditional software engineering and machine learning. We discuss how it drastically impacts how we think about divide-and-conquer approaches to system design, and how it impacts reuse,…

Software Engineering · Computer Science 2021-05-14 Christian Kästner , Eunsuk Kang , Sven Apel

Permutation testing in linear models, where the number of nuisance coefficients is smaller than the sample size, is a well-studied topic. The common approach of such tests is to permute residuals after regressing on the nuisance covariates.…

Methodology · Statistics 2020-10-09 Jesse Hemerik , Magne Thoresen , Livio Finos

Understanding statistical inference under possibly non-sparse high-dimensional models has gained much interest recently. For a given component of the regression coefficient, we show that the difficulty of the problem depends on the sparsity…

Statistics Theory · Mathematics 2022-08-22 Jelena Bradic , Jianqing Fan , Yinchu Zhu

A central problem in Binary Hypothesis Testing (BHT) is to determine the optimal tradeoff between the Type I error (referred to as false alarm) and Type II (referred to as miss) error. In this context, the exponential rate of convergence of…

Information Theory · Computer Science 2021-11-29 Sebastian Espinosa , Jorge F. Silva , Pablo Piantanida

FDA's Project Optimus initiative for oncology drug development emphasizes selecting a dose that optimizes both efficacy and safety. When an inferentially adaptive Phase 2/3 design with dose selection is implemented to comply with the…

Applications · Statistics 2024-12-12 Cong Chen , Mo Huang , Xuekui Zhang

Estimating the effects of interventions in networks is complicated when the units are interacting, such that the outcomes for one unit may depend on the treatment assignment and behavior of many or all other units (i.e., there is…

Methodology · Statistics 2014-08-15 Dean Eckles , Brian Karrer , Johan Ugander

In large scale genetic association studies, a primary aim is to test for association between genetic variants and a disease outcome. The variants of interest are often rare, and appear with low frequency among subjects. In this situation,…

Methodology · Statistics 2017-12-20 Arjun Sondhi , Kenneth Martin Rice

Objective: This paper proposes a framework to support the scientific research of standards so that they can be better measured, evaluated, and designed. Methods: Beginning with the notion of common models, the framework describes the…

Other Computer Science · Computer Science 2023-08-17 Enrico Coiera

In high-dimensional linear models, the sparsity assumption is typically made, stating that most of the parameters are equal to zero. Under the sparsity assumption, estimation and, recently, inference have been well studied. However, in…

Methodology · Statistics 2019-07-09 Yinchu Zhu , Jelena Bradic

In this paper, we propose new specification tests for regression models with measurement errors in the explanatory variables. Inspired by the integrated conditional moment (ICM) approach, we use a deconvoluted residual-marked empirical…

Econometrics · Economics 2025-11-07 Xiaojun Song , Jichao Yuan

This paper proposes new nonparametric diagnostic tools to assess the asymptotic validity of different treatment effects estimators that rely on the correct specification of the propensity score. We derive a particular restriction relating…

Methodology · Statistics 2019-02-11 Pedro H. C. Sant'Anna , Xiaojun Song

The inflation of Type I error rates is thought to be one of the causes of the replication crisis. Questionable research practices such as p-hacking are thought to inflate Type I error rates above their nominal level, leading to unexpectedly…

Methodology · Statistics 2024-12-31 Mark Rubin

Statistical evaluation aims to estimate the generalization performance of a model using held-out i.i.d.\ test data sampled from the ground-truth distribution. In supervised learning settings such as classification, performance metrics such…

Machine Learning · Computer Science 2026-04-08 Shashaank Aiyer , Yishay Mansour , Shay Moran , Han Shao

It is common to conduct causal inference in matched observational studies by proceeding as though treatment assignments within matched sets are assigned uniformly at random and using this distribution as the basis for inference. This…

Methodology · Statistics 2023-11-14 Samuel D. Pimentel , Yaxuan Huang

We revisit the fundamental question of simple-versus-simple hypothesis testing with an eye towards computational complexity, as the statistically optimal likelihood ratio test is often computationally intractable in high-dimensional…

Statistics Theory · Mathematics 2025-05-05 Ankur Moitra , Alexander S. Wein

Selective classification is a powerful tool for automated decision-making in high-risk scenarios, allowing classifiers to act only when confident and abstain when uncertainty is high. Given a target accuracy, our goal is to minimize…

Statistics Theory · Mathematics 2025-10-28 Mohamed Ndaoud , Peter Radchenko , Bradley Rava