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Gene expression analysis holds the key to many biomedical discoveries, yet extracting insights from raw transcriptomic data remains formidable due to the complexity of multiple large, semi-structured files and the need for extensive domain…

Artificial Intelligence · Computer Science 2026-05-19 Haoyang Liu , Yijiang Li , Haohan Wang

Large Language Model (LLM) based multi-agent systems (MAS) show remarkable potential in collaborative problem-solving, yet they still face critical challenges: low communication efficiency, poor scalability, and a lack of effective…

Computation and Language · Computer Science 2025-02-19 Weize Chen , Jiarui Yuan , Chen Qian , Cheng Yang , Zhiyuan Liu , Maosong Sun

Large Language Models (LLMs) have shown remarkable performance in completing various tasks. However, solving complex problems often requires the coordination of multiple agents, raising a fundamental question: how to effectively select and…

Computation and Language · Computer Science 2026-04-02 Eric Hanchen Jiang , Levina Li , Rui Sun , Xiao Liang , Yubei Li , Yuchen Wu , Haozheng Luo , Hengli Li , Zhi Zhang , Zhaolu Kang , Kai-Wei Chang , Ying Nian Wu

Scaling vision-language models into Visual Multiagent Systems (VMAS) is hindered by two coupled issues. First, communication topologies are fixed before inference, leaving them blind to visual content and query context; second, agent…

Artificial Intelligence · Computer Science 2026-04-21 Zheng Nie , Ruolin Shen , Xinlei Yu , Bo Yin , Jiangning Zhang , Xiaobin Hu

While multi-agent systems (MAS) have demonstrated superior performance over single-agent approaches in complex reasoning tasks, they often suffer from significant computational inefficiencies. Existing frameworks typically deploy large…

Artificial Intelligence · Computer Science 2026-01-27 Jingbo Wang , Sendong Zhao , Jiatong Liu , Haochun Wang , Wanting Li , Bing Qin , Ting Liu

Multi-agent systems (MAS) are increasingly used for open-ended idea generation, driven by the expectation that collective interaction will broaden the exploration diversity. However, when and why such collaboration truly expands the…

Multiagent Systems · Computer Science 2026-04-22 Nuo Chen , Yicheng Tong , Yuzhe Yang , Yufei He , Xueyi Zhang , Qingyun Zou , Qian Wang , Bingsheng He

Test-time scaling (TTS) enhances the performance of large language models (LLMs) by allocating additional compute resources during inference. However, existing research primarily investigates TTS in single-stage tasks; while many real-world…

Artificial Intelligence · Computer Science 2025-10-23 Fali Wang , Hui Liu , Zhenwei Dai , Jingying Zeng , Zhiwei Zhang , Zongyu Wu , Chen Luo , Zhen Li , Xianfeng Tang , Qi He , Suhang Wang

Effectively processing long contexts remains a fundamental yet unsolved challenge for large language models (LLMs). Existing single-LLM-based methods primarily reduce the context window or optimize the attention mechanism, but they often…

Computation and Language · Computer Science 2026-04-22 Yichen Jiang , Jiakang Yuan , Chongjun Tu , Peng Ye , Tao Chen

Several Multi-Agent System (MAS) metamodels and languages have been proposed in the literature to support the development of agent-based applications. MAS metamodels are used to capture a collection of concepts the relevant entities and…

Multiagent Systems · Computer Science 2021-11-29 Marx Viana , Paulo Alencar , Carlos Lucena

Multi-agent systems (MAS) increasingly solve complex tasks by orchestrating agents and tools selected from rapidly growing marketplaces. As these marketplaces expand, many candidates become functionally overlapping, making selection not…

Multiagent Systems · Computer Science 2026-02-02 Xinyuan Song , Liang Zhao

In autonomic computing, self-adaptation has been proposed as a fundamental paradigm to manage the complexity of multiagent systems (MASs). This achieved by extending a system with support to monitor and adapt itself to achieve specific…

Multiagent Systems · Computer Science 2023-07-13 Nathalia Nascimento , Paulo Alencar , Donald Cowan

Recently, the field of Multi-Agent Systems (MAS) has gained popularity as researchers are trying to develop artificial intelligence capable of efficient collective reasoning. Agents based on Large Language Models (LLMs) perform well in…

Multiagent Systems · Computer Science 2025-07-30 Adam Kostka , Jarosław A. Chudziak

Large language models (LLMs) have demonstrated exceptional potential in complex reasoning,pioneering a new paradigm for autonomous agent decision making in dynamic settings. However, in Real-Time Strategy (RTS) scenarios, LLMs suffer from a…

Multiagent Systems · Computer Science 2026-03-26 Li Ma , Hao Peng , Yiming Wang , Hongbin Luo , Jie Liu , Kongjing Gu , Guanlin Wu , Hui Lin , Lei Ren

Multi-Agent Systems (MAS) built on Large Language Models (LLMs) often exhibit high variance in their reasoning trajectories. Process verification, which evaluates intermediate steps in trajectories, has shown promise in general reasoning…

Artificial Intelligence · Computer Science 2026-02-04 Vishal Venkataramani , Haizhou Shi , Zixuan Ke , Austin Xu , Xiaoxiao He , Yingbo Zhou , Semih Yavuz , Hao Wang , Shafiq Joty

Large language model (LLM)-driven multi-agent systems (MAS) are transforming how humans and AIs collaboratively generate ideas and artifacts. While existing surveys provide comprehensive overviews of MAS infrastructures, they largely…

Human-Computer Interaction · Computer Science 2025-05-28 Yi-Cheng Lin , Kang-Chieh Chen , Zhe-Yan Li , Tzu-Heng Wu , Tzu-Hsuan Wu , Kuan-Yu Chen , Hung-yi Lee , Yun-Nung Chen

Recent advancements in Large Language Models (LLMs) have substantially evolved Multi-Agent Systems (MASs) capabilities, enabling systems that not only automate tasks but also leverage near-human reasoning capabilities. To achieve this,…

Artificial Intelligence · Computer Science 2025-02-27 Humza Sami , Mubashir ul Islam , Samy Charas , Asav Gandhi , Pierre-Emmanuel Gaillardon , Valerio Tenace

Large Reasoning Models (LRMs) face two fundamental limitations: excessive token consumption when overanalyzing simple information processing tasks, and inability to access up-to-date knowledge beyond their training data. We introduce MARS…

Artificial Intelligence · Computer Science 2026-02-03 Guoxin Chen , Zile Qiao , Wenqing Wang , Donglei Yu , Xuanzhong Chen , Hao Sun , Minpeng Liao , Kai Fan , Yong Jiang , Penguin Xie , Wayne Xin Zhao , Ruihua Song , Fei Huang

The emergence of Large Language Models (LLMs) is rapidly accelerating the development of autonomous multi-agent systems (MAS), paving the way for the Internet of Agents. However, traditional centralized MAS architectures present significant…

Multiagent Systems · Computer Science 2025-12-03 Yepeng Ding , Ahmed Twabi , Junwei Yu , Lingfeng Zhang , Tohru Kondo , Hiroyuki Sato

Multi-agent systems (MAS) built on multimodal large language models exhibit strong collaboration and performance. However, their growing openness and interaction complexity pose serious risks, notably jailbreak and adversarial attacks.…

Artificial Intelligence · Computer Science 2025-09-09 Zhenyu Pan , Yiting Zhang , Yutong Zhang , Jianshu Zhang , Haozheng Luo , Yuwei Han , Dennis Wu , Hong-Yu Chen , Philip S. Yu , Manling Li , Han Liu

Multi-agent systems (MAS) built on large language models promise improved problem-solving through collaboration, yet they often fail to consistently outperform strong single-agent baselines due to error propagation at inter-agent message…

Artificial Intelligence · Computer Science 2026-01-21 Bohan Lin , Kuo Yang , Zelin Tan , Yingchuan Lai , Chen Zhang , Guibin Zhang , Xinlei Yu , Miao Yu , Xu Wang , Yudong Zhang , Yang Wang
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