Related papers: PPI2Text: Captioning Protein-Protein Interactions …
Protein sequences are abundant in repeating segments, both as exact copies and as approximate segments with mutations. These repeats are important for protein structure and function, motivating decades of algorithmic work on repeat…
We report a 3D structure-based method of predicting protein-protein interaction partners. It involves screening for pairs of tetrahedra representing interacting amino acids at the interface of the protein-protein complex, with one…
Remote sensing image captioning has advanced rapidly through encoder--decoder models, although the reliance on large annotated datasets and the focus on English restricts global applicability. To address these limitations, we propose the…
Text-rich images, where text serves as the central visual element guiding the overall understanding, are prevalent in real-world applications, such as presentation slides, scanned documents, and webpage snapshots. Tasks involving multiple…
APIs have intricate relations that can be described in text and represented as knowledge graphs to aid software engineering tasks. Existing relation extraction methods have limitations, such as limited API text corpus and affected by the…
Graph-structured information offers rich contextual information that can enhance language models by providing structured relationships and hierarchies, leading to more expressive embeddings for various applications such as retrieval,…
Protein Language Models (PLMs), pre-trained on extensive evolutionary data from natural proteins, have emerged as indispensable tools for protein design. While powerful, PLMs often struggle to produce proteins with precisely specified…
Drug-target interaction (DTI) prediction is of great significance for drug discovery and drug repurposing. With the accumulation of a large volume of valuable data, data-driven methods have been increasingly harnessed to predict DTIs,…
We present SPHINX, a versatile multi-modal large language model (MLLM) with a joint mixing of model weights, tuning tasks, and visual embeddings. First, for stronger vision-language alignment, we unfreeze the large language model (LLM)…
Large language models (LLMs) have shown great abilities of solving various natural language tasks in different domains. Due to the training objective of LLMs and their pre-training data, LLMs are not very well equipped for tasks involving…
Proteins are macromolecules which hardly act alone; they need to make interactions with some other proteins to do so. Numerous factors are there which can regulate the interactions between proteins [4]. Here in this present study we aim to…
Large language models (LLMs) have shown impressive capabilities in adapting to various tasks when provided with task-specific instructions. However, LLMs using standard decoding strategies often struggle with deviations from the inputs.…
Multimodal entity linking plays a crucial role in a wide range of applications. Recent advances in large language model-based methods have become the dominant paradigm for this task, effectively leveraging both textual and visual modalities…
Protein design has become a critical method in advancing significant potential for various applications such as drug development and enzyme engineering. However, protein design methods utilizing large language models with solely pretraining…
Brain-related research topics in artificial intelligence have recently gained popularity, particularly due to the expansion of what multimodal architectures can do from computer vision to natural language processing. Our main goal in this…
Large language models (LLMs) offer an inexpensive yet powerful way to annotate text, but are often inconsistent when compared with experts. These errors can bias downstream estimates of population parameters such as regression coefficients…
We participated, in the Article Classification and the Interaction Method subtasks (ACT and IMT, respectively) of the Protein-Protein Interaction task of the BioCreative III Challenge. For the ACT, we pursued an extensive testing of…
Cellular functions are based on the complex interplay of proteins, therefore the structure and dynamics of these protein-protein interaction (PPI) networks are the key to the functional understanding of cells. In the last years, large-scale…
The increasing volume of drug combinations in modern therapeutic regimens needs reliable methods for predicting drug-drug interactions (DDIs). While Large Language Models (LLMs) have revolutionized various domains, their potential in…
While accurate protein structure predictions are now available for nearly every observed protein sequence, predicted structures lack much of the functional context offered by experimental structure determination. We address this gap with…