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Deep image prior (DIP) has been successfully applied to positron emission tomography (PET) image restoration, enabling represent implicit prior using only convolutional neural network architecture without training dataset, whereas the…

Medical Physics · Physics 2024-04-23 Yuya Onishi , Fumio Hashimoto , Kibo Ote , Keisuke Matsubara , Masanobu Ibaraki

In dynamic positron emission tomography (PET) reconstruction, the importance of leveraging the temporal dependence of the data has been well appreciated. Current deep-learning solutions can be categorized in two groups in the way the…

Image and Video Processing · Electrical Eng. & Systems 2024-03-13 Yubo Ye , Huafeng Liu , Linwei Wang

Reconstruction of PET images is an ill-posed inverse problem and often requires iterative algorithms to achieve good image quality for reliable clinical use in practice, at huge computational costs. In this paper, we consider the PET…

Computer Vision and Pattern Recognition · Computer Science 2017-04-25 Jieqing Jiao , Sebastien Ourselin

One of the major challenges in design and developing of PET, scanners are the presence of inactive areas between the detector blocks which degrade the image spatial resolution and leads to streaking artifacts especially when we employ…

Medical Physics · Physics 2019-06-19 Isaac Shiri , Peyman Sheikhzadeh , Mohammad Reza Ay

Computational imaging is increasingly vital for a broad spectrum of applications, ranging from biological to material sciences. This includes applications where the object is known and sufficiently sparse, allowing it to be described with a…

Image and Video Processing · Electrical Eng. & Systems 2024-01-17 Jacob Seifert , Yifeng Shao , Allard P. Mosk

In practice, environments constantly change over time and space, posing significant challenges for object detectors trained based on a closed-set assumption, i.e., training and test data share the same distribution. To this end, continual…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Deng Li , Aming Wu , Yang Li , Yaowei Wang , Yahong Han

Low-dose Positron Emission Tomography (PET) reduces radiation exposure but suffers from severe noise and quantitative degradation. Diffusion-based denoising models achieve strong final reconstructions, yet their reverse trajectories are…

Positron emission tomography (PET) is a key nuclear medicine imaging modality that visualizes radiotracer distributions to quantify in vivo physiological and metabolic processes, playing an irreplaceable role in disease management. Despite…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Yichi Zhang , Le Xue , Wenbo Zhang , Lanlan Li , Feiyang Xiao , Yuchen Liu , Xiaohui Zhang , Hongwei Zhang , Shuqi Wang , Gang Feng , Liling Peng , Xin Gao , Yuanfan Xu , Yuan Qi , Kuangyu Shi , Hong Zhang , Yuan Cheng , Mei Tian , Zixin Hu

Positron Emission Tomography (PET) is a powerful medical imaging technique, but the design and evaluation of new PET scanner technologies present significant challenges. The process is typically divided into three major stages: 1. detector…

Instrumentation and Detectors · Physics 2026-01-30 J. Renner , J. J. Gómez-Cadenas , R. Soleti

Photomultiplier tubes (PMTs) are widely employed in particle and nuclear physics experiments. The accuracy of PMT waveform reconstruction directly impacts the detector's spatial and energy resolution. A key challenge arises when multiple…

High Energy Physics - Experiment · Physics 2026-02-06 Kainan Liu , Jingyu Huang , Guihong Huang , Jianyi Luo

Accurate attenuation and scatter corrections are crucial in positron emission tomography (PET) imaging for accurate visual interpretation and quantitative analysis. Traditional methods relying on computed tomography (CT) or magnetic…

Medical Physics · Physics 2025-11-14 Min Jeong Cho , Hyeong Seok Shim , Sungyu Kim , Jae Sung Lee

Generalizability of deep learning models may be severely affected by the difference in the distributions of the train (source domain) and the test (target domain) sets, e.g., when the sets are produced by different hardware. As a…

Image and Video Processing · Electrical Eng. & Systems 2022-08-02 Ivan Zakazov , Vladimir Shaposhnikov , Iaroslav Bespalov , Dmitry V. Dylov

Low-dose Positron Emission Tomography (PET) imaging presents a significant challenge due to increased noise and reduced image quality, which can compromise its diagnostic accuracy and clinical utility. Denoising diffusion probabilistic…

Image and Video Processing · Electrical Eng. & Systems 2025-03-03 Boxiao Yu , Savas Ozdemir , Jiong Wu , Yizhou Chen , Ruogu Fang , Kuangyu Shi , Kuang Gong

List-mode positron emission tomography (PET) image reconstruction is an important tool for PET scanners with many lines-of-response and additional information such as time-of-flight and depth-of-interaction. Deep learning is one possible…

Medical Physics · Physics 2024-02-13 Kibo Ote , Fumio Hashimoto , Yuya Onishi , Takashi Isobe , Yasuomi Ouchi

The generalization of deep learning-based low-dose computed tomography (CT) reconstruction models to doses unseen in the training data is important and remains challenging. Previous efforts heavily rely on paired data to improve the…

Image and Video Processing · Electrical Eng. & Systems 2025-06-30 Qi Gao , Zhihao Chen , Dong Zeng , Junping Zhang , Jianhua Ma , Hongming Shan

Positron emission tomography (PET) is a widely recognized technique for diagnosing neurodegenerative diseases, offering critical functional insights. However, its high costs and radiation exposure hinder its widespread use. In contrast,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-20 Yitong Li , Igor Yakushev , Dennis M. Hedderich , Christian Wachinger

Imaging modalities such as Computed Tomography (CT) and Positron Emission Tomography (PET) are key in cancer detection, inspiring Deep Neural Networks (DNN) models that merge these scans for tumor segmentation. When both CT and PET scans…

Image and Video Processing · Electrical Eng. & Systems 2024-04-23 Nada Saadi , Numan Saeed , Mohammad Yaqub , Karthik Nandakumar

PET imaging is widely employed for observing biological metabolic activities within the human body. However, numerous benign conditions can cause increased uptake of radiopharmaceuticals, confounding differentiation from malignant tumors.…

Image and Video Processing · Electrical Eng. & Systems 2024-10-31 Ran Hong , Yuxia Huang , Lei Liu , Zhonghui Wu , Bingxuan Li , Xuemei Wang , Qiegen Liu

Computed tomography (CT)-based attenuation and scatter correction improves quantitative PET but adds radiation exposure that is particularly undesirable in pediatric imaging. Existing CT-free methods are commonly trained in homogeneous…

Image and Video Processing · Electrical Eng. & Systems 2026-04-28 Jia-Mian Wu , Jun Liu , Siqi Li , Xiaoya Wang , Shibai Yin , Huanyu Luo , Lingling Zheng , Qiang Gao , Jigang Yang , Tai-Xiang Jiang

In positron emission tomography (PET), it is indispensable to perform attenuation correction in order to obtain the quantitatively accurate activity map (tracer distribution) in the body. Generally, this is carried out based on the…

Medical Physics · Physics 2025-10-16 Liyang Hu , Chong Chen
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