English
Related papers

Related papers: ProteinJEPA: Latent prediction complements protein…

200 papers

We introduce Brain-JEPA, a brain dynamics foundation model with the Joint-Embedding Predictive Architecture (JEPA). This pioneering model achieves state-of-the-art performance in demographic prediction, disease diagnosis/prognosis, and…

This paper demonstrates an approach for learning highly semantic image representations without relying on hand-crafted data-augmentations. We introduce the Image-based Joint-Embedding Predictive Architecture (I-JEPA), a non-generative…

Computer Vision and Pattern Recognition · Computer Science 2023-04-14 Mahmoud Assran , Quentin Duval , Ishan Misra , Piotr Bojanowski , Pascal Vincent , Michael Rabbat , Yann LeCun , Nicolas Ballas

Recent advances in self-supervised visual representation learning have demonstrated the effectiveness of predictive latent-space objectives for learning transferable features. In particular, Image-based Joint-Embedding Predictive…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Xiangteng He , Shunsuke Sakai , Shivam Chandhok , Sara Beery , Kun Yuan , Nicolas Padoy , Tatsuhito Hasegawa , Leonid Sigal

Masked language modeling (MLM), a self-supervised pretraining objective, is widely used in natural language processing for learning text representations. MLM trains a model to predict a random sample of input tokens that have been replaced…

Computation and Language · Computer Science 2021-09-07 Atsuki Yamaguchi , George Chrysostomou , Katerina Margatina , Nikolaos Aletras

Multivariate time series underpin modern critical infrastructure, making the prediction of anomalies a vital necessity for proactive risk mitigation. While Joint-Embedding Predictive Architectures (JEPA) offer a promising framework for…

Machine Learning · Computer Science 2026-02-05 Yanan He , Yunshi Wen , Xin Wang , Tengfei Ma

Protein-ligand binding affinity (PLBA) prediction is the fundamental task in drug discovery. Recently, various deep learning-based models predict binding affinity by incorporating the three-dimensional structure of protein-ligand complexes…

Biomolecules · Quantitative Biology 2023-12-21 Jiaxian Yan , Zhaofeng Ye , Ziyi Yang , Chengqiang Lu , Shengyu Zhang , Qi Liu , Jiezhong Qiu

Pretrained language models (PLMs) display impressive performances and have captured the attention of the NLP community. Establishing best practices in pretraining has, therefore, become a major focus of NLP research, especially since…

Computation and Language · Computer Science 2024-10-08 Zihao Li , Shaoxiong Ji , Timothee Mickus , Vincent Segonne , Jörg Tiedemann

Unsupervised multitask pre-training has been the critical method behind the recent success of language models (LMs). However, supervised multitask learning still holds significant promise, as scaling it in the post-training stage trends…

Computation and Language · Computer Science 2024-12-02 Daixuan Cheng , Yuxian Gu , Shaohan Huang , Junyu Bi , Minlie Huang , Furu Wei

Pre-trained LLMs have demonstrated substantial capabilities across a range of conventional natural language processing (NLP) tasks, such as summarization and entity recognition. In this paper, we explore the application of LLMs in the…

Quantitative Methods · Quantitative Biology 2024-08-14 Kamyar Zeinalipour , Neda Jamshidi , Monica Bianchini , Marco Maggini , Marco Gori

We propose ProtLLM, a versatile cross-modal large language model (LLM) for both protein-centric and protein-language tasks. ProtLLM features a unique dynamic protein mounting mechanism, enabling it to handle complex inputs where the natural…

Biomolecules · Quantitative Biology 2024-03-14 Le Zhuo , Zewen Chi , Minghao Xu , Heyan Huang , Heqi Zheng , Conghui He , Xian-Ling Mao , Wentao Zhang

Recent advances in Protein Language Models (PLMs) have transformed protein engineering, yet unlike their counterparts in Natural Language Processing (NLP), current PLMs exhibit a fundamental limitation: they excel in either Protein Language…

Computational Engineering, Finance, and Science · Computer Science 2025-09-16 Liuzhenghao Lv , Zongying Lin , Hao Li , Yuyang Liu , Jiaxi Cui , Calvin Yu-Chian Chen , Li Yuan , Yonghong Tian

Masked language modeling (MLM) is a widely used self-supervised pretraining objective, where a model needs to predict an original token that is replaced with a mask given contexts. Although simpler and computationally efficient pretraining…

Computation and Language · Computer Science 2023-05-19 Atsuki Yamaguchi , Hiroaki Ozaki , Terufumi Morishita , Gaku Morio , Yasuhiro Sogawa

BERT adopts masked language modeling (MLM) for pre-training and is one of the most successful pre-training models. Since BERT neglects dependency among predicted tokens, XLNet introduces permuted language modeling (PLM) for pre-training to…

Computation and Language · Computer Science 2020-11-03 Kaitao Song , Xu Tan , Tao Qin , Jianfeng Lu , Tie-Yan Liu

Masked Language Modeling (MLM) has proven to be an essential component of Vision-Language (VL) pretraining. To implement MLM, the researcher must make two design choices: the masking strategy, which determines which tokens to mask, and the…

Machine Learning · Computer Science 2022-12-13 Siddharth Verma , Yuchen Lu , Rui Hou , Hanchao Yu , Nicolas Ballas , Madian Khabsa , Amjad Almahairi

We propose to pre-train a unified language model for both autoencoding and partially autoregressive language modeling tasks using a novel training procedure, referred to as a pseudo-masked language model (PMLM). Given an input text with…

Computation and Language · Computer Science 2020-03-02 Hangbo Bao , Li Dong , Furu Wei , Wenhui Wang , Nan Yang , Xiaodong Liu , Yu Wang , Songhao Piao , Jianfeng Gao , Ming Zhou , Hsiao-Wuen Hon

Protein language models (PLMs) have demonstrated remarkable capabilities in learning relationships between protein sequences and functions. However, finetuning these large models requires substantial computational resources, often with…

Machine Learning · Computer Science 2025-12-09 Shuo Zhang , Jian K. Liu

Masked language modeling (MLM) pre-training models such as BERT corrupt the input by replacing some tokens with [MASK] and then train a model to reconstruct the original tokens. This is an effective technique which has led to good results…

Computation and Language · Computer Science 2020-06-11 Andy Wagner , Tiyasa Mitra , Mrinal Iyer , Godfrey Da Costa , Marc Tremblay

We present EB-JEPA, an open-source library for learning representations and world models using Joint-Embedding Predictive Architectures (JEPAs). JEPAs learn to predict in representation space rather than pixel space, avoiding the pitfalls…

Computer Vision and Pattern Recognition · Computer Science 2026-04-09 Basile Terver , Randall Balestriero , Megi Dervishi , David Fan , Quentin Garrido , Tushar Nagarajan , Koustuv Sinha , Wancong Zhang , Mike Rabbat , Yann LeCun , Amir Bar

We study whether 3D self-supervised pretraining with Point--JEPA enables label-efficient grasp joint-angle prediction. Meshes are sampled to point clouds and tokenized; a ShapeNet-pretrained Point--JEPA encoder feeds a $K{=}5$…

Robotics · Computer Science 2025-09-26 Jed Guzelkabaagac , Boris Petrović

The Joint-Embedding Predictive Architecture (JEPA) is often seen as a non-generative alternative to likelihood-based self-supervised learning, emphasizing prediction in representation space rather than reconstruction in observation space.…

Machine Learning · Computer Science 2026-03-23 Moritz Gögl , Christopher Yau