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Background: Enlargement of perivascular spaces (PVS) is common in neurodegenerative disorders including cerebral small vessel disease, Alzheimer's disease, and Parkinson's disease. PVS enlargement may indicate impaired clearance pathways…

Image and Video Processing · Electrical Eng. & Systems 2025-02-17 William Pham , Alexander Jarema , Donggyu Rim , Zhibin Chen , Mohamed S. H. Khlif , Vaughan G. Macefield , Luke A. Henderson , Amy Brodtmann

All neuroimaging modalities have their own strengths and limitations. A current trend is toward interdisciplinary approaches that use multiple imaging methods to overcome limitations of each method in isolation. At the same time…

Methodology · Statistics 2023-03-30 Pratim Guha Niyogi , Martin A. Lindquist , Tapabrata Maiti

Cognitive modeling commonly relies on asking participants to complete a battery of varied tests in order to estimate attention, working memory, and other latent variables. In many cases, these tests result in highly variable observation…

This study introduces PV-RNN, a novel variational RNN inspired by the predictive-coding ideas. The model learns to extract the probabilistic structures hidden in fluctuating temporal patterns by dynamically changing the stochasticity of its…

Machine Learning · Computer Science 2019-06-26 Ahmadreza Ahmadi , Jun Tani

In the context of multivariate nonparametric regression with missing covariates, we propose Pattern Embedded Neural Networks (PENNs), which can be applied in conjunction with any existing imputation technique. In addition to a neural…

Methodology · Statistics 2025-04-30 Tianyi Ma , Tengyao Wang , Richard J. Samworth

While Reinforcement Learning from Verifiable Rewards (RLVR) has advanced reasoning in Large Vision-Language Models (LVLMs), prevailing frameworks suffer from a foundational methodological flaw: by distributing identical advantages across…

Artificial Intelligence · Computer Science 2026-04-09 Zekai Ye , Qiming Li , Xiaocheng Feng , Ruihan Chen , Ziming Li , Haoyu Ren , Kun Chen , Dandan Tu , Bing Qin

Hidden Markov models (HMMs) are probabilistic methods in which observations are seen as realizations of a latent Markov process with discrete states that switch over time. Moving beyond standard statistical tests, HMMs offer a statistical…

Methodology · Statistics 2024-03-20 S. Mildiner Moraga , E. Aarts

To understand how rich dynamics emerge in neural populations, we require models exhibiting a wide range of activity patterns while remaining interpretable in terms of connectivity and single-neuron dynamics. However, it has been challenging…

Neurons and Cognition · Quantitative Biology 2020-03-10 Alexandre René , André Longtin , Jakob H. Macke

Poisson-distributed latent variable models are widely used in computational neuroscience, but differentiating through discrete stochastic samples remains challenging. Two approaches address this: Exponential Arrival Time (EAT) simulation…

Machine Learning · Statistics 2026-02-05 Michael Ibrahim , Hanqi Zhao , Eli Sennesh , Zhi Li , Anqi Wu , Jacob L. Yates , Chengrui Li , Hadi Vafaii

We introduce the network model as a formal psychometric model, conceptualizing the covariance between psychometric indicators as resulting from pairwise interactions between observable variables in a network structure. This contrasts with…

Statistics Theory · Mathematics 2026-05-06 Sacha Epskamp , Mijke Rhemtulla , Denny Borsboom

Jointly identifying a mixture of discrete and continuous factors of variability without supervision is a key problem in unraveling complex phenomena. Variational inference has emerged as a promising method to learn interpretable mixture…

Machine Learning · Computer Science 2021-04-14 Yeganeh M. Marghi , Rohan Gala , Uygar Sümbül

In recent years, studies on image generation models of spiking neural networks (SNNs) have gained the attention of many researchers. Variational autoencoders (VAEs), as one of the most popular image generation models, have attracted a lot…

Computer Vision and Pattern Recognition · Computer Science 2024-10-28 Qiugang Zhan , Ran Tao , Xiurui Xie , Guisong Liu , Malu Zhang , Huajin Tang , Yang Yang

We study the problem of distributed adaptive estimation over networks where nodes cooperate to estimate physical parameters that can vary over both space and time domains. We use a set of basis functions to characterize the space-varying…

Systems and Control · Computer Science 2015-07-22 Reza Abdolee , Benoit Champagne , Ali H. Sayed

Brain-inspired learning models attempt to mimic the cortical architecture and computations performed in the neurons and synapses constituting the human brain to achieve its efficiency in cognitive tasks. In this work, we present…

Neural and Evolutionary Computing · Computer Science 2017-03-21 Priyadarshini Panda , Gopalakrishnan Srinivasan , Kaushik Roy

The performance of existing supervised neuron segmentation methods is highly dependent on the number of accurate annotations, especially when applied to large scale electron microscopy (EM) data. By extracting semantic information from…

Computer Vision and Pattern Recognition · Computer Science 2023-10-09 Yinda Chen , Wei Huang , Shenglong Zhou , Qi Chen , Zhiwei Xiong

While autoregressive Large Vision-Language Models (LVLMs) demonstrate remarkable proficiency in multimodal tasks, they face a "Visual Signal Dilution" phenomenon, where the accumulation of textual history expands the attention partition…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Siyuan Huang , Xiaoye Qu , Yafu Li , Tong Zhu , Zefeng He , Muxin Fu , Daizong Liu , Wei-Long Zheng , Yu Cheng

Physics-Informed Neural Networks (PINNs) offer a flexible framework for solving nonlinear partial differential equations (PDEs), yet conventional implementations often fail to preserve key physical invariants during long-term integration.…

Machine Learning · Computer Science 2025-11-04 Victory Obieke , Emmanuel Oguadimma

Behavior of neural networks is irremediably determined by the specific loss and data used during training. However it is often desirable to tune the model at inference time based on external factors such as preferences of the user or…

Computer Vision and Pattern Recognition · Computer Science 2023-04-04 Matteo Maggioni , Thomas Tanay , Francesca Babiloni , Steven McDonagh , Aleš Leonardis

Neurons in the nervous system convey information to higher brain regions by the generation of spike trains. An important question in the field of computational neuroscience is how these sensory neurons encode environmental information in a…

Neurons and Cognition · Quantitative Biology 2013-09-13 Alex Susemihl , Ron Meir , Manfred Opper

Many real-world datasets contain hidden structure that cannot be detected by simple linear correlations between input features. For example, latent factors may influence the data in a coordinated way, even though their effect is invisible…