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Data science plays a critical role in biomedical research, but it requires professionals with expertise in coding and medical data analysis. Large language models (LLMs) have shown great potential in supporting medical tasks and performing…

Artificial Intelligence · Computer Science 2025-04-10 Zifeng Wang , Benjamin Danek , Ziwei Yang , Zheng Chen , Jimeng Sun

The advancement of general medical Multimodal Large Language Models (MLLMs) has shown great potential for building conversational assistants to support clinical diagnosis. However, their adaptation to highly specialized domains such as…

Computer Vision and Pattern Recognition · Computer Science 2026-05-28 Xuanzhao Dong , Wenhui Zhu , Xiwen Chen , Hao Wang , Xin Li , Yujian Xiong , Jiajun Cheng , Jingjing Wang , Xiaobing Yu , Haiyu Wu , Shao Tang , Zhipeng Wang , Langechuan Liu , Shan Lin , Oana Dumitrascu , Yalin Wang

Large language models have demonstrated remarkable capabilities across a wide range of tasks, yet their ability to process structured symbolic knowledge remains underexplored. To address this gap, we propose a taxonomy of ontological…

Computation and Language · Computer Science 2025-10-03 Xiao Zhang , Huiyuan Lai , Qianru Meng , Johan Bos

While Multimodal Large Language Models (MLLMs) show promising performance in automated electrocardiogram interpretation, it remains unclear whether they genuinely perform actual step-by-step reasoning or just rely on superficial visual…

Machine Learning · Computer Science 2026-03-17 Jungwoo Oh , Hyunseung Chung , Junhee Lee , Min-Gyu Kim , Hangyul Yoon , Ki Seong Lee , Youngchae Lee , Muhan Yeo , Edward Choi

Developing large-scale foundational datasets is a critical milestone in advancing artificial intelligence (AI)-driven scientific innovation. However, unlike AI-mature fields such as natural language processing, materials science,…

Chemical Physics · Physics 2025-11-18 Ryo Yoshida , Yoshihiro Hayashi , Hidemine Furuya , Ryohei Hosoya , Kazuyoshi Kaneko , Hiroki Sugisawa , Yu Kaneko , Aiko Takahashi , Yoh Noguchi , Shun Nanjo , Keiko Shinoda , Tomu Hamakawa , Mitsuru Ohno , Takuya Kitamura , Misaki Yonekawa , Stephen Wu , Masato Ohnishi , Chang Liu , Teruki Tsurimoto , Arifin , Araki Wakiuchi , Kohei Noda , Junko Morikawa , Teruaki Hayakawa , Junichiro Shiomi , Masanobu Naito , Kazuya Shiratori , Tomoki Nagai , Norio Tomotsu , Hiroto Inoue , Ryuichi Sakashita , Masashi Ishii , Isao Kuwajima , Kenji Furuichi , Norihiko Hiroi , Yuki Takemoto , Takahiro Ohkuma , Keita Yamamoto , Naoya Kowatari , Masato Suzuki , Naoya Matsumoto , Seiryu Umetani , Hisaki Ikebata , Yasuyuki Shudo , Mayu Nagao , Shinya Kamada , Kazunori Kamio , Taichi Shomura , Kensaku Nakamura , Yudai Iwamizu , Atsutoshi Abe , Koki Yoshitomi , Yuki Horie , Katsuhiko Koike , Koichi Iwakabe , Shinya Gima , Kota Usui , Gikyo Usuki , Takuro Tsutsumi , Keitaro Matsuoka , Kazuki Sada , Masahiro Kitabata , Takuma Kikutsuji , Akitaka Kamauchi , Yusuke Iijima , Tsubasa Suzuki , Takenori Goda , Yuki Takabayashi , Kazuko Imai , Yuji Mochizuki , Hideo Doi , Koji Okuwaki , Hiroya Nitta , Taku Ozawa , Hitoshi Kamijima , Toshiaki Shintani , Takuma Mitamura , Massimiliano Zamengo , Yuitsu Sugami , Seiji Akiyama , Yoshinari Murakami , Atsushi Betto , Naoya Matsuo , Satoru Kagao , Tetsuya Kobayashi , Norie Matsubara , Shosei Kubo , Yuki Ishiyama , Yuri Ichioka , Mamoru Usami , Satoru Yoshizaki , Seigo Mizutani , Yosuke Hanawa , Shogo Kunieda , Mitsuru Yambe , Takeru Nakamura , Hiromori Murashima , Kenji Takahashi , Naoki Wada , Masahiro Kawano , Yosuke Harada , Takehiro Fujita , Erina Fujita , Ryoji Himeno , Hiori Kino , Kenji Fukumizu

In this paper, we introduce and apply Operations Research Question Answering (ORQA), a new benchmark designed to assess the generalization capabilities of Large Language Models (LLMs) in the specialized technical domain of Operations…

Comprehending occluded objects are not well studied in existing large-scale visual-language multi-modal models. Current state-of-the-art multi-modal large models struggles to provide satisfactory results in understanding occluded objects…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Chaoyi Wang , Baoqing Li , Xinhan Di

Causality is essential in scientific research, enabling researchers to interpret true relationships between variables. These causal relationships are often represented by causal graphs, which are directed acyclic graphs. With the recent…

Computation and Language · Computer Science 2025-02-19 Ivaxi Sheth , Bahare Fatemi , Mario Fritz

Organic reaction mechanisms are the stepwise elementary reactions by which reactants form intermediates and products, and are fundamental to understanding chemical reactivity and designing new molecules and reactions. Although large…

Artificial Intelligence · Computer Science 2026-05-05 Ruiling Xu , Yifan Zhang , Qingyun Wang , Carl Edwards , Heng Ji

Large Language Models (LLMs) excel in natural language tasks but still face challenges in Question Answering (QA) tasks requiring complex, multi-step reasoning. We outline the types of reasoning required in some of these tasks, and reframe…

Computation and Language · Computer Science 2025-02-17 Nick Ferguson , Liane Guillou , Alan Bundy , Kwabena Nuamah

Ontology matching (OM) plays an essential role in enabling semantic interoperability and integration across heterogeneous knowledge sources, particularly in the biomedical domain which contains numerous complex concepts related to diseases…

Artificial Intelligence · Computer Science 2026-04-03 Yiping Song , Jiaoyan Chen , Renate A. Schmidt

The advent of large language models (LLMs) has unlocked great opportunities in complex data management tasks, particularly in question answering (QA) over complicated multi-table relational data. Despite significant progress, systematically…

Artificial Intelligence · Computer Science 2024-12-02 Zipeng Qiu , You Peng , Guangxin He , Binhang Yuan , Chen Wang

Connecting text and visual modalities plays an essential role in generative intelligence. For this reason, inspired by the success of large language models, significant research efforts are being devoted to the development of Multimodal…

Computer Vision and Pattern Recognition · Computer Science 2024-06-07 Davide Caffagni , Federico Cocchi , Luca Barsellotti , Nicholas Moratelli , Sara Sarto , Lorenzo Baraldi , Lorenzo Baraldi , Marcella Cornia , Rita Cucchiara

Large language models (LLMs) have exhibited remarkable capabilities across various domains and tasks, pushing the boundaries of our knowledge in learning and cognition. The latest model, OpenAI's o1, stands out as the first LLM with an…

Computation and Language · Computer Science 2024-09-24 Yunfei Xie , Juncheng Wu , Haoqin Tu , Siwei Yang , Bingchen Zhao , Yongshuo Zong , Qiao Jin , Cihang Xie , Yuyin Zhou

Large language models (LLMs) are a class of artificial intelligence models based on deep learning, which have great performance in various tasks, especially in natural language processing (NLP). Large language models typically consist of…

Quantitative Methods · Quantitative Biology 2025-02-04 Jiajia Liu , Mengyuan Yang , Yankai Yu , Haixia Xu , Tiangang Wang , Kang Li , Xiaobo Zhou

In recent years, large language models (LLMs) have driven major advances in language understanding, marking a significant step toward artificial general intelligence (AGI). With increasing demands for higher-level semantics and cross-modal…

Computation and Language · Computer Science 2025-09-30 Yuntao Shou , Tao Meng , Wei Ai , Keqin Li

Large Language Models (LLMs) are increasingly used to answer everyday questions, yet their performance on culturally grounded and dialectal content remains uneven across languages. We propose a comprehensive method that (i) translates…

Computation and Language · Computer Science 2026-04-20 Hunzalah Hassan Bhatti , Firoj Alam

This paper presents MobQA, a benchmark dataset designed to evaluate the semantic understanding capabilities of large language models (LLMs) for human mobility data through natural language question answering. While existing models excel at…

Computation and Language · Computer Science 2025-08-18 Hikaru Asano , Hiroki Ouchi , Akira Kasuga , Ryo Yonetani

The rapid advancement of multi-modal language models (MLLMs) like GPT-4o has propelled the development of Omni language models, designed to process and proactively respond to continuous streams of multi-modal data. Despite their potential,…

Computer Vision and Pattern Recognition · Computer Science 2025-04-01 Yuxuan Wang , Yueqian Wang , Bo Chen , Tong Wu , Dongyan Zhao , Zilong Zheng

Handwritten mathematical expressions (HMEs) contain ambiguities in their interpretations, even for humans sometimes. Several math symbols are very similar in the writing style, such as dot and comma or 0, O, and o, which is a challenge for…

Computation and Language · Computer Science 2021-08-12 Huy Quang Ung , Cuong Tuan Nguyen , Hung Tuan Nguyen , Thanh-Nghia Truong , Masaki Nakagawa