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Large language models (LLMs) are having transformative impacts across a wide range of scientific fields, particularly in the biomedical sciences. Just as the goal of Natural Language Processing is to understand sequences of words, a major…

Genomics · Quantitative Biology 2024-09-24 Gonzalo Benegas , Chengzhong Ye , Carlos Albors , Jianan Canal Li , Yun S. Song

Whether Large Language Models (LLMs) truly possess human-like Theory of Mind (ToM) capabilities has garnered increasing attention. However, existing benchmarks remain largely restricted to narrow paradigms like false belief tasks, failing…

Artificial Intelligence · Computer Science 2026-01-23 Haibo Tong , Zeyang Yue , Feifei Zhao , Erliang Lin , Lu Jia , Ruolin Chen , Yinqian Sun , Qian Zhang , Yi Zeng

In real-world multimodal applications, systems usually need to comprehend arbitrarily combined and interleaved multimodal inputs from users, while also generating outputs in any interleaved multimedia form. This capability defines the goal…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Yanlin Li , Minghui Guo , Kaiwen Zhang , Shize Zhang , Yiran Zhao , Haodong Li , Congyue Zhou , Weijie Zheng , Yushen Yan , Shengqiong Wu , Wei Ji , Lei Cui , Furu Wei , Hao Fei , Mong-Li Lee , Wynne Hsu

Recent advances in Large Multi-modal Models (LMMs) have demonstrated their remarkable success as general-purpose multi-modal assistants, with particular focuses on holistic image- and video-language understanding. Conversely, less attention…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Ye Liu , Zongyang Ma , Junfu Pu , Zhongang Qi , Yang Wu , Ying Shan , Chang Wen Chen

Large Language Models (LLMs) offer new opportunities to accelerate complex interdisciplinary research domains. Epidemic modeling, characterized by its complexity and reliance on network science, dynamical systems, epidemiology, and…

Social and Information Networks · Computer Science 2026-02-26 Mohammad Hossein Samaei , Faryad Darabi Sahneh , Lee W. Cohnstaedt , Caterina Scoglio

Large Language Models (LLMs) are transforming scholarly tasks like search and summarization, but their reliability remains uncertain. Current evaluation metrics for testing LLM reliability are primarily automated approaches that prioritize…

Human-Computer Interaction · Computer Science 2026-02-25 Anna Martin-Boyle , William Humphreys , Martha Brown , Cara Leckey , Harmanpreet Kaur

Multimodal large language models (MLLMs) have shown remarkable performance in vision-language tasks. However, existing MLLMs are primarily trained on generic datasets, limiting their ability to reason on domain-specific visual cues such as…

Computer Vision and Pattern Recognition · Computer Science 2025-07-15 Hatef Otroshi Shahreza , Sébastien Marcel

Deploying Multimodal Large Language Models as the brain of embodied agents remains challenging, particularly under long-horizon observations and limited context budgets. Existing memory assisted methods often rely on textual summaries,…

Robotics · Computer Science 2026-03-03 Ji Li , Bo Wang , Jing Xia , Mingyi Li , Shiyan Hu

Recent advances in the audio language modeling (ALM) domain tackle audio understanding and text-to-audio generation as separate tasks. Very few studies attempt to unify these tasks -- an essential step toward advanced multimodal reasoning.…

As a prominent direction of Artificial General Intelligence (AGI), Multimodal Large Language Models (MLLMs) have garnered increased attention from both industry and academia. Building upon pre-trained LLMs, this family of models further…

Computer Vision and Pattern Recognition · Computer Science 2024-12-10 Chaoyou Fu , Yi-Fan Zhang , Shukang Yin , Bo Li , Xinyu Fang , Sirui Zhao , Haodong Duan , Xing Sun , Ziwei Liu , Liang Wang , Caifeng Shan , Ran He

Deep Language Models (DLMs) provide a novel computational paradigm for understanding the mechanisms of natural language processing in the human brain. Unlike traditional psycholinguistic models, DLMs use layered sequences of continuous…

Large language models (LLMs) and emerging agentic frameworks are beginning to transform single-cell biology by enabling natural-language reasoning, generative annotation, and multimodal data integration. However, progress remains fragmented…

Computation and Language · Computer Science 2025-11-25 Sajib Acharjee Dip , Adrika Zafor , Bikash Kumar Paul , Uddip Acharjee Shuvo , Muhit Islam Emon , Xuan Wang , Liqing Zhang

The swift advancement and widespread availability of foundational Large Language Models (LLMs), complemented by robust fine-tuning methodologies, have catalyzed their adaptation for innovative and industrious applications. Enabling LLMs to…

Computation and Language · Computer Science 2023-10-04 Eren Unlu

In the field of software operations, Large Language Models (LLMs) have attracted increasing attention. However, existing research has not yet achieved efficient and effective end-to-end intelligent operations due to low-quality data,…

Machine Learning · Computer Science 2026-05-13 Jingkai He , Pengfei Chen , Chenghui Wu , Shuang Liang , Ye Li , Gou Tan , Xiadao Wen , Chuanfu Zhang

Multimodal large language models (MLLMs) have shown strong vision-language reasoning abilities but still lack robust 3D spatial understanding, which is critical for autonomous driving. This limitation stems from two key challenges: (1) the…

Artificial Intelligence · Computer Science 2025-09-09 Ruixun Liu , Lingyu Kong , Derun Li , Hang Zhao

The pursuit of artificial general intelligence (AGI) has been accelerated by Multimodal Large Language Models (MLLMs), which exhibit superior reasoning, generalization capabilities, and proficiency in processing multimodal inputs. A crucial…

Computer Vision and Pattern Recognition · Computer Science 2024-06-12 Yi Chen , Yuying Ge , Yixiao Ge , Mingyu Ding , Bohao Li , Rui Wang , Ruifeng Xu , Ying Shan , Xihui Liu

Multimodal Large Language Models (MLLMs) have demonstrated proficiency in handling a variety of visual-language tasks. However, current MLLM benchmarks are predominantly designed to evaluate reasoning based on static information about a…

Computer Vision and Pattern Recognition · Computer Science 2024-01-26 Xiyao Wang , Yuhang Zhou , Xiaoyu Liu , Hongjin Lu , Yuancheng Xu , Feihong He , Jaehong Yoon , Taixi Lu , Gedas Bertasius , Mohit Bansal , Huaxiu Yao , Furong Huang

In an era defined by the explosive growth of data and rapid technological advancements, Multimodal Large Language Models (MLLMs) stand at the forefront of artificial intelligence (AI) systems. Designed to seamlessly integrate diverse data…

Retrieval augmented generation (RAG) has shown great power in improving Large Language Models (LLMs). However, most existing RAG-based LLMs are dedicated to retrieving single modality information, mainly text; while for many real-world…

Computation and Language · Computer Science 2025-06-09 Saptarshi Sengupta , Shuhua Yang , Paul Kwong Yu , Fali Wang , Suhang Wang

Recent advances in Multi-Modal Large Language Models (MLLMs) have enabled unified processing of language, vision, and structured inputs, opening the door to complex tasks such as logical deduction, spatial reasoning, and scientific…

Artificial Intelligence · Computer Science 2025-07-03 Guiyao Tie , Xueyang Zhou , Tianhe Gu , Ruihang Zhang , Chaoran Hu , Sizhe Zhang , Mengqu Sun , Yan Zhang , Pan Zhou , Lichao Sun
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