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Objective: While FLASH radiotherapy is recognized for short-term normal tissue sparing, its durability in late-responding organs remains uncertain, limiting clinical adoption. With its clinical importance and steep dose-response, the spinal…
Purpose: In this study, procedures were developed to achieve efficient reversible conversion of a clinical linear accelerator (LINAC) and deliver electron FLASH (eFLASH) or conventional beams to the treatment room isocenter. Material &…
An experimental and computational investigation of the space-charge effects occurring in ultrafast photoelectron spectroscopy from the gas phase is presented. The target sample CF$_3$I is excited by ultrashort (100 fs) far-ultraviolet…
Intense laser-driven proton pulses, inherently broadband and highly divergent, pose a challenge to established beamline concepts on the path to application-adapted irradiation field formation, particularly for 3D. Here we experimentally…
Radiotherapy is part of the treatment of over 50% of cancer patients. Its efficacy is limited by the radiotoxicity to the healthy tissue. FLASH-RT is based on the biological effect that ultra-high dose rates (UHDR) and very short treatment…
We have made observations of 98 low-Galactic-latitude pulsars to measure pulse broadening caused by multipath propagation through the interstellar medium. Data were collected with the 305-m Arecibo telescope at four radio frequencies…
We present nonlinear pulse compression of a high-power SESAM-modelocked thin-disk laser (TDL) using an Ar-filled hypocycloid-core Kagome Hollow-Core Photonic Crystal Fiber (HC-PCF). The output of the modelocked Yb:YAG TDL with 127 W average…
This paper presents an investigation of spectral properties of 10 millisecond pulsars (MSPs) discovered by the uGMRT, observed from 2017-2023 using band 3 (300-500 MHz) and 4 (550-750 MHz) of uGMRT. For these MSPs, we have reported a range…
Purpose: A diode EDGE Detector with a newly designed electrometer has been characterized for use in an UHDR electron beam and demonstrated appropriateness for UHDR FLASH radiotherapy dosimetry. Methods: Dose linearity, mean dose rate, and…
High peak-to-average power ratio (PAPR) is one of the main factors limiting cell coverage for cellular systems, especially in the uplink direction. Discrete Fourier transform spread orthogonal frequency-domain multiplexing (DFT-s-OFDM) with…
Monte Carlo (MC) is generally considered as the most accurate dose calculation tool for particle therapy. However, a proper description of the beam particles kinematics is a necessary input for a realistic simulation. Such a description can…
Objective: In this study, a fast imaging technique was developed for the first in vivo Cherenkov emission imaging from an ultra-high dose rate (UHDR) electron beam source at single pulse (360 Hz) submillimeter resolution. Approach: A CMOS…
The increasing interest in FLASH-RT has lead to the conversion of linear accelerators to enable ultra-high dose rate (UHDR) beams for preclinical research. Dosimetry hereof remains challenging with several crucial aspects missing. This work…
Ultrafast laser systems, those with a pulse duration on the order of picoseconds or less, have enabled advancements in a wide variety of fields. Of particular interest to this work, these laser systems are the key component to many High…
The successful operation of X-ray free-electron lasers (FELs), like the Linac Coherent Light Source or the Free-Electron Laser in Hamburg (FLASH), makes unprecedented research on matter at atomic length and ultrafast time scales possible.…
Metasurface based super absorbers exhibit near unity absorbance. While the absorption peak can be tuned by the geometry/size of the sub-wavelength resonator, broadband absorption can be obtained by placing multiple resonators of various…
Ultrafast lasers ($< 500$ fs) have enabled laser-matter interactions at intensities exceeding $10^{18} \rm{Wcm}^{-2}$ with only millijoules of laser energy. However, as pulse durations become shorter, larger spectral bandwidths are…
With an increase in the application of ultra-wideband (UWB) electromagnetic pulses in the communications industry, radar, biotechnology and medicine, comes an interest in UWB exposure safety standards. Despite an increase of the scientific…
Purpose: This study aims to investigate the impact of the beam temporal profile on the radical dynamics and inter-track interactions of FLASH radiotherapy, supporting parameter optimization for the equipment development and clinical…
Piezoelectric elastic metamaterials offer the ability to overcome the fixed, narrow bandwidth characteristics of passive elastic metamaterials. Interesting ultrasonic band gaps exist in piezoelectric plate metamaterials with periodic…