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Meta-analyses and systematic reviews demand rigorous abductive reasoning to build, test, and refine hypotheses across vast, heterogeneous literature. While NLP advancements have automated parts of this pipeline, existing tools often detach…

Human-Computer Interaction · Computer Science 2026-01-27 Sizhe Cheng , Feng Liang , Yuhan Wen , Xipei Yu , Yong Wang

Scientific discovery has long been constrained by human limitations in expertise, physical capability, and sleep cycles. The recent rise of AI scientists and automated laboratories has accelerated both the cognitive and operational aspects…

We introduce the STATION, an open-world multi-agent environment for autonomous scientific discovery. The Station simulates a complete scientific ecosystem, where agents can engage in long scientific journeys that include reading papers from…

Artificial Intelligence · Computer Science 2025-12-02 Stephen Chung , Wenyu Du

Recent progress in autonomous code generation has fueled excitement around AI agents capable of accelerating scientific discovery by running experiments. However, there is currently no benchmark that evaluates whether such agents can…

Artificial Intelligence · Computer Science 2025-06-25 Gyeongwon James Kim , Alex Wilf , Louis-Philippe Morency , Daniel Fried

Artificial intelligence (AI) is transforming the practice of science. Machine learning and large language models (LLMs) can generate hypotheses at a scale and speed far exceeding traditional methods, offering the potential to accelerate…

Artificial Intelligence · Computer Science 2025-12-18 Cristina Cornelio , Takuya Ito , Ryan Cory-Wright , Sanjeeb Dash , Lior Horesh

Experimental particle physics seeks to understand the universe by probing its fundamental particles and forces and exploring how they govern the large-scale processes that shape cosmic evolution. This whitepaper presents a vision for how…

High Energy Physics - Experiment · Physics 2026-02-20 Thea Klaeboe Aarrestad , Alaa Abdelhamid , Haider Abidi , Jahred Adelman , Jennifer Adelman-McCarthy , Shuchin Aeron , Garvita Agarwal , Usman Ali , Cristiano Alpigiani , Omar Alterkait , Mohamed Aly , Oz Amram , Saeed Ansari Fard , Aram Apyan , John Arrington , Marvin Ascencio-Sosa , Mohammad Atif , Aneesha Avasthi , Muhammad Bilal Azam , Bhim Bam , Joshua Barrow , Rainer Bartoldus , Amit Bashyal , Aashwin Basnet , Ayse Bat , Lothar A. T. Bauerdick , John Beacom , Chris Bee , Michael Begel , Matthew Bellis , Rene Bellwied , Rakitha Beminiwattha , Gabriele Benelli , Douglas Benjamin , Catrin Bernius , Binod Bhandari , Avinay Bhat , Meghna Bhattacharya , Saptaparna Bhattacharya , Prajita Bhattarai , Sudip Bhattarai , Wahid Bhimji , Jianming Bian , Burak Bilki , Mary Bishai , Kevin Black , Kenneth Bloom , Brian Bockelman , Johan Sebastian Bonilla Castro , Tulika Bose , Nilay Bostan , Othmane Bouhali , Dimitri Bourilkov , Dominic Brailsford , Gustaaf Brooijmans , Elizabeth Brost , Maria Brigida Brunetti , Quentin Buat , Brendon Bullard , Jackson Burzynski , Paolo Calafiura , Rodolfo Capdevilla , Fabian Andres Castaño Usuga , Raquel Castillo Fernandez , Fabio Catalano , Viviana Cavaliere , Flavio Cavanna , Giuseppe Cerati , Aidan Chambers , Maria Chamizo-Llatas , Philip Chang , Andrew Chappell , Arghya Chattopadhyay , Sergei Chekanov , Jian-ping Chen , Yi Chen , Zhengyang Chen , J. Taylor Childers , Hector Chinchay , Yuan-Tang Chou , Tasnuva Chowdhury , Neil Christensen , Wonyong Chung , Rafael Coelho Lopes de Sa , Simon Corrodi , Kyle Cranmer , Matteo Cremonesi , Roy Cruz , Mate Csanad , Mariarosaria D'Alfonso , Carlo Dallapiccola , Daine Danielson , Sridhara Dasu , Gavin Davies , Kaushik De , Patrick de Perio , Klaus Dehmelt , Marco Del Tutto , Carlos Ruben Dell'Aquila , Sarah Demers , Paolo Desiati , Bhesha Devkota , Sparshita Dey , Ranjan Dharmapalan , Karri Folan Di Petrillo , Markus Diefenthaler , Jeff Dillon , Zelimir Djurcic , Caterina Doglioni , Francois Drielsma , Edmond Dukes , Irene Dutta , Peter Elmer , Johannes Elmsheuser , Victor Daniel Elvira , Harold Evans , Peter Fackeldey , Cristiano Fanelli , Hao Fang , Mattia Fani , Muhammad Farooq , Matthew Feickert , Ian Fisk , Sam Foreman , Alexander Friedland , Nuwan Chaminda G. W. , Louis-Guillaume Gagnon , Massimiliano Galli , Abhijith Gandrakota , Sudeshna Ganguly , Arianna Garcia Caffaro , Rob Gardner , Rocky Bala Garg , Lino Gerlach , Aishik Ghosh , Romulus Godang , Julia Gonski , Loukas Gouskos , Richard Gran , Heather Gray , Andrei Gritsan , Gaia Grosso , Craig Group , Jiawei Guo , Shubham Gupta , Gajendra Gurung , Phillip Gutierrez , Oliver Gutsche , Tyler Hague , Joseph Haley , Eva Halkiadakis , Francis Halzen , Michael Hance , Philip Harris , Harry Hausner , Karsten Heeger , Lukas Heinrich , Alexander Held , Matthew Herndon , Ken Herner , Max Herrmann , David Hertzog , Christian Herwig , Aaron Higuera , Alexander Himmel , Timothy Hobbs , Stefan Hoeche , Tova Holmes , Tae Min Hong , Ben Hooberman , Walter Hopkins , Jessica N. Howard , Shih-Chieh Hsu , Fengping Hu , Patrick Huber , Dirk Hufnagel , Daniel Humphreys , Ia Iashvili , Joseph Incandela , Josh Isaacson , Wasikul Islam , Kirill Ivanov , Wooyoung Jang , Naomi Jarvis , Brij Kishor Jashal , Pratik Jawahar , Dulitha Jayakodige , Torri Jeske , Sergo Jindariani , Jay Hyun Jo , Bhishm Shankar Joshi , Xiangyang Ju , Andreas Jung , Thomas Junk , Michael Kagan , Daisy Kalra , Matthias Kaminski , Edward Karavakis , Stefan Katsarov , Stergios Kazakos , Paul King , Michael Kirby , Max Knobbe , Young Ju Ko , Dmitry Kondratyev , Rostislav Konoplich , Charis Koraka , Scott Kravitz , Lukas Kretschmann , Brandon Kriesten , Georgios K Krintiras , Iason Krommydas , Michelle Kuchera , Audrey Kvam , Martin Kwok , Theodota Lagouri , Sabine Lammers , Eric Lancon , Greg Landsberg , David Lange , Kevin Lannon , Joseph Lau , Luca Lavezzo , Benjamin Lawrence-Sanderson , Duc-Truyen Le , Matt LeBlanc , Sung-Won Lee , Trevin Lee , Charles Leggett , Kayla Leonard DeHolton , James Letts , Hao Li , Haoyang Li , Aklima Khanam Lima , Guilherme Lima , Mia Liu , Qibin Liu , Yinrui Liu , Zhen Liu , Shivani Lomte , Guillermo Loustau de Linares , Lu Lu , Pietro Lugato , Adam Lyon , Yang Ma , Christopher Madrid , Akhtar Mahmood , Kendall Mahn , Devin Mahon , Akshay Malige , Sudhir Malik , Abhishikth Mallampalli , Yurii Maravin , Ralph Marinaro , Pete Markowitz , Matthew Maroun , Kyla Martinez , Verena Ingrid Martinez Outschoorn , Sanjit Masanam , Mario Masciovecchio , Konstantin Matchev , Malek Mazouz , Simone Mazza , Thomas McCauley , Shawn McKee , Karim Mehrabi , Poonam Mehta , Andrew Melo , Mark Messier , Elias Mettner , Christopher Meyer , Jessie Micallef , Sophie Middleton , David W. Miller , Hamlet Mkrtchyan , Abdollah Mohammadi , Abhinav Mohan , Ajit Mohapatra , Farouk Mokhtar , Peter Monaghan , Claudio Silverio Montanari , Michael Mooney , Casey Morean , Eric Moreno , Alexander Moreno Briceño , Stephen Mrenna , Justin Mueller , Daniel Murnane , Benjamin Nachman , Emilio Nanni , Nitish Nayak , Miquel Nebot-Guinot , Orgho Neogi , Chris Neu , Mark Neubauer , Norbert Neumeister , Harvey Newman , Duong Nguyen , Gavin Niendorf , Paul Nilsson , Scarlet Norberg , Andrzej Novak , Sungbin Oh , Isabel Ojalvo , Olaiya Olokunboyo , Yasar Onel , Joseph Osborn , Ianna Osborne , Arantza Oyanguren , Nurcan Ozturk , Paul Padley , Simone Pagan Griso , Pritam Palit , Bishnu Pandey , Vishvas Pandey , Zisis Papandreou , Ganesh Parida , Ki Ryeong Park , Ajib Paudel , Manfred Paulini , Christoph Paus , Gregory Pawloski , Kevin Pedro , Gabriel Perdue , Troels Christian Petersen , Alexey Petrov , Deborah Pinna , Marc-André Pleier , Andrea Pocar , Prafull Purohit , Nived Puthumana Meleppattu , Mateusz Płoskoń , Sitian Qian , Xin Qian , Geting Qin , Aleena Rafique , Srini Rajagopalan , Dylan Rankin , Rebecca Rapp , Salvatore Rappoccio , Rohit Raut , Sagar Regmi , Benedikt Riedel , Andres Rios-Tascon , Stephen Roche , Jenna Roderick , Rimsky Rojas , Dmitry Romanov , Subhojit Roy , Rita Sadek , Dikshant Sagar , Nihar Ranjan Sahoo , Tai Sakuma , Juan Pablo Salas , Mayly Sanchez , Jay Sandesara , Alexander Savin , Ryan Schmitz , Kate Scholberg , Henry Schreiner , Reinhard Schwienhorst , Gabriella Sciolla , Saba Sehrish , Seon-Hee , Seo , Elizabeth Sexton-Kennedy , Oksana Shadura , Bijaya Sharma , Varun Sharma , Suyog Shrestha , Ryan Simeon , Jack Simoni , Siddharth Singh , Kim Siyeon , Louise Skinnari , Jinseop Song , Simone Sottocornola , Alexandre Sousa , Sairam Sri Vatsavai , Giordon Stark , Justin Stevens , Tyler Stokes , Nadja Strobbe , Indara Suarez , Manjukrishna Suresh , Andrew Sutton , Holly Szumila-Vance , Vardan Tadevosyan , Anyes Taffard , Buddhiman Tamang , Hirohisa Tanaka , Erdinch Tatar , Abdel Nasser Tawfik , Vikas Teotia , Kazuhiro Terao , Mitanshu Thakore , Jesse Thaler , Ameya Thete , Inar Timiryasov , Anthony Timmins , Andrew Toler , Dat Tran , Nhan Tran , Patrick Tsang , Ho Fung Tsoi , Vakho Tsulaia , Pham Tuan , Christopher Tully , Shengquan Tuo , Richard Tyson , Darren Upton , Hilary Utaegbulam , Zoya Vallari , Peter van Gemmeren , Vassil Vassilev , Nikhilesh Venkatasubramanian , Renzo Vizarreta , Emmanouil Vourliotis , Ilija Vukotic , Carl Vuosalo , Liv Våge , Tammy Walton , Linyan Wan , Biao Wang , Gensheng Wang , Michael Wang , Yuxuan Wang , Gordon Watts , Yingjie Wei , Derek Weitzel , Shawn Westerdale , Andrew White , Leigh Whitehead , Michael Wilking , Mike Williams , Stephane Willocq , Jeffery Winkler , Frank Winklmeier , Holger Witte , Peter Wittich , Douglas Wright , Yongcheng Wu , Yujun Wu , Wei Xie , Fang Xu , Barbara Yaeggy , Zhen Yan , Liang Yang , Wei Yang , Alejandro Yankelevich , Yiheng Ye , Oguzhan Yer , Efe Yigitbasi , Shin-Shan Yu , Jon Zarling , Chao Zhang , Licheng Zhang , Larry Zhao , Junjie Zhu , Jure Zupan

Computational experiments have become essential for scientific discovery, allowing researchers to test hypotheses, analyze complex datasets, and validate findings. However, as computational experiments grow in scale and complexity, ensuring…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-04-03 Eleni Adamidi , Panayiotis Deligiannis , Nikos Foutris , Thanasis Vergoulis

Artificial intelligence (AI) agents are emerging as transformative tools in drug discovery, with the ability to autonomously reason, act, and learn through complicated research workflows. Building on large language models (LLMs) coupled…

One of the grand challenges of artificial general intelligence is developing agents capable of conducting scientific research and discovering new knowledge. While frontier models have already been used as aides to human scientists, e.g. for…

Artificial Intelligence · Computer Science 2024-09-04 Chris Lu , Cong Lu , Robert Tjarko Lange , Jakob Foerster , Jeff Clune , David Ha

We present Claw AI Lab, a lab-native autonomous research platform that advances automated research from a hidden prompt-to-paper pipeline into an interactive AI laboratory. Rather than centering the system around a single agent or a fixed…

Artificial Intelligence · Computer Science 2026-05-22 Fan Wu , Cheng Chen , Zhenshan Tan , Taiyu Zhang , Xinzhen Xu , Yanyu Qian , Dingcheng Gao , Lanyun Zhu , Qi Zhu , Yi Tan , Deyi Ji , Guosheng Lin , Tianrun Chen , Deheng Ye , Fayao Liu

Experiential AI is proposed as a new research agenda in which artists and scientists come together to dispel the mystery of algorithms and make their mechanisms vividly apparent. It addresses the challenge of finding novel ways of opening…

Computers and Society · Computer Science 2019-08-08 Drew Hemment , Ruth Aylett , Vaishak Belle , Dave Murray-Rust , Ewa Luger , Jane Hillston , Michael Rovatsos , Frank Broz

Background: Everything as Code (EaC) is an emerging paradigm aiming to codify all aspects of modern software systems. Despite its growing popularity, comprehensive industry standards and peer-reviewed research clarifying its scope and…

Software Engineering · Computer Science 2025-07-08 Haoran Wei , Nazim Madhavji , John Steinbacher

Machine learning has emerged as a powerful tool for scientific discovery, enabling researchers to extract meaningful insights from complex datasets. For instance, it has facilitated the identification of disease-predictive genes from gene…

European Law now requires AI to be explainable in the context of adverse decisions affecting European Union (EU) citizens. At the same time, it is expected that there will be increasing instances of AI failure as it operates on imperfect…

Artificial Intelligence · Computer Science 2019-08-28 J. L. Olds , M. S. Khan , M. Nayebpour , N. Koizumi

AI-based systems, currently driven largely by LLMs and tool-using agentic harnesses, are increasingly discussed as a possible threat to software engineering. Foundation models get stronger, agents can plan and act across multiple steps, and…

Software Engineering · Computer Science 2026-04-24 Robert Feldt , Per Lenberg , Julian Frattini , Dhasarathy Parthasarathy

Historically, scientific discovery has been a lengthy and costly process, demanding substantial time and resources from initial conception to final results. To accelerate scientific discovery, reduce research costs, and improve research…

Human-Computer Interaction · Computer Science 2025-06-18 Samuel Schmidgall , Yusheng Su , Ze Wang , Ximeng Sun , Jialian Wu , Xiaodong Yu , Jiang Liu , Michael Moor , Zicheng Liu , Emad Barsoum

AI agentic programming is an emerging paradigm where large language model (LLM)-based coding agents autonomously plan, execute, and interact with tools such as compilers, debuggers, and version control systems. Unlike conventional code…

Software Engineering · Computer Science 2025-09-16 Huanting Wang , Jingzhi Gong , Huawei Zhang , Jie Xu , Zheng Wang

Artificial intelligence (AI) methods are poised to revolutionize intellectual work, with generative AI enabling automation of text analysis, text generation, and simple decision making or reasoning. The impact to science is only just…

Artificial Intelligence · Computer Science 2024-08-16 Kevin G. Yager

The process of scientific discovery relies on an interplay of observations, analysis, and hypothesis generation. Machine learning is increasingly being adopted to address individual aspects of this process. However, it remains an open…

Artificial Intelligence · Computer Science 2026-05-26 Maximilian Nägele , Florian Marquardt

Agentic systems, in which diverse agents cooperate to tackle challenging problems, are exploding in popularity in the AI community. However, existing agentic frameworks take a relatively narrow view of agents, apply a centralized model, and…

Multiagent Systems · Computer Science 2026-01-30 Alok Kamatar , J. Gregory Pauloski , Yadu Babuji , Ryan Chard , Mansi Sakarvadia , Daniel Babnigg , Kyle Chard , Ian Foster