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Several studies showed that Large Language Models (LLMs) can answer medical questions correctly, even outperforming the average human score in some medical exams. However, to our knowledge, no study has been conducted to assess the ability…

Computation and Language · Computer Science 2025-01-03 Asma Ben Abacha , Wen-wai Yim , Yujuan Fu , Zhaoyi Sun , Meliha Yetisgen , Fei Xia , Thomas Lin

Autonomous agents based on Large Language Models (LLMs) are increasingly being utilized in complex software systems. However, reliability remains a significant challenge due to unpredictable failures such as hallucinations, execution…

Software Engineering · Computer Science 2026-05-11 Cheonsu Jeong , Younggun Shin

Large language models (LLMs) are increasingly explored as scalable tools for mental health counseling, yet evaluating their safety remains challenging due to the interactional and context-dependent nature of clinical harm. Existing…

Computation and Language · Computer Science 2026-04-21 Suhyun Lee , Palakorn Achananuparp , Neemesh Yadav , Ee-Peng Lim , Yang Deng

We present a framework for the automated measurement of responsible AI (RAI) metrics for large language models (LLMs) and associated products and services. Our framework for automatically measuring harms from LLMs builds on existing…

Large language models (LLMs) offer transformative potential for clinical decision support in spine surgery but pose significant risks through hallucinations, which are factually inconsistent or contextually misaligned outputs that may…

Machine Learning · Computer Science 2025-11-21 Dong Chen , Yanzhe Wei , Zonglin He , Guan-Ming Kuang , Canhua Ye , Meiru An , Huili Peng , Yong Hu , Huiren Tao , Kenneth MC Cheung

Generating discharge summaries is a crucial yet time-consuming task in clinical practice, essential for conveying pertinent patient information and facilitating continuity of care. Recent advancements in large language models (LLMs) have…

Computation and Language · Computer Science 2025-07-01 Yiming Li , Fang Li , Kirk Roberts , Licong Cui , Cui Tao , Hua Xu

Frontier large language models (LLMs), such as GPT-5, Claude 4.5, Gemini 3, Llama 4, and DeepSeek-R1, represent a transformative class of AI tools capable of revolutionizing various aspects of healthcare by generating human-like responses…

Despite the growing use of large language models (LLMs) in clinical dialogue systems, existing evaluations focus on task completion or fluency, offering little insight into the behavioral and risk management requirements essential for…

While the deployment of large language models (LLMs) in high-value industries continues to expand, the systematic assessment of their safety against jailbreak and prompt-based attacks remains insufficient. Existing safety evaluation…

Cryptography and Security · Computer Science 2025-12-09 Xiuyuan Chen , Jian Zhao , Yuxiang He , Yuan Xun , Xinwei Liu , Yanshu Li , Huilin Zhou , Wei Cai , Ziyan Shi , Yuchen Yuan , Tianle Zhang , Chi Zhang , Xuelong Li

Accurate symptom-to-disease classification and clinically grounded treatment recommendations remain challenging, particularly in heterogeneous patient settings with high diagnostic risk. Existing large language model (LLM)-based systems…

Safety evaluations of large language models (LLMs) typically focus on universal risks like dangerous capabilities or undesirable propensities. However, millions use LLMs for personal advice on high-stakes topics like finance and health,…

Artificial Intelligence · Computer Science 2026-04-21 Manon Kempermann , Sai Suresh Macharla Vasu , Mahalakshmi Raveenthiran , Theo Farrell , Ingmar Weber

Medical systematic reviews play a vital role in healthcare decision making and policy. However, their production is time-consuming, limiting the availability of high-quality and up-to-date evidence summaries. Recent advancements in large…

Computation and Language · Computer Science 2023-10-19 Hye Sun Yun , Iain J. Marshall , Thomas A. Trikalinos , Byron C. Wallace

The rapid advancement and deployment of AI systems have created an urgent need for standard safety-evaluation frameworks. This paper introduces AILuminate v1.0, the first comprehensive industry-standard benchmark for assessing AI-product…

Computers and Society · Computer Science 2025-04-22 Shaona Ghosh , Heather Frase , Adina Williams , Sarah Luger , Paul Röttger , Fazl Barez , Sean McGregor , Kenneth Fricklas , Mala Kumar , Quentin Feuillade--Montixi , Kurt Bollacker , Felix Friedrich , Ryan Tsang , Bertie Vidgen , Alicia Parrish , Chris Knotz , Eleonora Presani , Jonathan Bennion , Marisa Ferrara Boston , Mike Kuniavsky , Wiebke Hutiri , James Ezick , Malek Ben Salem , Rajat Sahay , Sujata Goswami , Usman Gohar , Ben Huang , Supheakmungkol Sarin , Elie Alhajjar , Canyu Chen , Roman Eng , Kashyap Ramanandula Manjusha , Virendra Mehta , Eileen Long , Murali Emani , Natan Vidra , Benjamin Rukundo , Abolfazl Shahbazi , Kongtao Chen , Rajat Ghosh , Vithursan Thangarasa , Pierre Peigné , Abhinav Singh , Max Bartolo , Satyapriya Krishna , Mubashara Akhtar , Rafael Gold , Cody Coleman , Luis Oala , Vassil Tashev , Joseph Marvin Imperial , Amy Russ , Sasidhar Kunapuli , Nicolas Miailhe , Julien Delaunay , Bhaktipriya Radharapu , Rajat Shinde , Tuesday , Debojyoti Dutta , Declan Grabb , Ananya Gangavarapu , Saurav Sahay , Agasthya Gangavarapu , Patrick Schramowski , Stephen Singam , Tom David , Xudong Han , Priyanka Mary Mammen , Tarunima Prabhakar , Venelin Kovatchev , Rebecca Weiss , Ahmed Ahmed , Kelvin N. Manyeki , Sandeep Madireddy , Foutse Khomh , Fedor Zhdanov , Joachim Baumann , Nina Vasan , Xianjun Yang , Carlos Mougn , Jibin Rajan Varghese , Hussain Chinoy , Seshakrishna Jitendar , Manil Maskey , Claire V. Hardgrove , Tianhao Li , Aakash Gupta , Emil Joswin , Yifan Mai , Shachi H Kumar , Cigdem Patlak , Kevin Lu , Vincent Alessi , Sree Bhargavi Balija , Chenhe Gu , Robert Sullivan , James Gealy , Matt Lavrisa , James Goel , Peter Mattson , Percy Liang , Joaquin Vanschoren

The emergence of large language models (LLMs) has significantly influenced numerous fields, including healthcare, by enhancing the capabilities of automated systems to process and generate human-like text. However, despite their…

Information Retrieval · Computer Science 2025-04-23 Mohit Gupta , Akiko Aizawa , Rajiv Ratn Shah

The integration of Large Language Models (LLMs) into software engineering has revolutionized code generation, enabling unprecedented productivity through promptware and autonomous AI agents. However, this transformation introduces…

Software Engineering · Computer Science 2025-08-19 Satyam Kumar Navneet , Joydeep Chandra

Software engineers in various industrial domains are already using Large Language Models (LLMs) to accelerate the process of implementing parts of software systems. When considering its potential use for ADAS or AD systems in the automotive…

Software Engineering · Computer Science 2025-05-27 Ali Nouri , Beatriz Cabrero-Daniel , Zhennan Fei , Krishna Ronanki , Håkan Sivencrona , Christian Berger

Background: Large Language Models (LLMs) are transforming artificial intelligence applications in healthcare due to their ability to understand, generate, and summarize complex medical text. They offer valuable support to clinicians,…

Computation and Language · Computer Science 2026-04-14 Subin Santhosh , Farwa Abbas , Hussain Ahmad , Claudia Szabo

Physicians considering clinical trials for their patients are met with the laborious process of checking many text based eligibility criteria. Large Language Models (LLMs) have shown to perform well for clinical information extraction and…

Machine Learning · Computer Science 2023-06-30 Danny M. den Hamer , Perry Schoor , Tobias B. Polak , Daniel Kapitan

Large Language Models (LLMs) are increasingly used for cybersecurity threat analysis, but their deployment in security-sensitive environments raises trust and safety concerns. With over 21,000 vulnerabilities disclosed in 2025, manual…

Cryptography and Security · Computer Science 2025-09-04 Reza Fayyazi , Michael Zuzak , Shanchieh Jay Yang

The reliable evaluation of large language models (LLMs) in medical applications remains an open challenge, particularly in capturing the complexity of multi-turn doctor-patient interactions that unfold in real clinical environments.…

Artificial Intelligence · Computer Science 2025-10-15 Yuechun Yu , Han Ying , Haoan Jin , Wenjian Jiang , Dong Xian , Binghao Wang , Zhou Yang , Mengyue Wu