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Animal cells can sense chemical gradients without moving, and are faced with the challenge of migrating towards a target despite noisy information on the target position. Here we discuss optimal search strategies for a chaser that moves by…

Biological Physics · Physics 2015-03-18 Pawel Romanczuk , Guillaume Salbreux

The short-time dynamics of bacterial chromosomal loci is a mixture of subdiffusive and active motion, in the form of rapid relocations with near-ballistic dynamics. While previous work has shown that such rapid motions are ubiquitous, we…

Soft Condensed Matter · Physics 2017-10-11 Marco Gherardi , Ludovico Calabrese , Mikhail Tamm , Marco Cosentino Lagomarsino

Collective motion of chemotactic bacteria as E. Coli relies, at the individual level, on a continuous reorientation by runs and tumbles. It has been established that the length of run is decided by a stiff response to a temporal sensingof…

Analysis of PDEs · Mathematics 2018-08-15 Benoît Perthame , Shugo Yasuda

Understanding noisy information engines is a fundamental problem of non-equilibrium physics, particularly in biomolecular systems agitated by thermal and active fluctuations in the cell. By the generalized second law of thermodynamics, the…

Statistical Mechanics · Physics 2020-09-01 Govind Paneru , Sandipan Dutta , Takahiro Sagawa , Tsvi Tlusty , Hyuk Kyu Pak

We propose two nonlinear random walk models which are suitable for the analysis of both chemotaxis and anomalous transport. We derive the balance equations for the population density for the case when the transition rate for a random walk…

Statistical Mechanics · Physics 2010-10-22 Sergei Fedotov

The chemotactic pathway allows bacteria to respond and adapt to environmental changes, by tuning the tumbling and running motions that are due to clockwise and counterclockwise rotations of their flagella. The pathway is tightly regulated…

Molecular Networks · Quantitative Biology 2009-10-09 Daniela Besozzi , Paolo Cazzaniga , Matteo Dugo , Dario Pescini , Giancarlo Mauri

Cooperative search games are collective tasks where all agents share the same goal of reaching a target in the shortest time while limiting energy expenditure and avoiding collisions. Here we show that the equations that characterize the…

Biological Physics · Physics 2018-10-10 Alberto Pezzotta , Matteo Adorisio , Antonio Celani

Living cells often need to measure chemical concentrations that vary in time. To this end, they deploy many resources, e.g. receptors, downstream signaling molecules, time and energy. Here, we present a theory for the optimal design of a…

Molecular Networks · Quantitative Biology 2019-02-26 G. Malaguti , P. R. ten Wolde

Models for chemotaxis are based on gradient sensing of individual organisms. The key contribution of Keller and Segel is showing that erratic movements of individuals may result in an accurate chemotaxis phenomenon as a group. In this paper…

Populations and Evolution · Quantitative Biology 2013-07-31 Changwook Yoon , Yong-Jung Kim

Recent experiments on the green alga Chlamydomonas that swims using synchronized beating of a pair of flagella have revealed that it exhibits a run-and-tumble behavior similar to that of bacteria such as E. Coli. Using a simple purely…

Cell Behavior · Quantitative Biology 2015-06-12 Rachel R. Bennett , Ramin Golestanian

A simple model is studied for the chemotactic movement of biological cells in the presence of a periodic chemical wave. It incorporates the feature of adaptation that may play an important role in allowing for ``rectified" chemotaxis:…

Condensed Matter · Physics 2009-10-28 Raymond E. Goldstein

Active fluids refer to the fluids that contain self-propelled particles such as bacteria or micro-algae, whose properties differ fundamentally from the passive fluids. Such particles often exhibit an intermittent motion, with high-motility…

Biological Physics · Physics 2020-03-05 Thomas Vourc'h , Julien Léopoldès , Hassan Peerhossaini

Molecular communication is an expanding body of research. Recent advances in biology have encouraged using genetically engineered bacteria as the main component in the molecular communication. This has stimulated a new line of research that…

Information Theory · Computer Science 2012-09-13 Arash Einolghozati , Mohsen Sardari , Faramarz Fekr

Experiments have recently shown the feasibility of utilising bacteria as micro-scale robotic devices, with special attention paid to the development of bacteria-driven micro-swimmers taking advantage of built-in actuation and sensing…

Soft Condensed Matter · Physics 2019-02-14 Christian Esparza Lopez , Albane Thery , Eric Lauga

E. coli chemotactic motion in the presence of a chemoattractant field has been extensively studied using wet laboratory experiments, stochastic computational models as well as partial differential equation-based models (PDEs). The most…

Quantitative Methods · Quantitative Biology 2022-08-26 Yorgos M. Psarellis , Seungjoon Lee , Tapomoy Bhattacharjee , Sujit S. Datta , Juan M. Bello-Rivas , Ioannis G. Kevrekidis

Bacteria are easily characterizable model organisms with an impressively complicated set of capabilities. Among their capabilities is quorum sensing, a detailed cell-cell signaling system that may have a common origin with eukaryotic…

Neurons and Cognition · Quantitative Biology 2017-09-14 Archana Ram , Andrew Lo

We study single cell E.coli chemotaxis in a spatio-temporally varying attractant environment. Modeling the attractant concentration in the form of a traveling sine wave, we measure in our simulations, the chemotactic drift velocity of the…

Cell Behavior · Quantitative Biology 2025-06-06 Shobhan Dev Mandal , Sakuntala Chatterjee

Bacterial chemotaxis systems are as diverse as the environments that bacteria inhabit, but how much environmental variation can cells tolerate with a single system? Diversification of a single chemotaxis system could serve as an…

Populations and Evolution · Quantitative Biology 2015-11-30 Nicholas W Frankel , William Pontius , Yann S Dufour , Junjiajia Long , Luis Hernandez- Nunez , Thierry Emonet

In nature, microorganisms must often cope with hostile environmental conditions. To do so they have developed sophisticated cooperative behavior and intricate communication capabilities, such as: direct cell-cell physical interactions via…

Condensed Matter · Physics 2007-05-23 Eshel Ben-Jacob , Inon Cohen , Ido Golding , Yonathan Kozlovsky

Intelligent behavior in life-like systems often arises from the ability to gather, process, and act on information. While active matter provides a framework for studying life-like dynamics, it typically omits internal information-processing…

Statistical Mechanics · Physics 2026-03-02 Kristian Stølevik Olsen , Mitsusuke Tarama , Hartmut Löwen
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