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We study the performance of infotaxis search strategy measured by the rate of success and mean search time, under changes in the environment parameters such as diffusivity, rate of emission or wind velocity. We also investigate the drop of…

Emerging Technologies · Computer Science 2014-09-03 Juan Duque Rodríguez , David Gómez-Ullate , Carlos Mejía-Monasterio

Bacterial chemotaxis is one of the most extensively studied adaptive responses in cells. Many bacteria are able to bias their apparently random motion to produce a drift in the direction of the increasing chemoattractant concentration. It…

Soft Condensed Matter · Physics 2018-02-07 E. V. Pankratova , A. I. Kalyakulina , M. I. Krivonosov , S. Denisov , K. M. Taute , V. Yu. Zaburdaev

When cells measure concentrations of chemical signals, they may average multiple measurements over time in order to reduce noise in their measurements. However, when cells are in a environment that changes over time, past measurements may…

Cell Behavior · Quantitative Biology 2025-03-05 Aparajita Kashyap , Wei Wang , Brian A. Camley

Run-and-tumble motility is widely used by swimming microorganisms including numerous prokaryotic eukaryotic organisms. Here, we experimentally investigate the run-and-tumble dynamics of the bacterium E. coli in polymeric solutions. We find…

Fluid Dynamics · Physics 2015-11-04 A. E. Patteson , A. Gopinath , M. Goulian , P. E. Arratia

Microbiology is the science of microbes, particularly bacteria. Many bacteria are motile: they are capable of self-propulsion. Among these, a significant class execute so-called run-and-tumble motion: they follow a fairly straight path for…

Statistical Mechanics · Physics 2012-09-06 M. E. Cates

Biological systems like ciliated microorganisms are capable to respond to the external chemical gradients, a process known as chemotaxis which has been studied here using the chiral squirmer model. This theoretical model considers the…

Biological Physics · Physics 2018-04-18 Ruma Maity , P. S. Burada

Sensory systems have evolved to respond to input stimuli of certain statistical properties, and to reliably transmit this information through biochemical pathways. Hence, for an experimentally well-characterized sensory system, one ought to…

Cell Behavior · Quantitative Biology 2014-10-30 Diana Clausznitzer , Gabriele Micali , Silke Neumann , Victor Sourjik , Robert G. Endres

In the chemotactic motion of Escherichia coli, the switching of transmembrane chemoreceptors between active and inactive states is one of the most important steps of the signaling pathway. We study the effect of this switching time-scale on…

Cell Behavior · Quantitative Biology 2022-08-18 Shobhan Dev Mandal , Sakuntala Chatterjee

The classical macroscopic chemotaxis equations have previously been derived from an individual-based description of the tactic response of cells that use a "run-and-tumble" strategy in response to environmental cues. Here we derive…

Cell Behavior · Quantitative Biology 2007-05-23 Radek Erban , Hans G. Othmer

In many sensory systems, transmembrane receptors are spatially organized in large clusters. Such arrangement may facilitate signal amplification and the integration of multiple stimuli. However, this organization likely also affects the…

Molecular Networks · Quantitative Biology 2014-03-05 William Pontius , Michael W. Sneddon , Thierry Emonet

Information transmission in biological signaling circuits has often been described using the metaphor of a noise filter. Cellular systems need accurate, real-time data about their environmental conditions, but the biochemical reaction…

Molecular Networks · Quantitative Biology 2019-02-27 David Hathcock , James Sheehy , Casey Weisenberger , Efe Ilker , Michael Hinczewski

Chemotaxis enables marine bacteria to increase encounters with phytoplankton cells by reducing their search times, provided that bacteria detect noisy chemical gradients around phytoplankton. Gradient detection depends on bacterial…

Biological Physics · Physics 2025-01-14 Riccardo Foffi , Douglas R. Brumley , François Peaudecerf , Roman Stocker , Jonasz Słomka

Cells frequently employ extracellular vesicles, or exosomes, to signal across long distances and coordinate collective actions. Exosomes diffuse slowly, can be actively degraded, and contain stochastic amounts of molecular cargo. These…

Biological Physics · Physics 2025-10-15 Louis González , Andrew Mugler

Changes in a cell's external or internal conditions are usually reflected in the concentrations of the relevant transcription factors. These proteins in turn modulate the expression levels of the genes under their control and sometimes need…

Molecular Networks · Quantitative Biology 2013-08-01 Gasper Tkacik , Curtis G Callan , William Bialek

Run-and-tumble is a common but vital strategy that bacteria employ to explore environment suffused with boundaries, as well as to escape from entrapment. In this study we reveal how this strategy and the resulting dynamical behavior can be…

Soft Condensed Matter · Physics 2025-01-30 Premkumar Leishangthem , Xuan Wang , Junan Chen , Shengqi Yang , Xinliang Xu

We study chemotaxis of a single {\sl E.coli} bacterium in a medium where the nutrient chemical is also undergoing diffusion and its concentration has the form of a Gaussian whose width increases with time. We measure the average first…

Cell Behavior · Quantitative Biology 2015-04-30 Subrata Dev , Sakuntala Chatterjee

Motivated by observations of the dynamics of {\it Myxococcus xanthus}, we present a self-interacting random walk model that describes the competition between chemokinesis and chemotaxis. Cells are constrained to move in one dimension, but…

Statistical Mechanics · Physics 2016-08-31 Maria R. D'Orsogna , Marc Suchard , Tom Chou

Bacterial migration through confined spaces is critical for several phenomena like: biofilm formation, bacterial transport in soils, and bacterial therapy against cancer . In the present work, \textit{E. coli} (strain K12-MG1655 WT)…

Bacterial contamination of biological conducts, catheters or water resources is a major threat to public health and can be amplified by the ability of bacteria to swim upstream. The mechanisms of this rheotaxis, the reorientation with…

Soft Condensed Matter · Physics 2019-08-12 Arnold Mathijssen , Nuris Figueroa-Morales , Gaspard Junot , Eric Clement , Anke Lindner , Andreas Zöttl

Biomolecules stochastically occupy different possible configurations with probabilities given by non-equilibrium steady-state distributions. These distributions are determined by the transition rate constants between different…

Biological Physics · Physics 2024-07-19 Easun Arunachalam , Milo M. Lin
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