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Enhancing the precision of segmenting coronary atherosclerotic plaques from CT Angiography (CTA) images is pivotal for advanced Coronary Atherosclerosis Analysis (CAA), which distinctively relies on the analysis of vessel cross-section…

Image and Video Processing · Electrical Eng. & Systems 2025-01-15 Ziheng Zhang , Zihan Li , Dandan Shan , Yuehui Qiu , Qingqi Hong , Qingqiang Wu

Convolutional neural networks (CNN) for multi-class segmentation of medical images are widely used today. Especially models with multiple outputs that can separately predict segmentation classes (regions) without relying on a probabilistic…

Computer Vision and Pattern Recognition · Computer Science 2025-12-22 Denis Mikhailapov , Vladimir Berikov

Neural networks exhibit severe brittleness to semantically irrelevant transformations. A mere 75ms electrocardiogram (ECG) phase shift degrades latent cosine similarity from 1.0 to 0.2, while sensor rotations collapse activity recognition…

Machine Learning · Computer Science 2025-11-20 Zhengyang Shen , Hua Tu , Mayue Shi

Breast cancer, the most common malignancy among women, requires precise detection and classification for effective treatment. Immunohistochemistry (IHC) biomarkers like HER2, ER, and PR are critical for identifying breast cancer subtypes.…

Computer Vision and Pattern Recognition · Computer Science 2025-03-31 Ekansh Chauhan , Anila Sharma , Amit Sharma , Vikas Nishadham , Asha Ghughtyal , Ankur Kumar , Gurudutt Gupta , Anurag Mehta , C. V. Jawahar , P. K. Vinod

We propose a new approach, called cooperative neural networks (CoNN), which uses a set of cooperatively trained neural networks to capture latent representations that exploit prior given independence structure. The model is more flexible…

Machine Learning · Computer Science 2019-06-04 Harsh Shrivastava , Eugene Bart , Bob Price , Hanjun Dai , Bo Dai , Srinivas Aluru

A method of a Convolutional Neural Networks (CNN) for image classification with image preprocessing and hyperparameters tuning was proposed. The method aims at increasing the predictive performance for COVID-19 diagnosis while more complex…

Image and Video Processing · Electrical Eng. & Systems 2023-06-06 Kenan Morani , Devrim Unay

Accurate subtyping of renal cell carcinoma (RCC) is of crucial importance for understanding disease progression and for making informed treatment decisions. New discoveries of significant alterations to mitochondria between subtypes make…

Machine Learning · Computer Science 2016-08-03 Peter J. Schüffler , Judy Sarungbam , Hassan Muhammad , Ed Reznik , Satish K. Tickoo , Thomas J. Fuchs

Single-cell RNA sequencing (scRNA-seq) is powerful technology that allows researchers to understand gene expression patterns at the single-cell level. However, analysing scRNA-seq data is challenging due to issues and biases in data…

Genomics · Quantitative Biology 2023-12-14 Jinlu Liu , Sara Wade , Natalia Bochkina

An important part of breast cancer staging is the assessment of the sentinel axillary node for early signs of tumor spreading. However, this assessment by pathologists is not always easy and retrospective surveys often requalify the status…

Quantitative Methods · Quantitative Biology 2024-04-30 Eric Bonnet

Deep neural networks (DNNs) have been widely criticized for their overconfidence when dealing with out-of-distribution (OOD) samples, highlighting the critical need for effective OOD detection to ensure the safe deployment of DNNs in…

Computer Vision and Pattern Recognition · Computer Science 2025-03-17 Zhiwei Ling , Yachen Chang , Hailiang Zhao , Xinkui Zhao , Kingsum Chow , Shuiguang Deng

Colorectal cancer (CRC) grading is a critical prognostic factor but remains hampered by inter-observer variability and the privacy constraints of multi-institutional data sharing. While deep learning offers a path to automation, centralized…

The rapid adoption of transformer-based models in computational pathology has enabled prediction of molecular and clinical biomarkers from H&E whole-slide images, yet interpretability has not kept pace with model complexity. While…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Marco Gustav , Fabian Wolf , Christina Glasner , Nic G. Reitsam , Stefan Schulz , Kira Aschenbroich , Bruno Märkl , Sebastian Foersch , Jakob Nikolas Kather

Multi-label chest X-ray (CXR) recognition involves simultaneously diagnosing and identifying multiple labels for different pathologies. Since pathological labels have rich information about their relationship to each other, modeling the…

Computer Vision and Pattern Recognition · Computer Science 2023-02-23 Guoli Wang , Pingping Wang , Jinyu Cong , Kunmeng Liu , Benzheng Wei

The exploration of cellular heterogeneity within the tumor microenvironment (TME) via single-cell RNA sequencing (scRNA-seq) is essential for understanding cancer progression and response to therapy. Current scRNA-seq approaches, however,…

Genomics · Quantitative Biology 2025-02-06 Yu-An Huang , Yue-Chao Li , Hai-Ru You , Jie Pan , Xiyue Cao , Xinyuan Li , Zhi-An Huang , Zhu-Hong You

Background: Colorectal adenocarcinoma (CRC) remains a leading cause of cancer-related mortality worldwide, with variable patient outcomes despite treatment advances. Traditional prognostic methods based on clinicopathological variables…

Quantitative Methods · Quantitative Biology 2025-07-28 Oluwafemi Ogundare

The chest X-rays (CXRs) is one of the views most commonly ordered by radiologists (NHS),which is critical for diagnosis of many different thoracic diseases. Accurately detecting thepresence of multiple diseases from CXRs is still a…

Computer Vision and Pattern Recognition · Computer Science 2020-05-27 Hieu H. Pham , Tung T. Le , Dat T. Ngo , Dat Q. Tran , Ha Q. Nguyen

Chest radiograph (CXR) interpretation in pediatric patients is error-prone and requires a high level of understanding of radiologic expertise. Recently, deep convolutional neural networks (D-CNNs) have shown remarkable performance in…

Image and Video Processing · Electrical Eng. & Systems 2021-08-29 Thanh T. Tran , Hieu H. Pham , Thang V. Nguyen , Tung T. Le , Hieu T. Nguyen , Ha Q. Nguyen

It is feasible to recognize the presence and seriousness of eye disease by investigating the progressions in retinal biological structure. Fundus examination is a diagnostic procedure to examine the biological structure and anomaly of the…

Image and Video Processing · Electrical Eng. & Systems 2022-07-19 Amit Bhati , Neha Gour , Pritee Khanna , Aparajita Ojha

Analysing coronary artery plaque segments with respect to their functional significance and therefore their influence to patient management in a non-invasive setup is an important subject of current research. In this work we compare and…

Image and Video Processing · Electrical Eng. & Systems 2019-12-16 Felix Denzinger , Michael Wels , Katharina Breininger , Anika Reidelshöfer , Joachim Eckert , Michael Sühling , Axel Schmermund , Andreas Maier

Plant diseases pose a significant threat to global food security, necessitating accurate and interpretable disease detection methods. This study introduces an interpretable attention-guided Convolutional Neural Network (CNN), CBAM-VGG16,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-25 Balram Singh , Ram Prakash Sharma , Somnath Dey