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Due to cellular heterogeneity, cell nuclei classification, segmentation, and detection from pathological images are challenging tasks. In the last few years, Deep Convolutional Neural Networks (DCNN) approaches have been shown…

Computer Vision and Pattern Recognition · Computer Science 2018-11-09 Md Zahangir Alom , Chris Yakopcic , Tarek M. Taha , Vijayan K. Asari

Automated grading of diabetic retinopathy (DR) faces several critical challenges: subtle inter-grade visual distinctions in fine-grained lesion patterns, distributional discrepancies induced by heterogeneous imaging devices and acquisition…

Image and Video Processing · Electrical Eng. & Systems 2026-05-12 Yiqun Wang

Clusters of differentiation (CD) are cell surface biomarkers that denote key biological differences between cell types and disease state. CD-targeting therapeutic monoclonal antibodies (mAB) afford rich trans-disease repositioning…

Molecular Networks · Quantitative Biology 2018-03-14 Trang T. Le , Nigel O. Blackwood , Jaclyn N. Taroni , Weixuan Fu , Matthew K. Breitenstein

Recent advancements in protein design have leveraged diffusion models to generate structural scaffolds, followed by a process known as protein inverse folding, which involves sequence inference on these scaffolds. However, these…

Biomolecules · Quantitative Biology 2025-02-27 Xingyi Zhang , Kun Xie , Ningqiao Huang , Wei Liu , Peilin Zhao , Sibo Wang , Kangfei Zhao , Biaobin Jiang

Disease diagnosis on chest X-ray images is a challenging multi-label classification task. Previous works generally classify the diseases independently on the input image without considering any correlation among diseases. However, such…

Computer Vision and Pattern Recognition · Computer Science 2020-03-02 Daizong Liu , Shuangjie Xu , Pan Zhou , Kun He , Wei Wei , Zichuan Xu

Current state-of-the-art two-stage models on instance segmentation task suffer from several types of imbalances. In this paper, we address the Intersection over the Union (IoU) distribution imbalance of positive input Regions of Interest…

Computer Vision and Pattern Recognition · Computer Science 2024-04-26 Leonardo Rossi , Akbar Karimi , Andrea Prati

Relational learning deals with data that are characterized by relational structures. An important task is collective classification, which is to jointly classify networked objects. While it holds a great promise to produce a better accuracy…

Machine Learning · Computer Science 2016-11-30 Trang Pham , Truyen Tran , Dinh Phung , Svetha Venkatesh

Computed tomography (CT) enterography is a primary imaging modality for assessing inflammatory bowel disease (IBD), yet the representational choices that best support automated analysis of this modality are unknown. We present the first…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Cristian Minoccheri , Emily Wittrup , Kayvan Najarian , Ryan Stidham

Convolutional neural networks (CNNs) show impressive performance for image classification and detection, extending heavily to the medical image domain. Nevertheless, medical experts are sceptical in these predictions as the nonlinear…

Computer Vision and Pattern Recognition · Computer Science 2017-06-30 Waleed M. Gondal , Jan M. Köhler , René Grzeszick , Gernot A. Fink , Michael Hirsch

This study introduces the SHAP-integrated convolutional diagnostic network (SICDN), an interpretable feature selection method designed for limited datasets, to address the challenge posed by data privacy regulations that restrict access to…

Image and Video Processing · Electrical Eng. & Systems 2025-03-13 Yan Hu , Ahmad Chaddad

In this study, we proposed a model for skin disease classification using a Bilinear Convolutional Neural Network (BCNN) with a Constrained Triplet Network (CTN). BCNN can capture rich spatial interactions between features in image data.…

Computer Vision and Pattern Recognition · Computer Science 2024-06-04 Belal Ahmad , Mohd Usama , Tanvir Ahmad , Adnan Saeed , Shabnam Khatoon , Long Hu

Periorbital distances are critical markers for diagnosing and monitoring a range of oculoplastic and craniofacial conditions. Manual measurement, however, is subjective and prone to intergrader variability. Automated methods have been…

Accurate classification of blood cells is of vital significance in the diagnosis of hematological disorders. However, in real-world scenarios, domain shifts caused by the variability in laboratory procedures and settings, result in a rapid…

Computer Vision and Pattern Recognition · Computer Science 2024-08-15 Yongcheng Li , Lingcong Cai , Ying Lu , Cheng Lin , Yupeng Zhang , Jingyan Jiang , Genan Dai , Bowen Zhang , Jingzhou Cao , Xiangzhong Zhang , Xiaomao Fan

Objective: Optical coherence tomography (OCT) and its angiography (OCTA) have several advantages for the early detection and diagnosis of diabetic retinopathy (DR). However, automated, complete DR classification frameworks based on both OCT…

Image and Video Processing · Electrical Eng. & Systems 2020-09-28 Pengxiao Zang , Liqin Gao , Tristan T. Hormel , Jie Wang , Qisheng You , Thomas S. Hwang , Yali Jia

Single-cell sequencing has a significant role to explore biological processes such as embryonic development, cancer evolution, and cell differentiation. These biological properties can be presented by a two-dimensional scatter plot.…

Genomics · Quantitative Biology 2021-10-19 Ziyi Liu , Minghui Liao , Fulin luo , Bo Du

Accurate classification of lung diseases from chest CT scans plays an important role in computer-aided diagnosis systems. However, medical imaging datasets often suffer from severe class imbalance, which may significantly degrade the…

Image and Video Processing · Electrical Eng. & Systems 2026-03-18 Kejin Lu , Jianfa Bai , Qingqiu Li , Runtian Yuan , Jilan Xu , Junlin Hou , Yuejie Zhang , Rui Feng

Convolutional neural network (CNN) and recurrent neural network (RNN) models have become the mainstream methods for relation classification. We propose a unified architecture, which exploits the advantages of CNN and RNN simultaneously, to…

Computation and Language · Computer Science 2018-07-31 Bin He , Yi Guan , Rui Dai

Self supervised contrastive learning based pretraining allows development of robust and generalized deep learning models with small, labeled datasets, reducing the burden of label generation. This paper aims to evaluate the effect of CL…

Image and Video Processing · Electrical Eng. & Systems 2022-08-25 Minhaj Nur Alam , Rikiya Yamashita , Vignav Ramesh , Tejas Prabhune , Jennifer I. Lim , R. V. P. Chan , Joelle Hallak , Theodore Leng , Daniel Rubin

Colorectal cancer (CRC) is a leading worldwide cause of cancer-related mortality, and the role of prompt precise detection is of paramount interest in improving patient outcomes. Conventional diagnostic methods such as colonoscopy and…

Image and Video Processing · Electrical Eng. & Systems 2025-10-29 Ovi Sarkar , Md Shafiuzzaman , Md. Faysal Ahamed , Golam Mahmud , Muhammad E. H. Chowdhury

The COVID-19 pandemic exposed critical limitations in diagnostic workflows: RT-PCR tests suffer from slow turnaround times and high false-negative rates, while CT-based screening offers faster complementary diagnosis but requires expert…

Image and Video Processing · Electrical Eng. & Systems 2026-03-18 Aadit Nilay , Bhavesh Thapar , Anant Agrawal , Mohammad Nayeem Teli