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To effectively study complex causal systems, it is often useful to construct abstractions of parts of the system by discarding irrelevant details while preserving key features. The Information Bottleneck (IB) method is a widely used…

Machine Learning · Computer Science 2025-06-12 Francisco N. F. Q. Simoes , Mehdi Dastani , Thijs van Ommen

Instrumental variables (IVs) are widely used to estimate causal effects in the presence of unobserved confounding between exposure and outcome. An IV must affect the outcome exclusively through the exposure and be unconfounded with the…

We study the problem of globally optimizing the causal effect on a target variable of an unknown causal graph in which interventions can be performed. This problem arises in many areas of science including biology, operations research and…

Machine Learning · Computer Science 2022-08-26 Nicola Branchini , Virginia Aglietti , Neil Dhir , Theodoros Damoulas

Relational triple extraction is a fundamental task in the field of information extraction, and a promising framework based on table filling has recently gained attention as a potential baseline for entity relation extraction. However,…

Computation and Language · Computer Science 2024-03-05 Jianli Zhao , Changhao Xu , Bin Jiang

Distributed computation in artificial life and complex systems is often described in terms of component operations on information: information storage, transfer and modification. Information modification remains poorly described however,…

Information Theory · Computer Science 2013-10-10 Joseph T. Lizier , Benjamin Flecker , Paul L. Williams

In many scientific fields, the generation and evolution of data are governed by partial differential equations (PDEs) which are typically informed by established physical laws at the macroscopic level to describe general and predictable…

Methodology · Statistics 2025-07-01 Ziyuan Chen , Shunxing Yan , Fang Yao

Causal decomposition analyses can help build the evidence base for interventions that address health disparities (inequities). They ask how disparities in outcomes may change under hypothetical intervention. Through study design and…

Methodology · Statistics 2020-09-17 John W. Jackson

Causal inference often hinges on strong assumptions - such as no unmeasured confounding or perfect compliance - that are rarely satisfied in practice. Partial identification offers a principled alternative: instead of relying on…

Machine Learning · Computer Science 2025-08-20 Tobias Maringgele

In science, macro level descriptions of the causal interactions within complex, dynamical systems are typically deemed convenient, but ultimately reducible to a complete causal account of the underlying micro constituents. Yet, such a…

Neurons and Cognition · Quantitative Biology 2020-04-02 Larissa Albantakis , Francesco Massari , Maggie Beheler-Amass , Giulio Tononi

We propose an information-theoretic bias measurement technique through a causal interpretation of spurious correlation, which is effective to identify the feature-level algorithmic bias by taking advantage of conditional mutual information.…

Machine Learning · Computer Science 2022-01-11 Seonguk Seo , Joon-Young Lee , Bohyung Han

Neurobiological and neurodegenerative diseases are inherently multifactorial, arising from coupled influences spanning genetic susceptibility, brain alterations, and environmental and behavioral factors. Multimodal modeling has therefore…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Shaowen Wan , Yanjun Lv , Lu Zhang , Dajiang Zhu , Bharat Biswal , Tianming Liu , Xiaobo Li , Lin Zhao

Educational disparities are rooted in and perpetuate social inequalities across multiple dimensions such as race, socioeconomic status, and geography. To reduce disparities, most intervention strategies focus on a single domain and…

Methodology · Statistics 2026-04-17 Soojin Park , Su Yeon Kim , Xinyao Zheng , Chioun Lee

Graphical causal models led to the development of complete non-parametric identification theory in arbitrary structured systems, and general approaches to efficient inference. Nevertheless, graphical approaches to causal inference have not…

Methodology · Statistics 2021-11-02 AmirEmad Ghassami , Ilya Shpitser

Probabilities of causation are fundamental to individual-level explanation and decision making, yet they are inherently counterfactual and not point-identifiable from data in general. Existing bounds either disregard available covariates,…

Artificial Intelligence · Computer Science 2026-02-17 Yuxuan Xie , Ang Li

Originally developed as a theory of consciousness, integrated information theory provides a mathematical framework to quantify the causal irreducibility of systems and subsets of units in the system. Specifically, mechanism integrated…

Neurons and Cognition · Quantitative Biology 2024-04-23 Alireza Zaeemzadeh , Giulio Tononi

While estimation of the marginal (total) causal effect of a point exposure on an outcome is arguably the most common objective of experimental and observational studies in the health and social sciences, in recent years, investigators have…

Statistics Theory · Mathematics 2012-10-18 Eric J. Tchetgen Tchetgen , Ilya Shpitser

The class of problems in causal inference which seeks to isolate causal correlations solely from observational data even without interventions has come to the forefront of machine learning, neuroscience and social sciences. As new large…

Emerging Technologies · Computer Science 2022-01-02 Mohammad Ali Javidian , Vaneet Aggarwal , Fanglin Bao , Zubin Jacob

Complexity measures in the context of the Integrated Information Theory of consciousness try to quantify the strength of the causal connections between different neurons. This is done by minimizing the KL-divergence between a full system…

Methodology · Statistics 2021-02-09 Carlotta Langer , Nihat Ay

One of the fundamental steps toward understanding a complex system is identifying variation at the scale of the system's components that is most relevant to behavior on a macroscopic scale. Mutual information provides a natural means of…

Machine Learning · Computer Science 2024-03-20 Kieran A. Murphy , Dani S. Bassett

Analysis of observational studies increasingly confronts the challenge of determining which of a possibly high-dimensional set of available covariates are required to satisfy the assumption of ignorable treatment assignment for estimation…

Methodology · Statistics 2022-03-23 Chanmin Kim , Mauricio Tec , Corwin M Zigler