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Vessel segmentation of retinal images is a key diagnostic capability in ophthalmology. This problem faces several challenges including low contrast, variable vessel size and thickness, and presence of interfering pathology such as…

Image and Video Processing · Electrical Eng. & Systems 2020-02-19 Venkateswararao Cherukuri , Vijay Kumar BG , Raja Bala , Vishal Monga

Tracking the pose of instruments is a central problem in image-guided surgery. For microscopic scenarios, optical coherence tomography (OCT) is increasingly used as an imaging modality. OCT is suitable for accurate pose estimation due to…

Computer Vision and Pattern Recognition · Computer Science 2018-03-28 Nils Gessert , Matthias Schlüter , Alexander Schlaefer

Deep learning methods for ophthalmic diagnosis have shown considerable success in tasks like segmentation and classification. However, their widespread application is limited due to the models being opaque and vulnerable to making a wrong…

Image and Video Processing · Electrical Eng. & Systems 2021-01-29 Amitojdeep Singh , Sourya Sengupta , Mohammed Abdul Rasheed , Varadharajan Jayakumar , Vasudevan Lakshminarayanan

Every day, countless surgeries are performed worldwide, each within the distinct settings of operating rooms (ORs) that vary not only in their setups but also in the personnel, tools, and equipment used. This inherent diversity poses a…

Computer Vision and Pattern Recognition · Computer Science 2024-04-11 Ege Özsoy , Chantal Pellegrini , Matthias Keicher , Nassir Navab

Background: Cervical cancer seriously affects the health of the female reproductive system. Optical coherence tomography (OCT) emerged as a non-invasive, high-resolution imaging technology for cervical disease detection. However, OCT image…

Image and Video Processing · Electrical Eng. & Systems 2022-06-14 Kaiyi Chen , Qingbin Wang , Yutao Ma

Skin cancer is one of the most prevalent and potentially life-threatening diseases worldwide, necessitating early and accurate diagnosis to improve patient outcomes. Conventional diagnostic methods, reliant on clinical expertise and…

Computer Vision and Pattern Recognition · Computer Science 2025-01-28 Mirza Ahsan Ullah , Tehseen Zia

Anatomical understanding through deep learning is critical for automatic report generation, intra-operative navigation, and organ localization in medical imaging; however, its progress is constrained by the scarcity of expert-labeled data.…

Computer Vision and Pattern Recognition · Computer Science 2025-09-29 Yiwei Li , Yikang Liu , Jiaqi Guo , Lin Zhao , Zheyuan Zhang , Xiao Chen , Boris Mailhe , Ankush Mukherjee , Terrence Chen , Shanhui Sun

Accurate segmentation of macular edema, a hallmark pathological feature in vision-threatening conditions such as age-related macular degeneration and diabetic macular edema, is essential for clinical diagnosis and management. To overcome…

Computer Vision and Pattern Recognition · Computer Science 2025-12-29 Li Yang , Yuting Liu

In recent years, the incidence of vision-threatening eye diseases has risen dramatically, necessitating scalable and accurate screening solutions. This paper presents a comprehensive study on deep learning architectures for the automated…

Computer Vision and Pattern Recognition · Computer Science 2025-12-12 Mohammad Sadegh Gholizadeh , Amir Arsalan Rezapour

Structural magnetic resonance imaging (sMRI) has shown great clinical value and has been widely used in deep learning (DL) based computer-aided brain disease diagnosis. Previous approaches focused on local shapes and textures in sMRI that…

Image and Video Processing · Electrical Eng. & Systems 2023-06-09 Gongshu Wang , Ning Jiang , Yunxiao Ma , Tiantian Liu , Duanduan Chen , Jinglong Wu , Guoqi Li , Dong Liang , Tianyi Yan

We study the problem of concept induction in visual reasoning, i.e., identifying concepts and their hierarchical relationships from question-answer pairs associated with images; and achieve an interpretable model via working on the induced…

Computer Vision and Pattern Recognition · Computer Science 2021-08-25 Zhonghao Wang , Kai Wang , Mo Yu , Jinjun Xiong , Wen-mei Hwu , Mark Hasegawa-Johnson , Humphrey Shi

The in vivo observation of the human retina at the cellular level is crucial to detect lesions before irreversible visual loss occurs, to follow the time course of retinal diseases and to evaluate and monitor the early effects of…

Vision-Language Models (VLMs) offer a promising path toward interpretable medical diagnosis by allowing users to ask about clinical explanations alongside predictions and across different modalities. However, training VLMs for detailed…

Computer Vision and Pattern Recognition · Computer Science 2025-12-15 Chenjun Li , Cheng Wan , Laurin Lux , Alexander Berger , Richard B. Rosen , Martin J. Menten , Johannes C. Paetzold

The evaluation and monitoring of cells health in the human retina is crucial and follow time course of retinal diseases, detect lesions before irreversible visual loss and to evaluate treatment effects. Towards this goal, a major challenge…

Skin cancer is a serious worldwide health issue, precise and early detection is essential for better patient outcomes and effective treatment. In this research, we use modern deep learning methods and explainable artificial intelligence…

Image and Video Processing · Electrical Eng. & Systems 2023-12-19 Faysal Mahmud , Md. Mahin Mahfiz , Md. Zobayer Ibna Kabir , Yusha Abdullah

Optical Coherence Tomography (OCT) is one of the most important retinal imaging technique. However, involuntary motion artifacts still pose a major challenge in OCT imaging that compromises the quality of downstream analysis, such as…

Image and Video Processing · Electrical Eng. & Systems 2023-05-31 Yiqian Wang , Alexandra Warter , Melina Cavichini , Varsha Alex , Dirk-Uwe G. Bartsch , William R. Freeman , Truong Q. Nguyen , Cheolhong An

Ophthalmic images and derivatives such as the retinal nerve fiber layer (RNFL) thickness map are crucial for detecting and monitoring ophthalmic diseases (e.g., glaucoma). For computer-aided diagnosis of eye diseases, the key technique is…

Precise spatial modeling in the operating room (OR) is foundational to many clinical tasks, supporting intraoperative awareness, hazard avoidance, and surgical decision-making. While existing approaches leverage large-scale multimodal…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Peiqi He , Zhenhao Zhang , Yixiang Zhang , Xiongjun Zhao , Shaoliang Peng

Retinal optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA) are promising tools for the (early) diagnosis of Alzheimer's disease (AD). These non-invasive imaging techniques are cost-effective and more…

Image and Video Processing · Electrical Eng. & Systems 2022-09-09 Yasemin Turkan , F. Boray Tek

Histopathological analysis is crucial in artery characterization for coronary artery disease (CAD). However, histology requires an invasive and time-consuming process. In this paper, we propose to generate virtual histology staining using…

Image and Video Processing · Electrical Eng. & Systems 2022-11-15 Xueshen Li , Hongshan Liu , Xiaoyu Song , Brigitta C. Brott , Silvio H. Litovsky , Yu Gan