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Inpainting shadowed regions cast by superficial blood vessels in retinal optical coherence tomography (OCT) images is critical for accurate and robust machine analysis and clinical diagnosis. Traditional sequence-based approaches such as…

Computer Vision and Pattern Recognition · Computer Science 2022-02-24 Yaoqi Tang , Yufan Li , Hongshan Liu , Jiaxuan Li , Peiyao Jin , Yu Gan , Yuye Ling , Yikai Su

Accurate staging of Diabetic Retinopathy (DR) is essential for guiding timely interventions and preventing vision loss. However, current staging models are hardly interpretable, and most public datasets contain no clinical reasoning or…

Computer Vision and Pattern Recognition · Computer Science 2025-09-19 Chenjun Li , Laurin Lux , Alexander H. Berger , Martin J. Menten , Mert R. Sabuncu , Johannes C. Paetzold

Optical Coherence Tomography (OCT) is the primary imaging modality for detecting pathological biomarkers associated to retinal diseases such as Age-Related Macular Degeneration. In practice, clinical diagnosis and treatment strategies are…

Computer Vision and Pattern Recognition · Computer Science 2019-07-17 Thomas Kurmann , Pablo Márquez-Neila , Siqing Yu , Marion Munk , Sebastian Wolf , Raphael Sznitman

Existing open set recognition (OSR) methods are typically designed for static scenarios, where models aim to classify known classes and identify unknown ones within fixed scopes. This deviates from the expectation that the model should…

Computer Vision and Pattern Recognition · Computer Science 2025-09-10 Runqing Yang , Yimin Fu , Changyuan Wu , Zhunga Liu

Black-box deep learning approaches have showcased significant potential in the realm of medical image analysis. However, the stringent trustworthiness requirements intrinsic to the medical field have catalyzed research into the utilization…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Yequan Bie , Luyang Luo , Hao Chen

Optical Chemical Structure Recognition (OCSR) plays a pivotal role in modern chemical informatics, enabling the automated conversion of chemical structure images from scientific literature, patents, and educational materials into…

Computer Vision and Pattern Recognition · Computer Science 2025-11-24 Wenrui Zhang , Xinggang Wang , Bin Feng , Wenyu Liu

Medical image segmentation is a difficult but important task for many clinical operations such as cardiac bi-ventricular volume estimation. More recently, there has been a shift to utilizing deep learning and fully convolutional neural…

Image and Video Processing · Electrical Eng. & Systems 2020-03-17 Jesse Sun , Fatemeh Darbehani , Mark Zaidi , Bo Wang

Synthetic Aperture Radar (SAR) provides robust all-weather imaging capabilities; however, translating SAR observations into photo-realistic optical images remains a fundamentally ill-posed problem. Current approaches are often hindered by…

Computer Vision and Pattern Recognition · Computer Science 2026-01-13 Hyunseo Lee , Sang Min Kim , Ho Kyung Shin , Taeheon Kim , Woo-Jeoung Nam

How well are unimodal vision and language models aligned? Although prior work have approached answering this question, their assessment methods do not directly translate to how these models are used in practical vision-language tasks. In…

Computer Vision and Pattern Recognition · Computer Science 2025-04-22 Le Zhang , Qian Yang , Aishwarya Agrawal

Distal myopathy represents a genetically heterogeneous group of skeletal muscle disorders with broad clinical manifestations, posing diagnostic challenges in radiology. To address this, we propose a novel multimodal attention-aware fusion…

Purpose: We proposed a deep convolutional neural network (CNN), named Retinal Fluid Segmentation Network (ReF-Net) to segment volumetric retinal fluid on optical coherence tomography (OCT) volume. Methods: 3 x 3-mm OCT scans were acquired…

Image and Video Processing · Electrical Eng. & Systems 2020-10-28 Yukun Guo , Tristan T. Hormel , Honglian Xiong , Jie Wang , Thomas S. Hwang , Yali Jia

This work explores the effectiveness of masked image modelling for learning representations of retinal OCT images. To this end, we leverage Masked Autoencoders (MAE), a simple and scalable method for self-supervised learning, to obtain a…

Computer Vision and Pattern Recognition · Computer Science 2024-05-24 Theodoros Pissas , Pablo Márquez-Neila , Sebastian Wolf , Martin Zinkernagel , Raphael Sznitman

Retinal imaging provides a non-invasive window into systemic microvascular health and has emerged as a potential biomarker for systemic diseases. However, whether retinal features encode biologically meaningful systemic signals that can be…

Image and Video Processing · Electrical Eng. & Systems 2026-05-26 Mini Han Wang , Liting Huang , Wei Hong , Boonthawan Wingwon

Vision-language models (VLMs) have shown strong promise for medical image analysis, but most remain opaque, offering predictions without the transparent, stepwise reasoning clinicians rely on. We present a framework that brings…

Computer Vision and Pattern Recognition · Computer Science 2025-10-31 Andriy Myronenko , Dong Yang , Baris Turkbey , Mariam Aboian , Sena Azamat , Esra Akcicek , Hongxu Yin , Pavlo Molchanov , Marc Edgar , Yufan He , Pengfei Guo , Yucheng Tang , Daguang Xu

Optical coherence tomography (OCT) is a volumetric imaging modality that empowers clinicians and scientists to noninvasively visualize the cross-sections of biological samples. As the latest generation of its kind, Fourier-domain OCT…

Image and Video Processing · Electrical Eng. & Systems 2020-05-20 Yuye Ling , Mengyuan Wang , Yu Gan , Xinwen Yao , Leopold Schmetterer , Chuanqing Zhou , Yikai Su

The treatment of age-related macular degeneration (AMD) requires continuous eye exams using optical coherence tomography (OCT). The need for treatment is determined by the presence or change of disease-specific OCT-based biomarkers.…

Image and Video Processing · Electrical Eng. & Systems 2026-03-12 Timo Kepp , Helge Sudkamp , Claus von der Burchard , Hendrik Schenke , Peter Koch , Gereon Hüttmann , Johann Roider , Mattias P. Heinrich , Heinz Handels

Deep neural networks for medical image classification often fail to generalize consistently in clinical practice due to violations of the i.i.d. assumption and opaque decision-making. This paper examines interpretability in deep neural…

Computer Vision and Pattern Recognition · Computer Science 2025-04-09 Mohammad Hossein Najafi , Mohammad Morsali , Mohammadreza Pashanejad , Saman Soleimani Roudi , Mohammad Norouzi , Saeed Bagheri Shouraki

Surgery is the only viable treatment for cataract patients with visual acuity (VA) impairment. Clinically, to assess the necessity of cataract surgery, accurately predicting postoperative VA before surgery by analyzing multi-view optical…

Image and Video Processing · Electrical Eng. & Systems 2022-12-13 Jinhong Wang , Jingwen Wang , Tingting Chen , Wenhao Zheng , Zhe Xu , Xingdi Wu , Wen Xu , Haochao Ying , Danny Chen , Jian Wu

Purpose: Disease progression of retinal atrophy associated with AMD requires the accurate quantification of the retinal atrophy changes on longitudinal OCT studies. It is based on finding, comparing, and delineating subtle atrophy changes…

Image and Video Processing · Electrical Eng. & Systems 2023-08-01 Adi Szeskin , Roei Yehuda , Or Shmueli , Jaime Levy , Leo Joskowicz

Multiple-surface segmentation in Optical Coherence Tomography (OCT) images is a challenge problem, further complicated by the frequent presence of weak image boundaries. Recently, many deep learning (DL) based methods have been developed…

Image and Video Processing · Electrical Eng. & Systems 2022-10-13 Hui Xie , Weiyu Xu , Xiaodong Wu