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This study explores the deployment of three machine learning (ML) approaches for real-time prediction of glucose, lactate, and ammonium concentrations in cell culture processes, using Raman spectroscopy as input features. The research…

Quantitative Methods · Quantitative Biology 2025-09-04 Thanh Tung Khuat , Johnny Peng , Robert Bassett , Ellen Otte , Bogdan Gabrys

Digital hematopathology requires cell-level analysis across diverse disease categories, including malignant disorders (e.g., leukemia), infectious conditions (e.g., malaria), and non-malignant red blood cell disorders (e.g., sickle cell…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Abdul Rehman , Iqra Rasool , Ayisha Imran , Mohsen Ali , Waqas Sultani

Self-supervised Learning (SSL) has become a powerful paradigm for representation learning without manual annotations. However, most existing frameworks focus on global alignment and struggle to capture the hierarchical, multi-scale lesion…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Abdullah Al Mamun , Miaohua Zhang , David Ahmedt-Aristizabal , Zeeshan Hayder , Mohammad Awrangjeb

While Transformer language models (LMs) are state-of-the-art for information extraction, long text introduces computational challenges requiring suboptimal preprocessing steps or alternative model architectures. Sparse attention LMs can…

Computation and Language · Computer Science 2022-12-01 Joel Stremmel , Brian L. Hill , Jeffrey Hertzberg , Jaime Murillo , Llewelyn Allotey , Eran Halperin

Cancer drug response prediction (DRP) models present a promising approach towards precision oncology, tailoring treatments to individual patient profiles. While deep learning (DL) methods have shown great potential in this area, models that…

Quantitative structure-activity relationship (QSAR) modelling is effective 'bridge' to search the reliable relationship related bioactivity to molecular structure. A QSAR classification model contains a lager number of redundant, noisy and…

Machine Learning · Computer Science 2018-05-01 Liang-Yong Xia , Qing-Yong Wang

In this work, we have developed a multiscale computational algorithm to couple finite element method with an open source molecular dynamics code --- the Large scale Atomic/Molecular Massively Parallel Simulator (LAMMPS) --- to perform…

Soft Condensed Matter · Physics 2019-09-17 Takahiro Murashima , Shingo Urata , Shaofan Li

Quantum Machine Learning (QML) shows how it maintains certain significant advantages over machine learning methods. It now shows that hybrid quantum methods have great scope for deployment and optimisation, and hold promise for future…

Machine Learning · Computer Science 2023-01-03 Juan Kenyhy Hancco-Quispe , Jordan Piero Borda-Colque , Fred Torres-Cruz

In biological research machine learning algorithms are part of nearly every analytical process. They are used to identify new insights into biological phenomena, interpret data, provide molecular diagnosis for diseases and develop…

Survival analysis (SA) is an active field of research that is concerned with time-to-event outcomes and is prevalent in many domains, particularly biomedical applications. Despite its importance, SA remains challenging due to small-scale…

Machine Learning · Statistics 2022-02-16 Philipp Kopper , Simon Wiegrebe , Bernd Bischl , Andreas Bender , David Rügamer

The current landscape of scientific research is widely based on modeling and simulation, typically with complexity in the simulation's flow of execution and parameterization properties. Execution flows are not necessarily straightforward…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-07-26 Eduardo Ponce , Brittany Stephenson , Suzanne Lenhart , Judy Day , Gregory D. Peterson

The individual optimization of quantum circuit parameters is currently one of the main practical bottlenecks in variational quantum eigensolvers for electronic systems. To this end, several machine learning approaches have been proposed to…

Quantum Physics · Physics 2025-11-06 Davide Bincoletto , Korbinian Stein , Jonas Motyl , Jakob S. Kottmann

Laser-plasma based experiments are always more demanding about the plasma features which need to be generated during the interaction. This is valid for laser-plasma acceleration as well as for inertial confinement fusion experiments. Most…

Plasma Physics · Physics 2025-09-03 F. Filippi , M. Cipriani , S. Mastrostefano , M. Scisciò , F. Consoli

Determining the aqueous solubility of molecules is a vital step in many pharmaceutical, environmental, and energy storage applications. Despite efforts made over decades, there are still challenges associated with developing a solubility…

Materials Science · Physics 2022-09-05 Gihan Panapitiya , Michael Girard , Aaron Hollas , Vijay Murugesan , Wei Wang , Emily Saldanha

Uniform Manifold Approximation and Projection (UMAP) is a widely used manifold learning technique for dimensionality reduction. This paper studies UMAP, supervised UMAP, and several competing dimensionality reduction methods, including…

Machine Learning · Computer Science 2026-05-04 Guanzhe Zhang , Shanshan Ding , Zhezhen Jin

In recent years, with the significant evolution of multi-modal large models, many recommender researchers realized the potential of multi-modal information for user interest modeling. In industry, a wide-used modeling architecture is a…

Machine Learning (ML) has offered innovative perspectives for accelerating the discovery of new functional materials, leveraging the increasing availability of material databases. Despite the promising advances, data-driven methods face…

A parallel code has been written in FORTRAN90, C, and MPI for the analysis of biological simulation data. Using a master/slave algorithm, the software operates on AMBER generated trajectory data using either UNIX or MPI file IO, and it…

Computational Physics · Physics 2008-08-25 David N. Lebard

Molecular property prediction integrates quantum chemistry, cheminformatics, and deep learning to connect molecular structure with physicochemical and biological behavior. This survey traces four complementary paradigms, including Quantum,…

Molecular dynamics (MD) simulation is a powerful tool for studying biomolecular structural changes, molecular recognition, transmembrane transport, and functional mechanisms. However, its practical bottleneck lies not only in software…

Quantitative Methods · Quantitative Biology 2026-04-22 Zhenyu Ma , Chunyi Yang , Yuyang Song , Jingyi Zhu , Letian Yang , Limei Xu , Min Xiao , Xukai Jiang
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