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Quantum machine learning (QML) has great potential for the analysis of chemical datasets. However, conventional quantum data-encoding schemes, such as fingerprint encoding, are generally unfeasible for the accurate representation of…

Quantum Physics · Physics 2025-11-18 Choy Boy , Edoardo Altamura , Dilhan Manawadu , Ivano Tavernelli , Stefano Mensa , David J. Wales

There are many problems in physics, biology, and other natural sciences in which symbolic regression can provide valuable insights and discover new laws of nature. A widespread Deep Neural Networks do not provide interpretable solutions.…

Machine Learning · Computer Science 2023-01-18 Sergei Popov , Mikhail Lazarev , Vladislav Belavin , Denis Derkach , Andrey Ustyuzhanin

We develop a generalized 3D shape generation prior model, tailored for multiple 3D tasks including unconditional shape generation, point cloud completion, and cross-modality shape generation, etc. On one hand, to precisely capture local…

Computer Vision and Pattern Recognition · Computer Science 2023-03-21 Yuhan Li , Yishun Dou , Xuanhong Chen , Bingbing Ni , Yilin Sun , Yutian Liu , Fuzhen Wang

Generating realistic human grasps is a crucial yet challenging task for applications involving object manipulation in computer graphics and robotics. Existing methods often struggle with generating fine-grained realistic human grasps that…

Computer Vision and Pattern Recognition · Computer Science 2024-07-22 Zhe Zhao , Mengshi Qi , Huadong Ma

Molecule generation is to design new molecules with specific chemical properties and further to optimize the desired chemical properties. Following previous work, we encode molecules into continuous vectors in the latent space and then…

Machine Learning · Computer Science 2020-01-16 Chaochao Yan , Sheng Wang , Jinyu Yang , Tingyang Xu , Junzhou Huang

Generating high-quality Scalable Vector Graphics (SVGs) from text remains a significant challenge. Existing LLM-based models that generate SVG code as a flat token sequence struggle with poor structural understanding and error accumulation,…

Computer Vision and Pattern Recognition · Computer Science 2026-04-10 Ximing Xing , Juncheng Hu , Ziteng Xue , Jing Zhang , Buyu Li , Sheng Wang , Dong Xu , Qian Yu

The generation and preservation of complex quantum states against environmental noise are paramount challenges in advancing continuous-variable (CV) quantum information processing. This paper introduces a novel framework based on…

Quantum Physics · Physics 2025-06-25 Haitao Huang , Chuangtao Chen , Qinglin Zhao

Vector Quantized Variational Autoencoders (VQ-VAEs) are fundamental models that compress continuous visual data into discrete tokens. Existing methods have tried to improve the quantization strategy for better reconstruction quality,…

Computer Vision and Pattern Recognition · Computer Science 2025-07-15 Mingkai Jia , Wei Yin , Xiaotao Hu , Jiaxin Guo , Xiaoyang Guo , Qian Zhang , Xiao-Xiao Long , Ping Tan

Text-conditioned molecular generation aims to translate natural-language descriptions into chemical structures, enabling scientists to specify functional groups, scaffolds, and physicochemical constraints without handcrafted rules.…

Machine Learning · Computer Science 2025-11-18 Lingxiao Li , Haobo Zhang , Bin Chen , Jiayu Zhou

Generative recommendation frameworks typically represent items as discrete Semantic IDs (SIDs). While existing studies have sought to enhance SID construction by incorporating multimodal content, collaborative signals, or more advanced…

Information Retrieval · Computer Science 2026-04-30 Yibiao Wei , Jie Zou , Pengfei Zhang , Xiao Ao , Weikang Guo , Zeyu Ma , Yang Yang

Existing diffusion codecs typically build on text-to-image diffusion foundation models like Stable Diffusion. However, text conditioning is suboptimal from a compression perspective, hindering the potential of downstream diffusion codecs,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Zhaoyang Jia , Zihan Zheng , Naifu Xue , Jiahao Li , Bin Li , Zongyu Guo , Xiaoyi Zhang , Houqiang Li , Yan Lu

Diffusion-based methods represented as stochastic differential equations on a continuous-time domain have recently proven successful as a non-adversarial generative model. Training such models relies on denoising score matching, which can…

Machine Learning · Computer Science 2024-11-05 Sarthak Mittal , Korbinian Abstreiter , Stefan Bauer , Bernhard Schölkopf , Arash Mehrjou

Deep generative models have been praised for their ability to learn smooth latent representation of images, text, and audio, which can then be used to generate new, plausible data. However, current generative models are unable to work with…

Machine Learning · Computer Science 2019-09-09 Bidisha Samanta , Abir De , Gourhari Jana , Pratim Kumar Chattaraj , Niloy Ganguly , Manuel Gomez-Rodriguez

Can we train a 3D molecule generator using data from dense regions to generate samples in sparse regions? This challenge can be framed as an out-of-distribution (OOD) generation problem. While prior research on OOD generation predominantly…

Machine Learning · Computer Science 2026-03-03 Haokai Hong , Wanyu Lin , Ming Yang , Kay Chen Tan

3D molecule generation is crucial for drug discovery and material science, requiring models to process complex multi-modalities, including atom types, chemical bonds, and 3D coordinates. A key challenge is integrating these modalities of…

Machine Learning · Computer Science 2025-10-14 Yanchen Luo , Zhiyuan Liu , Yi Zhao , Sihang Li , Hengxing Cai , Kenji Kawaguchi , Tat-Seng Chua , Yang Zhang , Xiang Wang

Medical image segmentation using deep learning (DL) has enabled the development of automated analysis pipelines for large-scale population studies. However, state-of-the-art DL methods are prone to hallucinations, which can result in…

Image and Video Processing · Electrical Eng. & Systems 2026-03-31 Vincenzo Marcianò , Hava Chaptoukaev , Virginia Fernandez , M. Jorge Cardoso , Sébastien Ourselin , Michela Antonelli , Maria A. Zuluaga

In this work, we present FRIGID, a framework with a novel diffusion language model that generates molecular structures conditioned on mass spectra via intermediate fingerprint representations and determined chemical formulae, training at…

A well-known limitation of existing molecular generative models is that the generated molecules highly resemble those in the training set. To generate truly novel molecules that may have even better properties for de novo drug discovery,…

Biomolecules · Quantitative Biology 2023-06-06 Seul Lee , Jaehyeong Jo , Sung Ju Hwang

Uncovering emergent concepts across transformer layers remains a significant challenge because the residual stream linearly mixes and duplicates information, obscuring how features evolve within large language models. Current research…

Machine Learning · Computer Science 2025-07-18 Ankur Garg , Xuemin Yu , Hassan Sajjad , Samira Ebrahimi Kahou

Quantum computing has emerged as a promising platform for simulating strongly correlated systems in chemistry, for which the standard quantum chemistry methods are either qualitatively inaccurate or too expensive. However, due to the…

Chemical Physics · Physics 2024-05-06 Max Rossmannek , Fabijan Pavošević , Angel Rubio , Ivano Tavernelli