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In biomedical Subgroup Discovery, practitioners are interested in discovering interpretable and homogeneous subgroups within a group of patients. In this paper, assuming that healthy subjects (i.e., controls) share common but irrelevant…

Machine Learning · Computer Science 2026-05-21 Robin Louiset , Edouard Duchesnay , Benoit Dufumier , Antoine Grigis , Pietro Gori

Subgroup discovery is a local pattern mining technique to find interpretable descriptions of sub-populations that stand out on a given target variable. That is, these sub-populations are exceptional with regard to the global distribution.…

Databases · Computer Science 2017-09-26 Janis Kalofolias , Mario Boley , Jilles Vreeken

Deep neural two-sample tests have recently shown strong power for detecting distributional differences between groups, yet their black-box nature limits interpretability and practical adoption in biomedical analysis. Moreover, most existing…

Computer Vision and Pattern Recognition · Computer Science 2026-02-06 Masoumeh Javanbakhat , Piotr Komorowski , Dilyara Bareeva , Wei-Chang Lai , Wojciech Samek , Christoph Lippert

Selecting subsets of features that differentiate between two conditions is a key task in a broad range of scientific domains. In many applications, the features of interest form clusters with similar effects on the data at hand. To recover…

Machine Learning · Computer Science 2022-11-11 Ram Dyuthi Sristi , Gal Mishne , Ariel Jaffe

When analyzing the behavior of machine learning algorithms, it is important to identify specific data subgroups for which the considered algorithm shows different performance with respect to the entire dataset. The intervention of domain…

Machine Learning · Computer Science 2021-08-18 Eliana Pastor , Luca de Alfaro , Elena Baralis

During data analysis, we are often perplexed by certain disparities observed between two groups of interest within a dataset. To better understand an observed disparity, we need explanations that can pinpoint the data regions where the…

Databases · Computer Science 2025-12-10 Tal Blau , Brit Youngmann , Anna Fariha , Yuval Moskovitch

The performance of machine learning models relies heavily on the quality of input data, yet real-world applications often face significant data-related challenges. A common issue arises when curating training data or deploying models: two…

Machine Learning · Computer Science 2025-09-24 Varun Babbar , Zhicheng Guo , Cynthia Rudin

Understanding causal mechanisms across different populations is essential for designing effective public health interventions. Recently, difference graphs have been introduced as a tool to visually represent causal variations between two…

Artificial Intelligence · Computer Science 2025-02-18 Charles K. Assaad

Machine learning (ML) models may suffer from significant performance disparities between patient groups. Identifying such disparities by monitoring performance at a granular level is crucial for safely deploying ML to each patient.…

Machine Learning · Computer Science 2025-03-14 Alceu Bissoto , Trung-Dung Hoang , Tim Flühmann , Susu Sun , Christian F. Baumgartner , Lisa M. Koch

Divergent word usages reflect differences among people. In this paper, we present a novel angle for studying word usage divergence -- word interpretations. We propose an approach that quantifies semantic differences in interpretations among…

Computation and Language · Computer Science 2017-03-30 Tianran Hu , Ruihua Song , Maya Abtahian , Philip Ding , Xing Xie , Jiebo Luo

Scientific expertise often requires recognizing subtle visual differences that remain challenging to articulate even for domain experts. We present a system that leverages generative models to automatically discover and visualize minimal…

Computer Vision and Pattern Recognition · Computer Science 2025-05-16 Mia Chiquier , Orr Avrech , Yossi Gandelsman , Berthy Feng , Katherine Bouman , Carl Vondrick

We investigate performance disparities in deep classifiers. We find that the ability of classifiers to separate individuals into subgroups varies substantially across medical imaging modalities and protected characteristics; crucially, we…

Computer Vision and Pattern Recognition · Computer Science 2023-07-07 Charles Jones , Mélanie Roschewitz , Ben Glocker

In a given classification task, the accuracy of the learner is often hampered by finiteness of the training set, high-dimensionality of the feature space and severe overlap between classes. In the context of interpretable learners, with…

Machine Learning · Computer Science 2025-04-03 Marco Canducci , Lida Abdi , Alessandro Prete , Roland J. Veen , Michael Biehl , Wiebke Arlt , Peter Tino

This paper deals with the derivation of a collective model of cell populations out of an individual-based description of the underlying physical particle system. By looking at the spatial distribution of cells in terms of time-evolving…

Mathematical Physics · Physics 2014-11-12 Annachiara Colombi , Marco Scianna , Andrea Tosin

Medical studies frequently require to extract the relationship between each covariate and the outcome with statistical confidence measures. To do this, simple parametric models are frequently used (e.g. coefficients of linear regression)…

Machine Learning · Computer Science 2023-05-02 Zachary Izzo , Ruishan Liu , James Zou

Analyzing the behaviour of a population in response to disease and interventions is critical to unearth variability in healthcare as well as understand sub-populations that require specialized attention, but also to assist in designing…

Machine Learning · Computer Science 2021-11-30 Isaiah Onando Mulang' , William Ogallo , Girmaw Abebe Tadesse , Aisha Walcott-Bryant

We study two-sample variable selection: identifying variables that discriminate between the distributions of two sets of data vectors. Such variables help scientists understand the mechanisms behind dataset discrepancies. Although…

Machine Learning · Statistics 2025-11-06 Kensuke Mitsuzawa , Motonobu Kanagawa , Stefano Bortoli , Margherita Grossi , Paolo Papotti

Discovering patterns in data that best describe the differences between classes allows to hypothesize and reason about class-specific mechanisms. In molecular biology, for example, this bears promise of advancing the understanding of…

Machine Learning · Computer Science 2023-12-08 Nils Philipp Walter , Jonas Fischer , Jilles Vreeken

Deriving insights from high-dimensional data is one of the core problems in data mining. The difficulty mainly stems from the fact that there are exponentially many variable combinations to potentially consider, and there are infinitely…

Machine Learning · Statistics 2021-11-08 Jefrey Lijffijt , Bo Kang , Wouter Duivesteijn , Kai Puolamäki , Emilia Oikarinen , Tijl De Bie

In recent years, deep learning models have been extensively applied to biological data across various modalities. Discriminative deep learning models have excelled at classifying images into categories (e.g., healthy versus diseased,…

Computer Vision and Pattern Recognition · Computer Science 2025-02-17 Anis Bourou , Saranga Kingkor Mahanta , Thomas Boyer , Valérie Mezger , Auguste Genovesio
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