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The dearth of prescribing guidelines for physicians is one key driver of the current opioid epidemic in the United States. In this work, we analyze medical and pharmaceutical claims data to draw insights on characteristics of patients who…

Machine Learning · Computer Science 2020-05-01 Chirag Nagpal , Dennis Wei , Bhanukiran Vinzamuri , Monica Shekhar , Sara E. Berger , Subhro Das , Kush R. Varshney

This paper introduces Redescription Model Mining, a novel approach to identify interpretable patterns across two datasets that share only a subset of attributes and have no common instances. In particular, Redescription Model Mining aims to…

Databases · Computer Science 2021-07-12 Felix I. Stamm , Martin Becker , Markus Strohmaier , Florian Lemmerich

For measuring the strength of visually-observed subpopulation differences, the Population Difference Criterion is proposed to assess the statistical significance of visually observed subpopulation differences. It addresses the following…

Methodology · Statistics 2023-09-21 Xi Yang , Jan Hannig , Katherine A. Hoadley , Iain Carmichael , J. S. Marron

Multiplex networks have emerged as a promising approach for modeling complex systems, where each layer represents a different mode of interaction among entities of the same type. A core task in analyzing these networks is to identify the…

Social and Information Networks · Computer Science 2024-11-11 Meiby Ortiz-Bouza , Selin Aviyente

Realizing sufficient separability between the distributions of healthy and pathological samples is a critical obstacle for pathology detection convolutional models. Moreover, these models exhibit a bias for contrast-based images, with…

Image and Video Processing · Electrical Eng. & Systems 2024-07-26 P. Bilha Githinji , Xi Yuan , Zhenglin Chen , Ijaz Gul , Dingqi Shang , Wen Liang , Jianming Deng , Dan Zeng , Dongmei yu , Chenggang Yan , Peiwu Qin

In many applications, it is important to identify subpopulations that survive longer or shorter than the rest of the population. In medicine, for example, it allows determining which patients benefit from treatment, and in predictive…

Machine Learning · Computer Science 2026-02-26 Mhd Jawad Al Rahwanji , Sascha Xu , Nils Philipp Walter , Jilles Vreeken

Personalized decision making targets the behavior of a specific individual, while population-based decision making concerns a sub-population resembling that individual. This paper clarifies the distinction between the two and explains why…

Artificial Intelligence · Computer Science 2022-08-23 Scott Mueller , Judea Pearl

Weakly supervised medical image segmentation (MIS) using generative models is crucial for clinical diagnosis. However, the accuracy of the segmentation results is often limited by insufficient supervision and the complex nature of medical…

Computer Vision and Pattern Recognition · Computer Science 2024-04-26 Zhihao Shuai , Yinan Chen , Shunqiang Mao , Yihan Zho , Xiaohong Zhang

We consider high-dimensional regression over subgroups of observations. Our work is motivated by biomedical problems, where disease subtypes, for example, may differ with respect to underlying regression models, but sample sizes at the…

Learning a parametric model from a given dataset indeed enables to capture intrinsic dependencies between random variables via a parametric conditional probability distribution and in turn predict the value of a label variable given…

Machine Learning · Statistics 2024-06-14 Elouan Argouarc'h , François Desbouvries , Eric Barat , Eiji Kawasaki

We developed a tool for detecting domain shifts, namely subtle differences in the probability distributions of datasets. We identify these shifts using an algorithm designed to detect localised density anomalies in high-dimensional feature…

Machine Learning · Statistics 2026-05-18 Sebastian Springer , Alessandro Laio

Analyzing data subgroups is a common data science task to build intuition about a dataset and identify areas to improve model performance. However, subgroup analysis is prohibitively difficult in datasets with many features, and existing…

Human-Computer Interaction · Computer Science 2025-02-18 Venkatesh Sivaraman , Zexuan Li , Adam Perer

The most popular face recognition benchmarks assume a distribution of subjects without much attention to their demographic attributes. In this work, we perform a comprehensive discrimination-aware experimentation of deep learning-based face…

Computer Vision and Pattern Recognition · Computer Science 2020-04-07 Ignacio Serna , Aythami Morales , Julian Fierrez , Manuel Cebrian , Nick Obradovich , Iyad Rahwan

Machine learning models often perform poorly on subgroups that are underrepresented in the training data. Yet, little is understood on the variation in mechanisms that cause subpopulation shifts, and how algorithms generalize across such…

Machine Learning · Computer Science 2023-08-21 Yuzhe Yang , Haoran Zhang , Dina Katabi , Marzyeh Ghassemi

We consider the problem in regression analysis of identifying subpopulations that exhibit different patterns of response, where each subpopulation requires a different underlying model. Unlike statistical cohorts, these subpopulations are…

Machine Learning · Statistics 2018-10-25 Alexander New , Curt Breneman , Kristin P. Bennett

The paradigm shift toward structure-driven molecule generation has been propelled by advances in deep generative models, such as variational auto-encoders and diffusion models. However, these generative models for molecular design remain…

Machine Learning · Computer Science 2026-04-17 Peidong Liu , Wenbo Zhang , Wei Ju , Jiancheng Lv , Xianggen Liu

Targeting to understand the underlying explainable factors behind observations and modeling the conditional generation process on these factors, we connect disentangled representation learning to Diffusion Probabilistic Models (DPMs) to…

Computer Vision and Pattern Recognition · Computer Science 2023-10-31 Tao Yang , Yuwang Wang , Yan Lv , Nanning Zheng

The aim in many sciences is to understand the mechanisms that underlie the observed distribution of variables, starting from a set of initial hypotheses. Causal discovery allows us to infer mechanisms as sets of cause and effect…

Machine Learning · Computer Science 2025-03-05 Ashka Shah , Adela DePavia , Nathaniel Hudson , Ian Foster , Rick Stevens

In machine learning, disparity metrics are often defined by measuring the difference in the performance or outcome of a model, across different sub-populations (groups) of datapoints. Thus, the inputs to disparity quantification consist of…

Computer Vision and Pattern Recognition · Computer Science 2022-04-15 Shervin Ardeshir , Cristina Segalin , Nathan Kallus

Suppose it is of interest to characterize effect heterogeneity of an intervention across levels of a baseline covariate using only pre- and post- intervention outcome measurements from those who received the intervention, i.e. with no…

Methodology · Statistics 2023-06-21 Zach Shahn