English
Related papers

Related papers: Benchmarking virtual cell models for in-the-wild p…

200 papers

Cellular Agent-Based Models are commonly employed to describe a variety biological systems. Over the course of the past years, many modeling tools have emerged which solve particular research questions. In this short opinion piece, we argue…

Cell Behavior · Quantitative Biology 2025-11-18 Jonas Pleyer

Document Visual Question Answering (VQA) models have evolved at an impressive rate over the past few years, coming close to or matching human performance on some benchmarks. We argue that common evaluation metrics used by popular benchmarks…

Computation and Language · Computer Science 2025-03-26 Armineh Nourbakhsh , Siddharth Parekh , Pranav Shetty , Zhao Jin , Sameena Shah , Carolyn Rose

Vision-Language Models (VLMs) are powerful yet computationally intensive for widespread practical deployments. To address such challenge without costly re-training, post-training acceleration techniques like quantization and token reduction…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Yizheng Sun , Hao Li , Chang Xu , Hongpeng Zhou , Chenghua Lin , Riza Batista-Navarro , Jingyuan Sun

Visual question answering (VQA) models respond to open-ended natural language questions about images. While VQA is an increasingly popular area of research, it is unclear to what extent current VQA architectures learn key semantic…

Computer Vision and Pattern Recognition · Computer Science 2018-07-25 Gabriel Grand , Aron Szanto , Yoon Kim , Alexander Rush

The fundamental understanding of how cells physically interact with each other and their environment is key to understanding their organisation in living tissues. Over the past decades several computational methods have been developed to…

Quantitative Methods · Quantitative Biology 2026-01-22 Paul Van Liedekerke , Jiří Pešek , Kevin Alessandri , Dirk Drasdo

Clinical reasoning in medicine is a hypothesis-driven process where physicians refine diagnoses from limited information through targeted history, physical examination, and diagnostic investigations. In contrast, current medical benchmarks…

Machine Learning · Computer Science 2025-10-14 Christopher Chiu , Silviu Pitis , Mihaela van der Schaar

Accurate predictions and representations of plant growth patterns in simulated and controlled environments are important for addressing various challenges in plant phenomics research. This review explores various works on state-of-the-art…

Quantitative Methods · Quantitative Biology 2025-07-17 Mohamed Debbagh , Shangpeng Sun , Mark Lefsrud

5G is being designed as a common platform where multiple vertical applications will be able to co-exist and grow in a seamless manner. The diversity of the vertical requirements as well as the particular features of the 5G network itself,…

Signal Processing · Electrical Eng. & Systems 2020-02-19 Orestes Manzanilla-Salazar , Victor Boutin , Hakim Mellah , Constant Wetté , Brunilde Sansò

Complex phenomena in engineering and the sciences are often modeled with computationally intensive feed-forward simulations for which a tractable analytic likelihood does not exist. In these cases, it is sometimes necessary to estimate an…

Methodology · Statistics 2020-06-18 Niccolò Dalmasso , Ann B. Lee , Rafael Izbicki , Taylor Pospisil , Ilmun Kim , Chieh-An Lin

De novo design seeks to generate molecules with required property profiles by virtual design-make-test cycles. With the emergence of deep learning and neural generative models in many application areas, models for molecular design based on…

Quantitative Methods · Quantitative Biology 2021-01-05 Nathan Brown , Marco Fiscato , Marwin H. S. Segler , Alain C. Vaucher

In the software development process, model transformation is increasingly assimilated. However, systems being developed with model transformation sometimes grow in size and become complex. Meanwhile, the performance of model transformation…

Software Engineering · Computer Science 2020-04-21 Vijayshree Vijayshree , Markus Frank , Steffen Becker

Visual language models (VLMs) have the potential to transform medical workflows. However, the deployment is limited by sycophancy. Despite this serious threat to patient safety, a systematic benchmark remains lacking. This paper addresses…

Computer Vision and Pattern Recognition · Computer Science 2026-05-29 Juangui Xu , Zikun Guo , Jingwei Lv , Hongbin Lin , Shu Yang , Jun Wen , Di Wang , Lijie Hu

What determines whether an organism or collective will survive under particular conditions? This question is asked across the life sciences when determining adaptive fit, developing efficacious treatments for diseases, and assessing the…

Quantitative Methods · Quantitative Biology 2026-05-19 Connor McShaffrey , Randall D. Beer

We investigate the ability of individuals to visually validate statistical models in terms of their fit to the data. While visual model estimation has been studied extensively, visual model validation remains under-investigated. It is…

Computer Vision and Pattern Recognition · Computer Science 2024-01-03 Daniel Braun , Ashley Suh , Remco Chang , Michael Gleicher , Tatiana von Landesberger

Motivated by critical challenges and needs from biopharmaceuticals manufacturing, we propose a general metamodel-assisted stochastic simulation uncertainty analysis framework to accelerate the development of a simulation model with modular…

Methodology · Statistics 2022-09-07 Wei Xie , Russell R. Barton , Barry L. Nelson , Keqi Wang

Deep learning models are widely used across computer vision and other domains. When working on the model induction, selecting the right architecture for a given dataset often relies on repetitive trial-and-error procedures. This procedure…

Machine Learning · Computer Science 2026-01-06 Yen-Chia Chen , Hsing-Kuo Pao , Hanjuan Huang

The classification of microscopy videos capturing complex cellular behaviors is crucial for understanding and quantifying the dynamics of biological processes over time. However, it remains a frontier in computer vision, requiring…

As computer vision and NLP make progress, Vision-Language(VL) is becoming an important area of research. Despite the importance, evaluation metrics of the research domain is still at a preliminary stage of development. In this paper, we…

Computer Vision and Pattern Recognition · Computer Science 2022-07-25 Sangmyeong Woh , Jaemin Lee , Ho Joong Kim , Jinsuk Lee

Simulators are a critical component of modern robotics research. Strategies for both perception and decision making can be studied in simulation first before deployed to real world systems, saving on time and costs. Despite significant…

Machine Learning · Computer Science 2020-11-19 Bhairav Mehta , Ankur Handa , Dieter Fox , Fabio Ramos

Optimization-based models have been used to predict cellular behavior for over 25 years. The constraints in these models are derived from genome annotations, measured macro-molecular composition of cells, and by measuring the cell's growth…

Quantitative Methods · Quantitative Biology 2019-05-21 Laurence Yang , Michael A. Saunders , Jean-Christophe Lachance , Bernhard O. Palsson , José Bento