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By focusing on melancholic features with biological homogeneity, this study aimed to identify a small number of critical functional connections (FCs) that were specific only to the melancholic type of MDD. On the resting-state fMRI data,…

Volume change measures derived from longitudinal MRI (e.g. hippocampal atrophy) are a well-studied biomarker of disease progression in Alzheimer's Disease (AD) and are used in clinical trials to track the therapeutic efficacy of…

Depression is a global health concern with a critical need for increased patient screening. Speech technology offers advantages for remote screening but must perform robustly across patients. We have described two deep learning models…

Audio and Speech Processing · Electrical Eng. & Systems 2024-12-30 Y. Lu , A. Harati , T. Rutowski , R. Oliveira , P. Chlebek , E. Shriberg

Objective: This study aimed to evaluate which voice features can predict health deterioration in patients with chronic HF. Background: Heart failure (HF) is a chronic condition with progressive deterioration and acute decompensations, often…

Invasive electroencephalograph (EEG) recordings of ten patients suffering from focal epilepsy were analyzed using the method of renormalized entropy. Introduced as a complexity measure for the different regimes of a dynamical system, the…

Medical Physics · Physics 2009-10-31 K. Kopitzki , P. C. Warnke , J. Timmer

This study proposes an innovative multimodal fusion model based on a teacher-student architecture to enhance the accuracy of depression classification. Our designed model addresses the limitations of traditional methods in feature fusion…

Computation and Language · Computer Science 2025-02-03 Lindy Gan , Yifan Huang , Xiaoyang Gao , Jiaming Tan , Fujun Zhao , Tao Yang

Deep learning systems often struggle with processing long sequences, where computational complexity can become a bottleneck. Current methods for automated dementia detection using speech frequently rely on static, time-agnostic features or…

Sound · Computer Science 2025-10-02 Chukwuemeka Ugwu , Oluwafemi Oyeleke

The theoretical basis of neuronal coding, associated with short term degradation in synaptic transmission, is a matter of debate in the literature. In fact, electrophysiological signals are commonly characterized as inversely proportional…

Neurons and Cognition · Quantitative Biology 2017-11-21 A. J. da Silva , S. Floquet , D. O. C. Santos

Characterizing the brain dynamics during different cortical states can reveal valuable information about its patterns across various cognitive processes. In particular, studying the differences between awake and sleep stages can shed light…

An effective way to scale up test-time compute of large language models is to sample multiple responses and then select the best one, as in Grok Heavy and Gemini Deep Think. Existing selection methods often rely on external reward models,…

Machine Learning · Computer Science 2026-05-04 Wenshuo Zhao , Qi Zhu , Xingshan Zeng , Fei Mi , Lifeng Shang , Yi R. , Fung

Electroencephalogram (EEG) is one of the most reliable physiological signal for emotion detection. Being non-stationary in nature, EEGs are better analysed by spectro temporal representations. Standard features like Discrete Wavelet…

Signal Processing · Electrical Eng. & Systems 2022-02-08 Upasana Tiwari , Rupayan Chakraborty , Sunil Kumar Kopparapu

Identifying and utilising various biomarkers for tracking Alzheimer's disease (AD) progression have received many recent attentions and enable helping clinicians make the prompt decisions. Traditional progression models focus on extracting…

Machine Learning · Computer Science 2023-11-08 Xulong Wang , Yu Zhang , Menghui Zhou , Tong Liu , Jun Qi , Po Yang

Deep neural networks have recently achieved competitive accuracy for human activity recognition. However, there is room for improvement, especially in modeling long-term temporal importance and determining the activity relevance of…

Computer Vision and Pattern Recognition · Computer Science 2018-08-23 Sibo Song , Ngai-Man Cheung , Vijay Chandrasekhar , Bappaditya Mandal

In behavioral health informatics, inferring an individual's psychological state from physiological and behavioral data is fundamental. A key physiological signal in this endeavor is electrodermal activity (EDA), often quantified as skin…

Systems and Control · Electrical Eng. & Systems 2023-11-07 Hui Sophie Wang , Stacy Marsella , Misha Pavel

Advances in wearable computing and AI have increased interest in leveraging PPG for health monitoring over the past decade. One of the biggest challenges in developing health algorithms based on such biosignals is the sparsity of clinical…

Large language model safety is usually assessed with static benchmarks, but key failures are dynamic: value drift under distribution shift, jailbreak attacks, and slow degradation of alignment in deployment. Building on a recent Second Law…

Computation and Language · Computer Science 2025-12-04 Samih Fadli

Depression, as a typical mental disorder, has become a prevalent issue significantly impacting public health. However, the prevention and treatment of depression still face multiple challenges, including complex diagnostic procedures,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Yu Luo , Nan Huang , Sophie Yu , Hendry Xu , Jerry Wang , Colin Wang , Zhichao Liu , Chen Zeng

Depression detection from speech has attracted a lot of attention in recent years. However, the significance of speaker-specific information in depression detection has not yet been explored. In this work, we analyze the significance of…

Computers and Society · Computer Science 2021-07-30 Sri Harsha Dumpala , Sebastian Rodriguez , Sheri Rempel , Rudolf Uher , Sageev Oore

Telehealth is a valuable tool for primary health care (PHC), where depression is a common condition. PHC is the first point of contact for most people with depression, but about 25% of diagnoses made by PHC physicians are inaccurate. Many…

Depression is a major mental health disorder that is rapidly affecting lives worldwide. Depression not only impacts emotional but also physical and psychological state of the person. Its symptoms include lack of interest in daily…

Computer Vision and Pattern Recognition · Computer Science 2017-09-19 Shubham Dham , Anirudh Sharma , Abhinav Dhall