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Biological active matter is typically tightly coupled to chemical reaction networks affecting its assembly-disassembly dynamics and stress generation. We show that localized states can emerge spontaneously if assembly of active matter is…

Biological Physics · Physics 2023-12-15 Luca Barberi , Karsten Kruse

We study motility-induced phase separation~(MIPS) in active AB binary mixtures undergoing the chemical reaction $A \rightleftharpoons B$. Starting from the evolution equations for the density fields $\rho_i(\vec r, t)$ describing MIPS, we…

Soft Condensed Matter · Physics 2025-05-05 Sayantan Mondal , Prasenjit Das

Phase-separated liquid condensates can spatially organize and thereby regulate chemical processes. However, the physicochemical mechanisms underlying such regulation remain elusive as the intramolecular interactions responsible for phase…

Soft Condensed Matter · Physics 2024-03-11 Sudarshana Laha , Jonathan Bauermann , Frank Jülicher , Thomas C. T. Michaels , Christoph A. Weber

The structure of Lyapunov spectra for many particle systems with a random interaction between the particles is discussed. The dynamics of the tangent space is expressed as a master equation, which leads to a formula that connects the…

Chaotic Dynamics · Physics 2007-05-23 Tooru Taniguchi , Gary P. Morriss

Complex biochemical pathways or regulatory enzyme kinetics can be reduced to chains of elementary reactions, which can be described in terms of chemical kinetics. This discipline provides a set of tools for quantifying and understanding the…

Quantitative Methods · Quantitative Biology 2018-01-08 Elena Agliari , Adriano Barra , Giulio Landolfi , Sara Murciano , Sarah Perrone

Phase separation in passive systems leads to uncontrolled droplet growth, limiting structural control in soft materials and cells. We identify a generic mechanism to arrest coarsening based on chemical interconversion between molecular…

Soft Condensed Matter · Physics 2026-03-19 Florian Raßhofer , Erwin Frey

Biomolecular condensates constitute a newly recognized form of spatial organization in living cells. Although many condensates are believed to form as a result of phase separation, the physicochemical properties that determine the phase…

Biological Physics · Physics 2023-07-11 William M. Jacobs

Chemical reactions that couple to systems that phase separate have been implicated in diverse contexts from biology to materials science. However, how a particular set of chemical reactions (chemical reaction network, CRN) would affect the…

Soft Condensed Matter · Physics 2024-04-25 Dino Osmanovic , Elisa Franco

An important question in the field of active matter is whether or not it is possible to predict the phase behavior of these systems. Here, we study the phase coexistence of binary mixtures of torque-free active Brownian particles, for both…

Soft Condensed Matter · Physics 2020-04-03 Berend van der Meer , Vasileios Prymidis , Marjolein Dijkstra , Laura Filion

Motility-induced phase separation, MIPS, is arguably the most well-studied collective phenomenon occurring in active matter without alignment interactions (scalar active matter). Its basic origin is simple: since self-propelled particles…

Soft Condensed Matter · Physics 2021-12-10 Joakim Stenhammar

Active colloids exhibit persistent motion, which can lead to motility-induced phase separation (MIPS). However, there currently exists no microscopic theory to account for this phenomenon. We report a first-principles theory, free of fit…

Soft Condensed Matter · Physics 2015-06-24 T. F. F. Farage , P. Krinninger , J. M. Brader

We introduce a model of chemically active particles of a multi-component fluid that can change their interactions with other particles depending on their state. Since such switching of interactions can only be maintained by the input of…

Soft Condensed Matter · Physics 2019-05-01 Dino Osmanovic , Yitzhak Rabin

Piecewise-Linear in Rates (PWLR) Lyapunov functions are introduced for a class of Chemical Reaction Networks (CRNs). In addition to their simple structure, these functions are robust with respect to arbitrary monotone reaction rates, of…

Optimization and Control · Mathematics 2016-09-09 M. Ali Al-Radhawi , David Angeli

We consider a mixture of one neutral and two oppositely charged types of molecules confined to a surface. Using analytical techniques and molecular dynamics simulations, we construct the phase diagram of the system and exhibit the…

Soft Condensed Matter · Physics 2009-11-11 Sharon M. Loverde , Francisco Solis , Monica Olvera de la Cruz

A model of interacting motile chaotic elements is proposed. The chaotic elements are distributed in space and interact with each other through interactions depending on their positions and their internal states. As the value of a governing…

Adaptation and Self-Organizing Systems · Physics 2009-11-07 Tatsuo Shibata , Kunihiko Kaneko

We present a thermodynamically consistent model describing the dynamics of a multi-component mixture where one enzyme component catalyzes a reaction between other components. We find that the catalytic activity alone can induce phase…

Biological Physics · Physics 2022-10-05 Matthew W. Cotton , Ramin Golestanian , Jaime Agudo-Canalejo

Many active biological particles, such as swimming microorganisms or motor-proteins, do work on their environment by going though a periodic sequence of shapes. Interactions between particles can lead to the phase-synchronization of their…

Soft Condensed Matter · Physics 2022-07-26 Brato Chakrabarti , Michael J. Shelley , Sebastian Fürthauer

These lecture notes describe a basic theory of chemically active droplets, which are droplets kept away from equilibrium by driven chemical reactions. The notes assume a basic familiarity with equilibrium thermodynamics of phase separation,…

Soft Condensed Matter · Physics 2024-07-16 David Zwicker

Active particles may undergo phase separation when interactions oppose self-propulsion, in the absence of any cohesive forces. The corresponding Motility-Induced Phase Separation (MIPS) is arguably the simplest non-trivial collective…

Soft Condensed Matter · Physics 2023-12-19 Jérémy O'Byrne , Alexandre Solon , Julien Tailleur , Yongfeng Zhao

Pair interactions between active particles need not follow Newton's third law. In this work we propose a continuum model of pattern formation due to non-reciprocal interaction between multiple species of scalar active matter. The classical…

Statistical Mechanics · Physics 2020-10-21 Suropriya Saha , Jaime Agudo-Canalejo , Ramin Golestanian