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Most machine learning (ML) models are developed for prediction only; offering no option for causal interpretation of their predictions or parameters/properties. This can hamper the health systems' ability to employ ML models in clinical…

Self-supervised learning in vision-language processing exploits semantic alignment between imaging and text modalities. Prior work in biomedical VLP has mostly relied on the alignment of single image and report pairs even though clinical…

Medical images usually suffer from image degradation in clinical practice, leading to decreased performance of deep learning-based models. To resolve this problem, most previous works have focused on filtering out degradation-causing…

Image and Video Processing · Electrical Eng. & Systems 2023-04-17 Haoxuan Che , Siyu Chen , Hao Chen

Contrastive Language-Image Pretraining (CLIP) models excel at understanding image-text relationships but struggle with adapting to new data without forgetting prior knowledge. To address this, models are typically fine-tuned using both new…

Machine Learning · Computer Science 2026-05-06 Ryan King , Gang Li , Bobak Mortazavi , Tianbao Yang

Cell-level dense prediction is central to computational pathology, but remains challenging due to fine-grained histological structures, strong domain shifts, and costly dense annotations. Existing ViT-based pathology foundation models rely…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Weiming Chen , Xitong Ling , Zhenyang Cai , Xidong Wang , Jiawen Li , Tian Guan , Benyou Wang , Yonghong He

Deep learning models have shown promising performance for cell nucleus segmentation in the field of pathology image analysis. However, training a robust model from multiple domains remains a great challenge for cell nucleus segmentation.…

Image and Video Processing · Electrical Eng. & Systems 2024-03-12 Dawei Fan , Yifan Gao , Jiaming Yu , Yanping Chen , Wencheng Li , Chuancong Lin , Kaibin Li , Changcai Yang , Riqing Chen , Lifang Wei

Clinical diagnosis begins with doctor-patient interaction, during which physicians iteratively gather information, determine examination and refine differential diagnosis through patients' response. This dynamic clinical-reasoning process…

Computation and Language · Computer Science 2025-12-30 Yuqi Tang , Jing Yu , Zichang Su , Kehua Feng , Zhihui Zhu , Libin Wang , Lei Liang , Qiang Zhang , Keyan Ding , Huajun Chen

Generating radiology reports automatically reduces the workload of radiologists and helps the diagnoses of specific diseases. Many existing methods take this task as modality transfer process. However, since the key information related to…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Yitian Tao , Liyan Ma , Jing Yu , Han Zhang

While large language models hold promise for complex medical applications, their development is hindered by the scarcity of high-quality reasoning data. To address this issue, existing approaches typically distill chain-of-thought reasoning…

Machine Learning · Computer Science 2026-04-14 Haolin Li , Shuyang Jiang , Ruipeng Zhang , Jiangchao Yao , Ya Zhang , Yanfeng Wang

Causal learning has long concerned itself with the accurate recovery of underlying causal mechanisms. Such causal modelling enables better explanations of out-of-distribution data. Prior works on causal learning assume that the high-level…

Pursuing training-free open-vocabulary semantic segmentation in an efficient and generalizable manner remains challenging due to the deep-seated spatial bias in CLIP. To overcome the limitations of existing solutions, this work moves beyond…

Computer Vision and Pattern Recognition · Computer Science 2026-05-14 Hao Zhu , Shuo Jin , Wenbin Liao , Jiayu Xiao , Yan Zhu , Siyue Yu , Feng Dai

Artificial intelligence in healthcare requires models that are accurate and interpretable. We advance mechanistic interpretability in medical vision by applying Medical Sparse Autoencoders (MedSAEs) to the latent space of MedCLIP, a…

Artificial Intelligence · Computer Science 2026-05-25 Riccardo Renzulli , Colas Lepoutre , Enrico Cassano , Marco Grangetto

Learning medical visual representations directly from paired images and reports through multimodal self-supervised learning has emerged as a novel and efficient approach to digital diagnosis in recent years. However, existing models suffer…

Computer Vision and Pattern Recognition · Computer Science 2025-06-16 Libin Lan , Hongxing Li , Zunhui Xia , Juan Zhou , Xiaofei Zhu , Yongmei Li , Yudong Zhang , Xin Luo

True intelligence hinges on the ability to uncover and leverage hidden causal relations. Despite significant progress in AI and computer vision (CV), there remains a lack of benchmarks for assessing models' abilities to infer latent…

Computer Vision and Pattern Recognition · Computer Science 2025-10-31 Disheng Liu , Yiran Qiao , Wuche Liu , Yiren Lu , Yunlai Zhou , Tuo Liang , Yu Yin , Jing Ma

Causal Temporal Representation Learning (Ctrl) methods aim to identify the temporal causal dynamics of complex nonstationary temporal sequences. Despite the success of existing Ctrl methods, they require either directly observing the domain…

Machine Learning · Computer Science 2024-09-06 Xiangchen Song , Zijian Li , Guangyi Chen , Yujia Zheng , Yewen Fan , Xinshuai Dong , Kun Zhang

Latent visual reasoning aims to mimic human's imagination process by meditating through hidden states of Multimodal Large Language Models. While recognized as a promising paradigm for visual reasoning, the underlying mechanisms driving its…

Computation and Language · Computer Science 2026-02-27 You Li , Chi Chen , Yanghao Li , Fanhu Zeng , Kaiyu Huang , Jinan Xu , Maosong Sun

Multi-contrast magnetic resonance imaging (MRI) is widely used in clinical practice as each contrast provides complementary information. However, the availability of each imaging contrast may vary amongst patients, which poses challenges to…

Image and Video Processing · Electrical Eng. & Systems 2023-03-31 Jiang Liu , Srivathsa Pasumarthi , Ben Duffy , Enhao Gong , Keshav Datta , Greg Zaharchuk

Deep neural networks have enabled major progresses in semantic segmentation. However, even the most advanced neural architectures suffer from important limitations. First, they are vulnerable to catastrophic forgetting, i.e. they perform…

Computer Vision and Pattern Recognition · Computer Science 2022-02-01 Fabio Cermelli , Massimiliano Mancini , Samuel Rota Buló , Elisa Ricci , Barbara Caputo

Healthcare fraud detection remains a critical challenge due to limited availability of labeled data, constantly evolving fraud tactics, and the high dimensionality of medical records. Traditional supervised methods are challenged by extreme…

Deep learning often faces the challenge of efficiently processing dynamic inputs, such as sensor data or user inputs. For example, an AI writing assistant is required to update its suggestions in real time as a document is edited.…

Machine Learning · Computer Science 2023-07-28 Or Sharir , Anima Anandkumar
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