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The complexity of linear mixed-effects (LME) models means that traditional diagnostics are rendered less effective. This is due to a breakdown of asymptotic results, boundary issues, and visible patterns in residual plots that are…

Methodology · Statistics 2016-12-08 Adam Loy , Heike Hofmann , Dianne Cook

Regression analysis with missing data is a long-standing and challenging problem, particularly when there are many missing variables with arbitrary missing patterns. Likelihood-based methods, although theoretically appealing, are often…

Methodology · Statistics 2024-10-16 Ngok Sang Kwok , Kin Yau Wong

Machine learning models have exhibited exceptional results in various domains. The most prevalent approach for learning is the empirical risk minimizer (ERM), which adapts the model's weights to reduce the loss on a training set and…

Machine Learning · Computer Science 2024-12-11 Koby Bibas

Expectation-Maximization (EM) is a prominent approach for parameter estimation of hidden (aka latent) variable models. Given the full batch of data, EM forms an upper-bound of the negative log-likelihood of the model at each iteration and…

Machine Learning · Computer Science 2020-02-24 Ehsan Amid , Manfred K. Warmuth

In this study, we introduce an innovative methodology aimed at enhancing Fisher's Linear Discriminant Analysis (LDA) in the context of high-dimensional data classification scenarios, specifically addressing situations where each feature…

Applications · Statistics 2024-01-18 Seungyeon Oh , Hoyoung Park

Modelling longitudinal data is an important yet challenging task. These datasets can be high-dimensional, contain non-linear effects and time-varying covariates. Gaussian process (GP) prior-based variational autoencoders (VAEs) have emerged…

Machine Learning · Computer Science 2024-09-18 Priscilla Ong , Manuel Haußmann , Otto Lönnroth , Harri Lähdesmäki

The primary analysis of clinical trials in diabetes therapeutic area often involves a mixed-model repeated measure (MMRM) approach to estimate the average treatment effect for longitudinal continuous outcome, and a generalized linear mixed…

Applications · Statistics 2022-08-03 Lingjing Jiang , Michael Rosenblum , Yu Du

Marginal maximum likelihood (MML) estimation is the preferred approach to fitting item response theory models in psychometrics due to the MML estimator's consistency, normality, and efficiency as the sample size tends to infinity. However,…

Methodology · Statistics 2025-01-08 Christopher J. Urban , Daniel J. Bauer

Linear mixed models (LMMs), which incorporate fixed and random effects, are key tools for analyzing heterogeneous data, such as in personalized medicine. Nowadays, this type of data is increasingly wide, sometimes containing thousands of…

Machine Learning · Statistics 2026-05-15 Ryan Thompson , Matt P. Wand , Joanna J. J. Wang

Linear mixed-effects models have increasingly replaced mixed-model analyses of variance for statistical inference in factorial psycholinguistic experiments. Although LMMs have many advantages over ANOVA, like ANOVAs, setting them up for…

Applications · Statistics 2017-02-14 Hannes Matuschek , Reinhold Kliegl , Shravan Vasishth , Harald Baayen , Douglas Bates

Statistical inference for high dimensional parameters (HDPs) can be based on their intrinsic correlation; that is, parameters that are close spatially or temporally tend to have more similar values. This is why nonlinear mixed-effects…

Methodology · Statistics 2024-01-30 Nan Zheng , Noel Cadigan

To enhance the accuracy of power load forecasting in wind farms, this study introduces an advanced combined forecasting method that integrates Variational Mode Decomposition (VMD) with an Improved Particle Swarm Optimization (IPSO)…

Machine Learning · Computer Science 2024-12-17 Qiang Xie

In this paper, we mainly focus on the penalized maximum likelihood estimation (MLE) of the high-dimensional approximate factor model. Since the current estimation procedure can not guarantee the positive definiteness of the error covariance…

Computation · Statistics 2019-01-18 Shaoxin Wang , Hu Yang , Chaoli Yao

We utilise a sampler originating from nonequilibrium statistical mechanics, termed here Jarzynski-adjusted Langevin algorithm (JALA), to build statistical estimation methods in latent variable models. We achieve this by leveraging…

Computation · Statistics 2025-10-27 James Cuin , Davide Carbone , O. Deniz Akyildiz

This work introduces a new method for selecting the number of components in finite mixture models (FMMs) using variational Bayes, inspired by the large-sample properties of the Evidence Lower Bound (ELBO) derived from mean-field (MF)…

Methodology · Statistics 2026-04-23 Chenyang Wang , Yun Yang

Structural equation models (SEMs) are commonly used to study the structural relationship between observed variables and latent constructs. Recently, Bayesian fitting procedures for SEMs have received more attention thanks to their potential…

Methodology · Statistics 2024-07-12 Khue-Dung Dang , Luca Maestrini , Francis K. C. Hui

Penalized estimation can conduct variable selection and parameter estimation simultaneously. The general framework is to minimize a loss function subject to a penalty designed to generate sparse variable selection. The…

Computation · Statistics 2024-01-11 Zhu Wang

We propose a novel deep clustering method that integrates Variational Autoencoders (VAEs) into the Expectation-Maximization (EM) framework. Our approach models the probability distribution of each cluster with a VAE and alternates between…

Machine Learning · Computer Science 2025-01-14 Michael Adipoetra , Ségolène Martin

A maximum likelihood methodology for the parameters of models with an intractable likelihood is introduced. We produce a likelihood-free version of the stochastic approximation expectation-maximization (SAEM) algorithm to maximize the…

Methodology · Statistics 2018-01-17 Umberto Picchini

Flow Matching (FM) models achieve remarkable results in generative tasks. Building upon diffusion models, FM's simulation-free training paradigm enables simplicity and efficiency but introduces a train-inference gap: model outputs cannot be…

Machine Learning · Computer Science 2026-01-30 Zhaoyi Li , Jingtao Ding , Yong Li , Shihua Li