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Astrocytes, the most abundant type of glial cell, play a fundamental role in memory. Despite most hippocampal synapses being contacted by an astrocyte, there are no current theories that explain how neurons, synapses, and astrocytes might…

Neurons and Cognition · Quantitative Biology 2024-07-24 Leo Kozachkov , Jean-Jacques Slotine , Dmitry Krotov

Classical autoassociative memory models have been central to understanding emergent computations in recurrent neural circuits across diverse biological contexts. However, they typically neglect neuromodulatory agents that are known to…

Neurons and Cognition · Quantitative Biology 2025-12-17 Daiki Goto , Hector Manuel Lopez Rios , Monika Scholz , Suriyanarayanan Vaikuntanathan

The Hopfield recurrent neural network is a classical auto-associative model of memory, in which collections of symmetrically-coupled McCulloch-Pitts neurons interact to perform emergent computation. Although previous researchers have…

Adaptation and Self-Organizing Systems · Physics 2015-06-09 Christopher Hillar , Ngoc M. Tran

The Hopfield associative memory model stores random patterns in synaptic couplings according to Hebb's rule and retrieves them through gradient descent on an energy function. This conventional setting, where neurons are assumed to have…

Disordered Systems and Neural Networks · Physics 2026-01-23 Yoshiyuki Kabashima , Kazushi Mimura

The neuronal paradigm of studying the brain has left us with limitations in both our understanding of how neurons process information to achieve biological intelligence and how such knowledge may be translated into artificial intelligence…

Neurons and Cognition · Quantitative Biology 2020-05-12 Leo Kozachkov , Konstantinos P. Michmizos

Dense associative memory, a fundamental instance of modern Hopfield networks, can store a large number of memory patterns as equilibrium states of recurrent networks. While the stationary-state storage capacity has been investigated, its…

Disordered Systems and Neural Networks · Physics 2025-10-29 Kazushi Mimura , Jun'ichi Takeuchi , Yuto Sumikawa , Yoshiyuki Kabashima , Anthony C. C. Coolen

Associative memory, a form of content-addressable memory, facilitates information storage and retrieval in many biological and physical systems. In statistical mechanics models, associative memory at equilibrium is represented through…

Disordered Systems and Neural Networks · Physics 2022-03-08 Agnish Kumar Behera , Madan Rao , Srikanth Sastry , Suriyanarayanan Vaikuntanathan

High-order extensions of the Hopfield model are known to exhibit dramatically enhanced storage capacity at equilibrium, while their dynamical retrieval properties remain less well understood. In our previous work, we carried out a dynamical…

Statistical Mechanics · Physics 2026-04-06 Yuto Sumikawa , Yoshiyuki Kabashima

The quadratic complexity of self-attention mechanism presents a significant impediment to applying Transformer models to long sequences. This work explores computational principles derived from astrocytes-glial cells critical for biological…

Neural and Evolutionary Computing · Computer Science 2026-03-03 Md Zesun Ahmed Mia , Malyaban Bal , Abhronil Sengupta

We examine a previouly introduced attractor neural network model that explains the persistent activities of neurons in the anterior ventral temporal cortex of the brain. In this model, the coexistence of several attractors including…

Disordered Systems and Neural Networks · Physics 2009-11-10 T. Uezu , A. Hirano , M. Okada

Dense Associative Memories or modern Hopfield networks permit storage and reliable retrieval of an exponentially large (in the dimension of feature space) number of memories. At the same time, their naive implementation is non-biological,…

Neurons and Cognition · Quantitative Biology 2021-04-29 Dmitry Krotov , John Hopfield

Spin-glass models of associative memories are a cornerstone between statistical physics and theoretical neuroscience. In these networks, stochastic spin-like units interact through a synaptic matrix shaped by local Hebbian learning. In…

Disordered Systems and Neural Networks · Physics 2025-04-08 Gianni V. Vinci , Andrea Galluzzi , Maurizio Mattia

Dense Associative Memories or Modern Hopfield Networks have many appealing properties of associative memory. They can do pattern completion, store a large number of memories, and can be described using a recurrent neural network with a…

Neural and Evolutionary Computing · Computer Science 2021-07-29 Dmitry Krotov

A large number of neural network models of associative memory have been proposed in the literature. These include the classical Hopfield networks (HNs), sparse distributed memories (SDMs), and more recently the modern continuous Hopfield…

Neural and Evolutionary Computing · Computer Science 2022-06-20 Beren Millidge , Tommaso Salvatori , Yuhang Song , Thomas Lukasiewicz , Rafal Bogacz

Recent works have highlighted the need for a new dynamical paradigm in the modeling of brain function and evolution. Specifically, these models should incorporate non-constant and asymmetric synaptic weights $T_{ij}$ in the neuron-neuron…

Neurons and Cognition · Quantitative Biology 2025-11-03 Franco Cardin , Alberto Lovison , Amos Maritan , Aram Megighian

The brain can reproduce memories from partial data; this ability is critical for memory recall. The process of memory recall has been studied using auto-associative networks such as the Hopfield model. This kind of model reliably converges…

Neurons and Cognition · Quantitative Biology 2016-05-18 James P. Roach , Leonard M Sander , Michal R. Zochowski

Recent research has established a connection between modern Hopfield networks (HNs) and transformer attention heads, with guarantees of exponential storage capacity. However, these models still face challenges scaling storage efficiently.…

Machine Learning · Computer Science 2025-04-11 Saul Santos , António Farinhas , Daniel C. McNamee , André F. T. Martins

The Hopfield model provides a mathematically idealized yet insightful framework for understanding the mechanisms of memory storage and retrieval in the human brain. This model has inspired four decades of extensive research on learning and…

Neurons and Cognition · Quantitative Biology 2025-05-14 Simone Betteti , Giacomo Baggio , Francesco Bullo , Sandro Zampieri

The Hopfield model describes a neural network that stores memories using all-to-all-coupled spins. Memory patterns are recalled under equilibrium dynamics. Storing too many patterns breaks the associative recall process because frustration…

We propose and analyze a new variation of the so-called {\em exponential Hopfield model}, a recently introduced family of associative neural networks with unprecedented storage capacity. Our construction is based on a cost function defined…

Disordered Systems and Neural Networks · Physics 2025-09-09 Linda Albanese , Andrea Alessandrelli , Adriano Barra , Peter Sollich
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