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We present an agent-driven approach to the construction of parameter inference pipelines for scientific data analysis. Our method leverages a multi-agent system, Cmbagent (the analysis system of the AI scientist Denario), in which…

Artificial Intelligence · Computer Science 2026-04-14 Thomas Borrett , Licong Xu , Andy Nilipour , Boris Bolliet , Sebastien Pierre , Erwan Allys , Celia Lecat , Biwei Dai , Po-Wen Chang , Wahid Bhimji

Multi-Agentic AI systems, powered by large language models (LLMs), are inherently non-deterministic and prone to silent failures such as drift, cycles, and missing details in outputs, which are difficult to detect. We introduce the task of…

Artificial Intelligence · Computer Science 2025-11-07 Divya Pathak , Harshit Kumar , Anuska Roy , Felix George , Mudit Verma , Pratibha Moogi

Recent advances in agentic AI have enabled increasingly autonomous workflows, but existing systems still face substantial challenges in achieving reliable deployment in real-world scientific research. In this work, we present a safe,…

Artificial Intelligence · Computer Science 2026-04-16 Qibin Liu , Julia Gonski

Existing evaluation frameworks for large language models -- including HELM, MT-Bench, AgentBench, and BIG-bench -- are designed for controlled, single-session, lab-scale settings. They do not address the evaluation challenges that emerge…

Artificial Intelligence · Computer Science 2026-05-05 Mukund Pandey

Early identification of cognitive concerns is critical but often hindered by subtle symptom presentation. This study developed and validated a fully automated, multi-agent AI workflow using LLaMA 3 8B to identify cognitive concerns in 3,338…

As data-science agents shift from co-pilots to auto-pilots, silent misframing becomes a critical failure mode. Agents quietly commit to plausible but unintended task framings, producing clean, executable artifacts that hide their incorrect…

Artificial Intelligence · Computer Science 2026-05-12 Josefa Lia Stoisser , Marc Boubnovski Martell , Sidsel Boldsen , Kaspar Märtens , Robert Kitchen

Reproducing computational research is often assumed to be as simple as rerunning the original code with provided data. In practice, missing packages, fragile file paths, version conflicts, or incomplete logic frequently cause analyses to…

Software Engineering · Computer Science 2026-04-24 Syed Mehtab Hussain Shah , Frank Hopfgartner , Arnim Bleier

Artificial intelligence systems for scientific discovery have demonstrated remarkable potential, yet existing approaches remain largely proprietary and operate in batch-processing modes requiring hours per research cycle, precluding…

Artificial Intelligence · Computer Science 2026-01-28 Lukas Weidener , Marko Brkić , Mihailo Jovanović , Ritvik Singh , Chiara Baccin , Emre Ulgac , Alex Dobrin , Aakaash Meduri

AI agents are increasingly deployed to execute important tasks. While rising accuracy scores on standard benchmarks suggest rapid progress, many agents still continue to fail in practice. This discrepancy highlights a fundamental limitation…

Artificial Intelligence · Computer Science 2026-02-24 Stephan Rabanser , Sayash Kapoor , Peter Kirgis , Kangheng Liu , Saiteja Utpala , Arvind Narayanan

Large language models are increasingly being assembled into medical multi-agent systems that emulate multidisciplinary consultation through specialist roles, peer review and consensus formation. In clinical decision support, however,…

Computation and Language · Computer Science 2026-05-28 Yinghao Zhu , Lei Gu , Zixiang Wang , Haoran Sang , Dehao Sui , Wen Tang , Lan Mi , Yasha Wang , Junyi Gao , Liang Yao , Tianfan Fu , Ewen Harrison , Lequan Yu , Liantao Ma

A common problem for agents operating in real-world environments is that the response of an environment to their actions may be non-deterministic and observed through noise. This renders environmental state and progress towards completing a…

Artificial Intelligence · Computer Science 2024-05-21 William E Bishop , Alice Li , Christopher Rawles , Oriana Riva

Large language models can generate scientific simulation code, but the generated code silently fails on most non-textbook problems. We show that classical mathematical validation -- well-posedness, convergence, and error certification --…

Software Engineering · Computer Science 2026-03-30 Chengshuai Yang

AI scientist systems, capable of autonomously executing the full research workflow from hypothesis generation and experimentation to paper writing, hold significant potential for accelerating scientific discovery. However, the internal…

Artificial Intelligence · Computer Science 2025-12-23 Ziming Luo , Atoosa Kasirzadeh , Nihar B. Shah

Scientific workflow systems automate execution -- scheduling, fault tolerance, resource management -- but not the semantic translation that precedes it. Scientists still manually convert research questions into workflow specifications, a…

Artificial Intelligence · Computer Science 2026-04-24 Bartosz Balis , Michal Orzechowski , Piotr Kica , Michal Dygas , Michal Kuszewski

Agentic workflows built on low-code orchestration platforms enable rapid development of multi-agent systems, but they also introduce new and poorly understood failure modes that hinder reliability and maintainability. Unlike traditional…

Artificial Intelligence · Computer Science 2026-03-02 Xuyan Ma , Xiaofei Xie , Yawen Wang , Junjie Wang , Boyu Wu , Mingyang Li , Qing Wang

Autonomous agentic workflows that iteratively refine their own behavior hold considerable promise, yet their failure modes remain poorly characterized. We investigate optimization instability, a phenomenon in which continued autonomous…

Artificial Intelligence · Computer Science 2026-02-19 Cameron Cagan , Pedram Fard , Jiazi Tian , Jingya Cheng , Shawn N. Murphy , Hossein Estiri

Large Language Models (LLMs) are now widely used in astrophysics, but do they actually make our lives easier, or do they merely invent new physics with enough confidence to hide a minus sign? In a specialized field where checking fluent…

Instrumentation and Methods for Astrophysics · Physics 2026-04-01 Chun Huang

Large language model (LLM)-based systems are increasingly deployed to conduct scientific research autonomously, yet whether their reasoning adheres to the epistemic norms that make scientific inquiry self-correcting is poorly understood.…

Organisations are starting to adopt LLM-based AI agents, with their deployments naturally evolving from single agents towards interconnected, multi-agent networks. Yet a collection of safe agents does not guarantee a safe collection of…

Multiagent Systems · Computer Science 2025-08-11 Alistair Reid , Simon O'Callaghan , Liam Carroll , Tiberio Caetano

Information Retrieval is shifting from passive document ranking toward autonomous agentic workflows that operate in multi-step Reason-Act-Observe loops. In such long-horizon trajectories, minor early errors can cascade, leading to…

Artificial Intelligence · Computer Science 2026-04-14 Anushree Sinha , Srivaths Ranganathan , Debanshu Das , Abhishek Dharmaratnakar
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