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Automatic detection of dicentric chromosomes is an essential step to estimate radiation exposure and development of end to end emergency bio dosimetry systems. During accidents, a large amount of data is required to be processed for…

Computer Vision and Pattern Recognition · Computer Science 2022-04-19 Angad Singh Wadhwa , Nikhil Tyagi , Pinaki Roy Chowdhury

Chromosome analysis is vital for diagnosing genetic disorders and guiding cancer therapy decisions through the identification of somatic clonal aberrations. However, developing an AI model are hindered by the overwhelming complexity and…

Quantitative Methods · Quantitative Biology 2025-05-23 Changchun Yang , Weiqian Dai , Yilan Zhang , Siyuan Chen , Jingdong Hu , Junkai Su , Yuxuan Chen , Ao Xu , Na Li , Xin Gao , Yongguo Yu

Chromosome classification is an important but difficult and tedious task in karyotyping. Previous methods only classify manually segmented single chromosome, which is far from clinical practice. In this work, we propose a detection based…

Computer Vision and Pattern Recognition · Computer Science 2021-08-18 Chunlong Luo , Tianqi Yu , Yufan Luo , Manqing Wang , Fuhai Yu , Yinhao Li , Chan Tian , Jie Qiao , Li Xiao

We present a machine learning method capable of accurately detecting chromosome abnormalities that cause blood cancers directly from microscope images of the metaphase stage of cell division. The pipeline is built on a series of fine-tuned…

Chromosome enumeration is an essential but tedious procedure in karyotyping analysis. To automate the enumeration process, we develop a chromosome enumeration framework, DeepACEv2, based on the region based object detection scheme. The…

Computer Vision and Pattern Recognition · Computer Science 2020-07-21 Li Xiao , Chunlong Luo , Tianqi Yu , Yufan Luo , Manqing Wang , Fuhai Yu , Yinhao Li , Chan Tian , Jie Qiao

Chromosome analysis and identification from metaphase images is a critical part of cytogenetics based medical diagnosis. It is mainly used for identifying constitutional, prenatal and acquired abnormalities in the diagnosis of genetic…

Computer Vision and Pattern Recognition · Computer Science 2022-09-13 Amritha S Pallavoor , Prajwal A , Sundareshan TS , Sreekanth K Pallavoor

Objectives: To overcome challenges in diagnosing pericoronitis on panoramic radiographs, an AI-assisted assessment system integrating anatomical localization, pathological classification, and interpretability. Methods: A two-stage deep…

Computer Vision and Pattern Recognition · Computer Science 2026-01-14 Ajo Babu George , Pranav S , Kunal Agarwal

Automated chromosome instance segmentation from metaphase cell microscopic images is critical for the diagnosis of chromosomal disorders (i.e., karyotype analysis). However, it is still a challenging task due to lacking of densely annotated…

Computer Vision and Pattern Recognition · Computer Science 2023-04-26 Dan You , Pengcheng Xia , Qiuzhu Chen , Minghui Wu , Suncheng Xiang , Jun Wang

Cryo-electron tomography (cryo-ET) is an emerging technology for the 3D visualization of structural organizations and interactions of subcellular components at near-native state and sub-molecular resolution. Tomograms captured by cryo-ET…

Quantitative Methods · Quantitative Biology 2020-11-02 Xiangrui Zeng , Min Xu

Biomedical datasets are often constrained by stringent privacy requirements and frequently suffer from severe class imbalance. These two aspects hinder the development of accurate machine learning models. While generative AI offers a…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Jan Carreras Boada , Rao Muhammad Umer , Carsten Marr

Leukemia, a severe form of blood cancer, claims thousands of lives each year. This study focuses on the detection of Acute Lymphoblastic Leukemia (ALL) using advanced image processing and deep learning techniques. By leveraging recent…

Computer Vision and Pattern Recognition · Computer Science 2025-01-14 Alaa Awad , Salah A. Aly

While most previous automation-assisted reading methods can improve efficiency, their performance often relies on the success of accurate cell segmentation and hand-craft feature extraction. This paper presents an efficient and totally…

Computer Vision and Pattern Recognition · Computer Science 2019-12-17 Yao Xiang , Wanxin Sun , Changli Pan , Meng Yan , Zhihua Yin , Yixiong Liang

We present an end-to-end automated workflow that uses large-scale remote compute resources and an embedded GPU platform at the edge to enable AI/ML-accelerated real-time analysis of data collected for x-ray ptychography. Ptychography is a…

Computer Vision and Pattern Recognition · Computer Science 2023-04-11 Anakha V Babu , Tekin Bicer , Saugat Kandel , Tao Zhou , Daniel J. Ching , Steven Henke , Siniša Veseli , Ryan Chard , Antonino Miceli , Mathew Joseph Cherukara

Peripheral blood smears remain a cornerstone in the diagnosis of hematological neoplasms, offering rapid and valuable insights that inform subsequent diagnostic steps. However, since neoplastic transformations typically arise in the bone…

Background: Chromosome karyotype analysis is crucial for diagnosing hereditary diseases, yet detecting structural abnormalities remains challenging. While AI has shown promise in medical imaging, its effectiveness varies across modalities.…

Computer Vision and Pattern Recognition · Computer Science 2025-03-31 Ran Wei , ZhiXiong Lan , Qing Yan , Ning Song , Ming Lv , LongQing Ye

Coherent microscopy techniques provide an unparalleled multi-scale view of materials across scientific and technological fields, from structural materials to quantum devices, from integrated circuits to biological cells. Driven by the…

The expanding applications, utilized by more users, enhance hardware performance and further develop cloud systems for big data processing. This leads to numerous unexplored deep learning applications, especially in advanced computer vision…

Computational Engineering, Finance, and Science · Computer Science 2024-05-07 P. Veysi , M. Adeli , N. Peirov Naziri

Bright-field microscopy, a cost-effective solution for live-cell culture, is often the only resource available, along with standard CPUs, for many low-budget labs. The inherent challenges of bright-field images -- their noisiness, low…

Quantitative Methods · Quantitative Biology 2025-11-03 Surajit Das , Pavel Zun

Cytology is essential for cancer diagnostics and screening due to its minimally invasive nature. However, the development of robust deep learning models for digital cytology is challenging due to the heterogeneity in staining and…

Computer Vision and Pattern Recognition · Computer Science 2025-04-21 Vedrana Ivezić , Ashwath Radhachandran , Ekaterina Redekop , Shreeram Athreya , Dongwoo Lee , Vivek Sant , Corey Arnold , William Speier

Rapid diagnostic tests are crucial for timely disease detection and management, yet accurate interpretation of test results remains challenging. In this study, we propose a novel approach to enhance the accuracy and reliability of rapid…

Computer Vision and Pattern Recognition · Computer Science 2024-11-28 R. B. Dastagir , J. T. Jami , S. Chanda , F. Hafiz , M. Rahman , K. Dey , M. M. Rahman , M. Qureshi , M. M. Chowdhury
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