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Chromosome karyotype analysis is of great clinical importance in the diagnosis and treatment of diseases, especially for genetic diseases. Since manual analysis is highly time and effort consuming, computer-assisted automatic chromosome…

Computer Vision and Pattern Recognition · Computer Science 2021-03-29 Liye Mei , Yalan Yu , Yueyun Weng , Xiaopeng Guo , Yan Liu , Du Wang , Sheng Liu , Fuling Zhou , Cheng Lei

Chromosome classification is critical for karyotyping in abnormality diagnosis. To expedite the diagnosis, we present a novel method named Varifocal-Net for simultaneous classification of chromosome's type and polarity using deep…

Computer Vision and Pattern Recognition · Computer Science 2019-03-21 Yulei Qin , Juan Wen , Hao Zheng , Xiaolin Huang , Jie Yang , Ning Song , Yue-Min Zhu , Lingqian Wu , Guang-Zhong Yang

In the poultry industry, detecting chicken illnesses is essential to avoid financial losses. Conventional techniques depend on manual observation, which is laborious and prone to mistakes. Using YOLO v8 a deep learning model for real-time…

Computer Vision and Pattern Recognition · Computer Science 2025-08-07 Akhil Saketh Reddy Sabbella , Ch. Lakshmi Prachothan , Eswar Kumar Panta

Diagnosis based on medical images, such as X-ray images, often involves manual annotation of anatomical keypoints. However, this process involves significant human efforts and can thus be a bottleneck in the diagnostic process. To fully…

Computer Vision and Pattern Recognition · Computer Science 2024-05-07 Jinhee Kim , Taesung Kim , Taewoo Kim , Jaegul Choo , Dong-Wook Kim , Byungduk Ahn , In-Seok Song , Yoon-Ji Kim

Karyotyping is an important procedure to assess the possible existence of chromosomal abnormalities. However, because of the non-rigid nature, chromosomes are usually heavily curved in microscopic images and such deformed shapes hinder the…

Computer Vision and Pattern Recognition · Computer Science 2022-07-04 Sunyi Zheng , Jingxiong Li , Zhongyi Shui , Chenglu Zhu , Yunlong Zhang , Pingyi Chen , Lin Yang

Thousands of individuals succumb annually to leukemia alone. As artificial intelligence-driven technologies continue to evolve and advance, the question of their applicability and reliability remains unresolved. This study aims to utilize…

Image and Video Processing · Electrical Eng. & Systems 2025-02-17 Alaa Awad , Salah A. Aly

Quality control of medical images is a critical component of digital pathology, ensuring that diagnostic images meet required standards. A pre-analytical task within this process is the verification of the number of specimen fragments, a…

Efficient detection and classification of blood cells are vital for accurate diagnosis and effective treatment of blood disorders. This study utilizes a YOLOv10 model trained on Roboflow data with images resized to 640x640 pixels across…

Image and Video Processing · Electrical Eng. & Systems 2025-08-19 Shilpa Choudhary , Sandeep Kumar , Pammi Sri Siddhaarth , Guntu Charitasri

The brightfield microscope is instrumental in the visual examination of both biological and physical samples at sub-millimeter scales. One key clinical application has been in cancer histopathology, where the microscopic assessment of the…

Computer Vision and Pattern Recognition · Computer Science 2020-06-03 Po-Hsuan Cameron Chen , Krishna Gadepalli , Robert MacDonald , Yun Liu , Kunal Nagpal , Timo Kohlberger , Jeffrey Dean , Greg S. Corrado , Jason D. Hipp , Martin C. Stumpe

The widespread use of charts and infographics as a means of data visualization in various domains has inspired recent research in automated chart understanding. However, information extraction from chart images is a complex multitasked…

Computer Vision and Pattern Recognition · Computer Science 2024-08-30 Osama Mustafa , Muhammad Khizer Ali , Momina Moetesum , Imran Siddiqi

We present KAYRA, an end-to-end karyotyping system that operates inside the operational constraints of a clinical cytogenetic laboratory. KAYRA is architected as a containerized microservice pipeline whose ML stack combines an…

Chromosome recognition is an essential task in karyotyping, which plays a vital role in birth defect diagnosis and biomedical research. However, existing classification methods face significant challenges due to the inter-class similarity…

Computer Vision and Pattern Recognition · Computer Science 2023-12-14 Ruijia Chang , Suncheng Xiang , Chengyu Zhou , Kui Su , Dahong Qian , Jun Wang

Histopathological image analysis is the gold standard to diagnose cancer. Carcinoma is a subtype of cancer that constitutes more than 80% of all cancer cases. Squamous cell carcinoma and adenocarcinoma are two major subtypes of carcinoma,…

Image and Video Processing · Electrical Eng. & Systems 2022-01-20 Swathi Prabhua , Keerthana Prasada , Antonio Robels-Kelly , Xuequan Lu

Deep learning has demonstrated expert-level performance in melanoma classification, positioning it as a powerful tool in clinical dermatology. However, model opacity and the lack of interpretability remain critical barriers to clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Junwen Zheng , Xinran Xu , Li Rong Wang , Chang Cai , Lucinda Siyun Tan , Dingyuan Wang , Hong Liang Tey , Xiuyi Fan

Manual operation of microscopes for repetitive tasks in cell biology is a significant bottleneck, consuming invaluable expert time, and introducing human error. Automation is essential, and while Digital Holographic Microscopy (DHM) offers…

Complete blood cell detection holds significant value in clinical diagnostics. Conventional manual microscopy methods suffer from time inefficiency and diagnostic inaccuracies. Existing automated detection approaches remain constrained by…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Guohua Wu , Shengqi Chen , Pengchao Deng , Wenting Yu

Stem cell-derived organoids are a promising tool to model native human tissues as they resemble human organs functionally and structurally compared to traditional monolayer cell-based assays. For instance, colon organoids can spontaneously…

Quantitative Methods · Quantitative Biology 2022-10-14 Lyan Abdul , Jocelyn Xu , Alexander Sotra , Abbas Chaudary , Jerry Gao , Shravanthi Rajasekar , Nicky Anvari , Hamidreza Mahyar , Boyang Zhang

Identifying metabolic sites where cytochrome P450 enzymes metabolize small-molecule drugs is essential for drug discovery. Although existing computational approaches have been proposed for site-of-metabolism prediction, they typically…

Quantitative Methods · Quantitative Biology 2026-01-30 Hajung Kim , Eunha Lee , Sohyun Chung , Jueon Park , Seungheun Baek , Jaewoo Kang

Recently, the integration of advanced simulation technologies with artificial intelligence (AI) is revolutionizing science and engineering research. ChronoLlama introduces a novel framework that customizes the open-source LLMs, specifically…

Software Engineering · Computer Science 2025-01-09 Jingquan Wang , Harry Zhang , Khailanii Slaton , Shu Wang , Radu Serban , Jinlong Wu , Dan Negrut

We present an enhanced YOLOv8 real time vehicle detection and classification framework, for estimating carbon emissions in urban environments. The system enhances YOLOv8 architecture to detect, segment, and track vehicles from live traffic…

Computer Vision and Pattern Recognition · Computer Science 2025-06-25 Ammar K Al Mhdawi , Nonso Nnamoko , Safanah Mudheher Raafat , M. K. S. Al-Mhdawi , Amjad J Humaidi