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The recent advancement of pre-trained Transformer models has propelled the development of effective text mining models across various biomedical tasks. However, these models are primarily learned on the textual data and often lack the…

Computation and Language · Computer Science 2021-07-02 Sriram Pingali , Shweta Yadav , Pratik Dutta , Sriparna Saha

In this paper, we introduce MIO, a novel foundation model built on multimodal tokens, capable of understanding and generating speech, text, images, and videos in an end-to-end, autoregressive manner. While the emergence of large language…

Most biological processes are described as a series of interactions between proteins and other molecules, and interactions are in turn described in terms of atomic structures. To annotate protein functions as sets of interaction states at…

Biomolecules · Quantitative Biology 2012-02-13 Akira R. Kinjo , Haruki Nakamura

Multimodal clinical records contain structured measurements and clinical notes recorded over time, offering rich temporal information about the evolution of patient health. Yet these observations are sparse, and whether they are recorded…

Machine Learning · Computer Science 2026-04-24 Zihan Liang , Ziwen Pan , Ruoxuan Xiong

Vision Language Models (VLMs) encode multimodal inputs over large, complex, and difficult-to-interpret architectures, which limit transparency and trust. We propose a Multimodal Inversion for Model Interpretation and Conceptualization…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Animesh Jain , Alexandros Stergiou

We propose a two-stage multimodal framework that enhances disease classification and region-aware radiology report generation from chest X-rays, leveraging the MIMIC-Eye dataset. In the first stage, we introduce a gaze-guided contrastive…

Computer Vision and Pattern Recognition · Computer Science 2025-08-19 Tanjim Islam Riju , Shuchismita Anwar , Saman Sarker Joy , Farig Sadeque , Swakkhar Shatabda

Accurate biodiversity identification from large-scale field data is a foundational problem with direct impact on ecology, conservation, and environmental monitoring. In practice, the core task is taxonomic prediction - inferring order,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Sk Miraj Ahmed , Xi Yu , Yunqi Li , Yuewei Lin , Wei Xu

Large Multimodal Models (LMMs) exhibit remarkable multi-tasking ability by learning mixed instruction datasets. However, novel tasks would be encountered sequentially in dynamic world, which urges for equipping LMMs with multimodal…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Fanhu Zeng , Fei Zhu , Haiyang Guo , Xu-Yao Zhang , Cheng-Lin Liu

In-context learning (ICL) enables task adaptation at inference time by conditioning on demonstrations rather than updating model parameters. Although recent time-series foundation models incorporate contextual conditioning, retrieval, or…

Machine Learning · Computer Science 2026-05-15 Anish Saha , Konstantin Shmakov

We investigated visual reasoning limitations of both multimodal large language models (MLLMs) and image generation models (IGMs) by creating a novel benchmark to systematically compare failure modes across image-to-text and text-to-image…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Aahana Basappa , Pranay Goel , Anusri Karra , Anish Karra , Asa Gilmore , Kevin Zhu

The primary output of the nervous system is movement and behavior. While recent advances have democratized pose tracking during complex behavior, kinematic trajectories alone provide only indirect access to the underlying control processes.…

Multimodal learning typically relies on the assumption that all modalities are fully available during both the training and inference phases. However, in real-world scenarios, consistently acquiring complete multimodal data presents…

Computer Vision and Pattern Recognition · Computer Science 2024-07-18 Donggeun Kim , Taesup Kim

Recent advances in vision-language pre-training have enabled machines to perform better in multimodal object discrimination (e.g., image-text semantic alignment) and image synthesis (e.g., text-to-image generation). On the other hand,…

Computer Vision and Pattern Recognition · Computer Science 2023-06-02 Xiao Dong , Runhui Huang , Xiaoyong Wei , Zequn Jie , Jianxing Yu , Jian Yin , Xiaodan Liang

Foundation models (FMs) have exhibited remarkable performance across a wide range of downstream tasks in many domains. Nevertheless, general-purpose FMs often face challenges when confronted with domain-specific problems, due to their…

Computational Engineering, Finance, and Science · Computer Science 2023-08-22 Yizhen Luo , Jiahuan Zhang , Siqi Fan , Kai Yang , Yushuai Wu , Mu Qiao , Zaiqing Nie

Despite the wealth of single-cell multi-omics data, it remains challenging to predict the consequences of novel genetic and chemical perturbations in the human body. It requires knowledge of molecular interactions at all biological levels,…

Artificial Intelligence · Computer Science 2025-01-22 You Wu , Lei Xie

Generative models in molecular design tend to be richly parameterized, data-hungry neural models, as they must create complex structured objects as outputs. Estimating such models from data may be challenging due to the lack of sufficient…

Machine Learning · Computer Science 2021-08-17 Kevin Yang , Wengong Jin , Kyle Swanson , Regina Barzilay , Tommi Jaakkola

We present MiMo-7B, a large language model born for reasoning tasks, with optimization across both pre-training and post-training stages. During pre-training, we enhance the data preprocessing pipeline and employ a three-stage data mixing…

Molecular dynamics (MD) simulations are essential tools in computational chemistry and drug discovery, offering crucial insights into dynamic molecular behavior. However, their utility is significantly limited by substantial computational…

Chemical Physics · Physics 2025-09-04 Bin Feng , Jiying Zhang , Xinni Zhang , Zijing Liu , Yu Li

Language models have emerged as powerful predictors of the viability of biological sequences. During training these models learn the rules of the grammar obeyed by sequences of amino acids or nucleotides. Once trained, these models can take…

Machine Learning · Computer Science 2025-04-25 Pranav Kantroo , Günter P. Wagner , Benjamin B. Machta

Learning effective joint embedding for cross-modal data has always been a focus in the field of multimodal machine learning. We argue that during multimodal fusion, the generated multimodal embedding may be redundant, and the discriminative…

Machine Learning · Computer Science 2022-12-06 Sijie Mai , Ying Zeng , Haifeng Hu